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This article considers the problem of analyzing associations between power spectra of multiple time series and cross-sectional outcomes when data are observed from multiple subjects. The motivating application comes from sleep medicine,…

Applications · Statistics 2017-01-19 Robert T. Krafty , Ori Rosen , David S. Stoffer , Daniel J. Buysse , Martica H. Hall

Network structures underlie the dynamics of many complex phenomena, from gene regulation and foodwebs to power grids and social media. Yet, as they often cannot be observed directly, their connectivities must be inferred from observations…

Machine Learning · Computer Science 2023-11-02 Thomas Gaskin , Grigorios A. Pavliotis , Mark Girolami

This paper addresses learning of sparse structural changes or differential network between two classes of non-paranormal graphical models. We assume a multi-source and heterogeneous dataset is available for each class, where the covariance…

Machine Learning · Computer Science 2024-10-04 Mojtaba Nikahd , Seyed Abolfazl Motahari

Statistical inference of genetic regulatory networks is essential for understanding temporal interactions of regulatory elements inside the cells. For inferences of large networks, identification of network structure is typical achieved…

Quantitative Methods · Quantitative Biology 2008-04-07 Heng Lian

High-dimensional multivariate time series are common in many scientific and industrial applications, where the interest lies in identifying key dependence structure within the data for subsequent analysis tasks, such as forecasting. An…

Methodology · Statistics 2025-12-15 Madeline A. Shelley , Chiara Boetti , Marina I. Knight , Matthew A. Nunes

Epilepsy affects around 50 million people globally. Electroencephalography (EEG) or Magnetoencephalography (MEG) based spike detection plays a crucial role in diagnosis and treatment. Manual spike identification is time-consuming and…

Machine Learning · Statistics 2026-03-16 Fangyi Wei , Jiajie Mo , Kai Zhang , Haipeng Shen , Srikantan Nagarajan , Fei Jiang

We introduce a novel, data-driven topological data analysis (TDA) approach for embedding brain networks into a lower-dimensional space in quantifying the dynamics of temporal lobe epilepsy (TLE) obtained from resting-state functional…

While the volume of electronic health records (EHR) data continues to grow, it remains rare for hospital systems to capture dense physiological data streams, even in the data-rich intensive care unit setting. Instead, typical EHR records…

Machine Learning · Computer Science 2018-12-04 Satya Narayan Shukla , Benjamin M. Marlin

We consider linear models for stochastic dynamics. To any such model can be associated a network (namely a directed graph) describing which degrees of freedom interact under the dynamics. We tackle the problem of learning such a network…

Statistics Theory · Mathematics 2011-03-01 José Bento , Morteza Ibrahimi , Andrea Montanari

Epilepsy which is characterized by seizures is studied using EEG signals by recording the electrical activity of the brain. Different types of communication between different parts of the brain are characterized by many state of the art…

Machine Learning · Computer Science 2020-09-29 Mohammad Mansour , Fouad Khnaisser , Hmayag Partamian

The brain's structural and functional systems, protein-protein interaction, and gene networks are examples of biological systems that share some features of complex networks, such as highly connected nodes, modularity, and small-world…

This paper revisits the classical concept of network modularity and its spectral relaxations used throughout graph data analysis. We formulate and study several modularity statistic variants for which we establish asymptotic distributional…

Methodology · Statistics 2024-02-26 Anirban Mitra , Konasale Prasad , Joshua Cape

In an era of unprecedented deluge of (mostly unstructured) data, graphs are proving more and more useful, across the sciences, as a flexible abstraction to capture complex relationships between complex objects. One of the main challenges…

Disordered Systems and Neural Networks · Physics 2016-10-17 Alaa Saade

Electroencephalography (EEG) monitors ---by either intrusive or noninvasive electrodes--- time and frequency variations and spectral content of voltage fluctuations or waves, known as brain rhythms, which in some way uncover activity during…

Neurons and Cognition · Quantitative Biology 2019-03-13 Javier A. Galadí , Joaquín J. Torres , J. Marro

Anomaly subsequence detection is to detect inconsistent data, which always contains important information, among time series. Due to the high dimensionality of the time series, traditional anomaly detection often requires a large time…

Machine Learning · Computer Science 2019-07-02 Chunkai Zhang , Yingyang Chen , Ao Yin

Clinical medical data, especially in the intensive care unit (ICU), consist of multivariate time series of observations. For each patient visit (or episode), sensor data and lab test results are recorded in the patient's Electronic Health…

Machine Learning · Computer Science 2017-03-23 Zachary C. Lipton , David C. Kale , Charles Elkan , Randall Wetzel

To understand how neural networks process information, it is important to investigate how neural network dynamics varies with respect to different stimuli. One challenging task is to design efficient statistical approaches to analyze…

Neurons and Cognition · Quantitative Biology 2018-11-30 Zhi-Qin John Xu , Douglas Zhou , David Cai

Predator-prey networks originating from different aqueous and terrestrial environments are compared to assess if the difference in environments of these networks produce any significant difference in the structure of such predator-prey…

Populations and Evolution · Quantitative Biology 2019-01-11 Shashankaditya Upadhyay , Sudeepto Bhattacharya

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

Neurons and Cognition · Quantitative Biology 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Two-dimensional electronic spectroscopy has become one of the main experimental tools for analyzing the dynamics of excitonic energy transfer in large molecular complexes. Simplified theoretical models are usually employed to extract model…

Chemical Physics · Physics 2019-01-17 Mirta Rodríguez , Tobias Kramer