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Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

Differentiating between the two main subtypes of Inflammatory Bowel Disease (IBD): Crohns disease (CD) and ulcerative colitis (UC) is a persistent clinical challenge due to overlapping presentations. This study introduces a novel…

Genomics · Quantitative Biology 2026-01-14 Myles Joshua Toledo Tan , Maria Kapetanaki , Panayiotis V. Benos

Building accurate and robust artificial intelligence systems for medical image assessment requires not only the research and design of advanced deep learning models but also the creation of large and curated sets of annotated training…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Florin C. Ghesu , Bogdan Georgescu , Awais Mansoor , Youngjin Yoo , Dominik Neumann , Pragneshkumar Patel , R. S. Vishwanath , James M. Balter , Yue Cao , Sasa Grbic , Dorin Comaniciu

Bladder cancer ranks within the top 10 most diagnosed cancers worldwide and is among the most expensive cancers to treat due to the high recurrence rates which require lifetime follow-ups. The primary tool for diagnosis is cystoscopy, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-07 Meryem Amaouche , Ouassim Karrakchou , Mounir Ghogho , Anouar El Ghazzaly , Mohamed Alami , Ahmed Ameur

Early detection of cancer is crucial for treatment and overall patient survival. In the upper aerodigestive tract (UADT) the gold standard for identification of malignant tissue is an invasive biopsy. Recently, non-invasive imaging…

Computer Vision and Pattern Recognition · Computer Science 2019-10-10 Nils Gessert , Matthias Schlüter , Sarah Latus , Veronika Volgger , Christian Betz , Alexander Schlaefer

Histological evaluation of tissue samples is a typical approach to identify colorectal cancer metastases in the peritoneum. For immediate assessment, reliable and real-time in-vivo imaging would be required. For example, intraoperative…

Computer Vision and Pattern Recognition · Computer Science 2019-03-07 Nils Gessert , Lukas Wittig , Daniel Drömann , Tobias Keck , Alexander Schlaefer , David B. Ellebrecht

The analysis of carotid arteries, particularly plaques, in multi-sequence Magnetic Resonance Imaging (MRI) data is crucial for assessing the risk of atherosclerosis and ischemic stroke. In order to evaluate metrics and radiomic features,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Marie-Christine Pali , Christina Schwaiger , Malik Galijasevic , Valentin K. Ladenhauf , Stephanie Mangesius , Elke R. Gizewski

Colorectal cancer is the fourth leading cause of cancer deaths worldwide and the second leading cause in the United States. The risk of colorectal cancer can be mitigated by the identification and removal of premalignant lesions through…

Computer Vision and Pattern Recognition · Computer Science 2017-11-29 Faisal Mahmood , Nicholas J. Durr

Colorectal cancer (CRC) ranks as the second leading cause of cancer-related deaths and the third most prevalent malignant tumour worldwide. Early detection of CRC remains problematic due to its non-specific and often embarrassing symptoms,…

Machine Learning · Computer Science 2025-04-25 Natalia Sikora , Robert L. Manschke , Alethea M. Tang , Peter Dunstan , Dean A. Harris , Su Yang

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Chronic wounds including diabetic and arterial/venous insufficiency injuries have become a major burden for healthcare systems worldwide. Demographic changes suggest that wound care will play an even bigger role in the coming decades.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Maja Schlereth , Daniel Stromer , Yash Mantri , Jason Tsujimoto , Katharina Breininger , Andreas Maier , Caesar Anderson , Pranav S. Garimella , Jesse V. Jokerst

We explore the potential of CNN-based models for gallbladder cancer (GBC) detection from ultrasound (USG) images as no prior study is known. USG is the most common diagnostic modality for GB diseases due to its low cost and accessibility.…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Soumen Basu , Mayank Gupta , Pratyaksha Rana , Pankaj Gupta , Chetan Arora

The automatic and objective medical diagnostic model can be valuable to achieve early cancer detection, and thus reducing the mortality rate. In this paper, we propose a highly efficient multi-level malignant tissue detection through the…

Image and Video Processing · Electrical Eng. & Systems 2020-07-01 Chuang Zhu , Ke Mei , Ting Peng , Yihao Luo , Jun Liu , Ying Wang , Mulan Jin

Acute and chronic wounds are a challenge to healthcare systems around the world and affect many people's lives annually. Wound classification is a key step in wound diagnosis that would help clinicians to identify an optimal treatment…

Computer Vision and Pattern Recognition · Computer Science 2021-06-07 Behrouz Rostami , D. M. Anisuzzaman , Chuanbo Wang , Sandeep Gopalakrishnan , Jeffrey Niezgoda , Zeyun Yu

Pressure ulcers are a challenge for patients and healthcare professionals. In the UK, 700,000 people are affected by pressure ulcers each year. Treating them costs the National Health Service {\pounds}3.8 million every day. Their etiology…

Machine Learning · Computer Science 2022-03-15 Paul Fergus , Carl Chalmers , William Henderson , Danny Roberts , Atif Waraich

Colonoscopy screening effectively identifies and removes polyps before they progress to colorectal cancer (CRC), but current follow-up guidelines rely primarily on histopathological features, overlooking other important CRC risk factors.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Shuai Jiang , Christina Robinson , Joseph Anderson , William Hisey , Lynn Butterly , Arief Suriawinata , Saeed Hassanpour

Plant diseases serve as one of main threats to food security and crop production. It is thus valuable to exploit recent advances of artificial intelligence to assist plant disease diagnosis. One popular approach is to transform this problem…

Computer Vision and Pattern Recognition · Computer Science 2020-03-19 Ruifeng Shi , Deming Zhai , Xianming Liu , Junjun Jiang , Wen Gao

Deriving interpretable prognostic features from deep-learning-based prognostic histopathology models remains a challenge. In this study, we developed a deep learning system (DLS) for predicting disease specific survival for stage II and III…

Carotid artery stenosis is the narrowing of carotid arteries, which supplies blood to the neck and head. In this work, we train a model to predict the severity of the stenosis blockage based on SRUC criteria variables and other patient…

Quantitative Methods · Quantitative Biology 2021-08-03 Yiqun Diao , Oliver Zhao , Priya Kothapalli , Peter Monteleone , Chandrajit Bajaj

Self-supervised learning (SSL) has led to important breakthroughs in computer vision by allowing learning from large amounts of unlabeled data. As such, it might have a pivotal role to play in biomedicine where annotating data requires a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Roy Hirsch , Mathilde Caron , Regev Cohen , Amir Livne , Ron Shapiro , Tomer Golany , Roman Goldenberg , Daniel Freedman , Ehud Rivlin