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With the widespread deployment of dashcams and advancements in computer vision, developing accident prediction models from the dashcam perspective has become critical for proactive safety interventions. However, two key challenges persist:…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Tongshuai Wu , Chao Lu , Ze Song , Yunlong Lin , Sizhe Fan , Xuemei Chen

Deep learning recommendation systems rely on feature interaction modules to model complex user-item relationships across sparse categorical and dense features. In large-scale ad ranking, increasing model capacity is a promising path to…

Machine Learning · Computer Science 2026-02-11 Jiacheng Li , Yixiong Meng , Yi wu , Yun Zhao , Sharare Zehtabian , Jiayin Jin , Degao Peng , Jinfeng Zhuang , Qifei Shen , Kungang Li

Drug-drug interactions (DDIs) are a major concern in clinical practice, as they can lead to reduced therapeutic efficacy or severe adverse effects. Traditional computational approaches often struggle to capture the complex relationships…

Machine Learning · Computer Science 2025-08-27 Hongbo Liu , Siyi Li , Zheng Yu

Accurate prediction of Drug-Target Affinity (DTA) is crucial for reducing experimental costs and accelerating early screening in computational drug discovery. While sequence-based deep learning methods avoid reliance on costly 3D…

Machine Learning · Computer Science 2025-11-03 Minghui Li , Yuanhang Wang , Peijin Guo , Wei Wan , Shengshan Hu , Shengqing Hu

Traditional biomedical version of embeddings obtained from pre-trained language models have recently shown state-of-the-art results for relation extraction (RE) tasks in the medical domain. In this paper, we explore how to incorporate…

Computation and Language · Computer Science 2020-12-23 Ishani Mondal

Drug recommendation is an essential task in machine learning-based clinical decision support systems. However, the risk of drug-drug interactions (DDI) between co-prescribed medications remains a significant challenge. Previous studies have…

Machine Learning · Computer Science 2025-10-10 Chongmyung Kwon , Yujin Kim , Seoeun Park , Yunji Lee , Charmgil Hong

Click-through rate (CTR) prediction plays an important role in online advertising and recommender systems. In practice, the training of CTR models depends on click data which is intrinsically biased towards higher positions since higher…

Information Retrieval · Computer Science 2021-06-18 Jianqiang Huang , Ke Hu , Qingtao Tang , Mingjian Chen , Yi Qi , Jia Cheng , Jun Lei

Identifying protein-protein interactions (PPI) is crucial for gaining in-depth insights into numerous biological processes within cells and holds significant guiding value in areas such as drug development and disease treatment. Currently,…

Quantitative Methods · Quantitative Biology 2025-01-30 Jiang Li , Yuan-Ting Li

Predicting the interaction between a compound and a target is crucial for rapid drug repurposing. Deep learning has been successfully applied in drug-target affinity (DTA) problem. However, previous deep learning-based methods ignore…

Machine Learning · Computer Science 2020-09-29 Tri Minh Nguyen , Thin Nguyen , Thao Minh Le , Truyen Tran

Protein-protein interaction (PPI) represents a central challenge within the biology field, and accurately predicting the consequences of mutations in this context is crucial for drug design and protein engineering. Deep learning (DL) has…

Machine Learning · Computer Science 2026-01-13 Fang Wu , Stan Z. Li

The extraction of interactions between chemicals and proteins from several biomedical articles is important in many fields of biomedical research such as drug development and prediction of drug side effects. Several natural language…

Computation and Language · Computer Science 2020-11-05 Dongha Choi , Hyunju Lee

Click-through rate prediction is an essential task in industrial applications, such as online advertising. Recently deep learning based models have been proposed, which follow a similar Embedding\&MLP paradigm. In these methods large scale…

Machine Learning · Statistics 2018-09-14 Guorui Zhou , Chengru Song , Xiaoqiang Zhu , Ying Fan , Han Zhu , Xiao Ma , Yanghui Yan , Junqi Jin , Han Li , Kun Gai

CTR (Click-Through Rate) prediction, crucial for recommender systems and online advertising, etc., has been confirmed to benefit from modeling long-term user behaviors. Nonetheless, the vast number of behaviors and complexity of noise…

Information Retrieval · Computer Science 2025-09-22 Weijiang Lai , Beihong Jin , Yapeng Zhang , Yiyuan Zheng , Rui Zhao , Jian Dong , Jun Lei , Xingxing Wang

Polypharmacy, defined as the use of multiple drugs together, is a standard treatment method, especially for severe and chronic diseases. However, using multiple drugs together may cause interactions between drugs. Drug-drug interaction…

Machine Learning · Computer Science 2022-07-13 Farhan Tanvir , Khaled Mohammed Saifuddin , Esra Akbas

Accurately predicting drug-drug interactions (DDI) for emerging drugs, which offer possibilities for treating and alleviating diseases, with computational methods can improve patient care and contribute to efficient drug development.…

Quantitative Methods · Quantitative Biology 2023-11-17 Yongqi Zhang , Quanming Yao , Ling Yue , Xian Wu , Ziheng Zhang , Zhenxi Lin , Yefeng Zheng

In the surveillance and defense domain, multi-target detection and classification (MTD) is considered essential yet challenging due to heterogeneous inputs from diverse data sources and the computational complexity of algorithms designed…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Ngoc Tuyen Do , Tri Nhu Do

Interference between pharmacological substances can cause serious medical injuries. Correctly predicting so-called drug-drug interactions (DDI) does not only reduce these cases but can also result in a reduction of drug development cost.…

Machine Learning · Computer Science 2019-08-06 Md. Rezaul Karim , Michael Cochez , Joao Bosco Jares , Mamtaz Uddin , Oya Beyan , Stefan Decker

Protein-protein interactions (PPIs) are crucial in regulating numerous cellular functions, including signal transduction, transportation, and immune defense. As the accuracy of multi-chain protein complex structure prediction improves, the…

Biomolecules · Quantitative Biology 2024-02-07 Chenqing Hua , Connor Coley , Guy Wolf , Doina Precup , Shuangjia Zheng

We are assisting at a growing interest in the development of learning architectures with application to digital communication systems. Herein, we consider the detection/decoding problem. We aim at developing an optimal neural architecture…

Information Theory · Computer Science 2022-09-02 Andrea M. Tonello , Nunzio A. Letizia

In the treatment of complex diseases, treatment regimens using a single drug often yield limited efficacy and can lead to drug resistance. In contrast, combination drug therapies can significantly improve therapeutic outcomes through…

Machine Learning · Computer Science 2026-04-24 Jiyan Song , Wenyang Wang , Chengcheng Yan , Zhiquan Han , Feifei Zhao