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Dynamic predictive modelling using electronic health record (EHR) data has gained significant attention in recent years. The reliability and trustworthiness of such models depend heavily on the quality of the underlying data, which is, in…

The surging availability of electronic medical records (EHR) leads to increased research interests in medical predictive modeling. Recently many deep learning based predicted models are also developed for EHR data and demonstrated…

Machine Learning · Computer Science 2018-02-15 Mengying Sun , Fengyi Tang , Jinfeng Yi , Fei Wang , Jiayu Zhou

We studied how lagged linear regression can be used to detect the physiologic effects of drugs from data in the electronic health record (EHR). We systematically examined the effect of methodological variations ((i) time series…

Methodology · Statistics 2018-01-29 Matthew E. Levine , David J. Albers , George Hripcsak

Introduction: One of the most important tasks in the Emergency Department (ED) is to promptly identify the patients who will benefit from hospital admission. Machine Learning (ML) techniques show promise as diagnostic aids in healthcare.…

Although improving financial access is in the spotlight of the current U.S. health policy agenda, this alone does not address universal and comprehensive healthcare. Affordability is one barrier to healthcare, but others such as…

Applications · Statistics 2015-01-16 Mallory Nobles , Nicoleta Serban , Julie Swann

Current cancer screening guidelines cover only a few cancer types and rely on narrowly defined criteria such as age or a single risk factor like smoking history, to identify high-risk individuals. Predictive models using electronic health…

Machine Learning · Computer Science 2026-01-27 Jiheum Park , Chao Pang , Tristan Y. Lee , Jeong Yun Yang , Jacob Berkowitz , Alexander Z. Wei , Nicholas Tatonetti

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Measurement error arises commonly in clinical research settings that rely on data from electronic health records or large observational cohorts. In particular, self-reported outcomes are typical in cohort studies for chronic diseases such…

Methodology · Statistics 2021-02-08 Lillian A. Boe , Lesley F. Tinker , Pamela A. Shaw

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Electronic Health Records (EHR) are generated from clinical routine care recording valuable information of broad patient populations, which provide plentiful opportunities for improving patient management and intervention strategies in…

Machine Learning · Computer Science 2023-04-13 Changshuo Liu , Wenqiao Zhang , Beng Chin Ooi , James Wei Luen Yip , Lingze Zeng , Kaiping Zheng

What is the impact of private equity (PE) investment on healthcare value? Does PE investment hurt or improve healthcare value, and if so, can its effect be mitigated through the use of health information technologies (IT)? Given the…

General Economics · Economics 2025-12-25 Minghong Yuan , Wen Wen , Indranil Bardhan

Elderly ICU patients with coexisting diabetes mellitus and heart failure experience markedly elevated short-term mortality, yet few predictive models are tailored to this high-risk group. Diabetes mellitus affects nearly 30% of U.S. adults…

Applications · Statistics 2025-06-19 Junyi Fan , Shuheng Chen , Li Sun , Yong Si , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Drug shortages occur frequently and are often caused by supply chain disruptions. For improvements to occur, it is necessary to be able to estimate the vulnerability of pharmaceutical supply chains. In this work, we present the first model…

Optimization and Control · Mathematics 2022-04-26 Emily L. Tucker , Mark S. Daskin

Multiple Sclerosis (MS) is a chronic disease developed in human brain and spinal cord, which can cause permanent damage or deterioration of the nerves. The severity of MS disease is monitored by the Expanded Disability Status Scale (EDSS),…

Machine Learning · Computer Science 2023-04-11 Kai Zhang , John A. Lincoln , Xiaoqian Jiang , Elmer V. Bernstam , Shayan Shams

Predicting health risks from electronic health records (EHR) is a topic of recent interest. Deep learning models have achieved success by modeling temporal and feature interaction. However, these methods learn insufficient representations…

Machine Learning · Computer Science 2023-12-19 Zhihao Yu , Chaohe Zhang , Yasha Wang , Wen Tang , Jiangtao Wang , Liantao Ma

Healthcare quality metrics refer to a variety of measures used to characterize what should have been done or not done for a patient or the health consequences of what was or was not done. When estimating healthcare quality, many metrics are…

Applications · Statistics 2025-02-13 Sharon-Lise Normand , Katya Zelevinsky , Marcela Horvitz-Lennon

This study investigates how machine learning (ML) models can predict hospital readmissions for diabetic patients fairly and accurately across different demographics (age, gender, race). We compared models like Deep Learning, Generalized…

Machine Learning · Computer Science 2024-03-29 Zainab Al-Zanbouri , Gauri Sharma , Shaina Raza

Due to escalating healthcare costs, accurately predicting which patients will incur high costs is an important task for payers and providers of healthcare. High-cost claimants (HiCCs) are patients who have annual costs above $\$250,000$ and…

In high-stakes settings where machine learning models are used to automate decision-making about individuals, the presence of algorithmic bias can exacerbate systemic harm to certain subgroups of people. These biases often stem from the…

Machine Learning · Computer Science 2026-04-07 Erin Tan , Judy Hanwen Shen , Irene Y. Chen

Biases in automated clinical decision-making using Electronic Healthcare Records (EHR) impose significant disparities in patient care and treatment outcomes. Conventional approaches have primarily focused on bias mitigation strategies…

Artificial Intelligence · Computer Science 2024-12-03 Resmi Ramachandranpillai , Kishore Sampath , Ayaazuddin Mohammad , Malihe Alikhani
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