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Plasticity-led evolution is a form of evolution where a change in the environment induces novel traits via phenotypic plasticity, after which the novel traits are genetically accommodated over generations under the novel environment. This…

Populations and Evolution · Quantitative Biology 2023-01-18 Eden Tian Hwa Ng , Akira R. Kinjo

Active soft bodies can affect their shape through an internal actuation mechanism that induces a deformation. Similar to recent work, this paper utilizes a differentiable, quasi-static, and physics-based simulation layer to optimize for…

Computer Vision and Pattern Recognition · Computer Science 2024-01-29 Lingchen Yang , Byungsoo Kim , Gaspard Zoss , Baran Gözcü , Markus Gross , Barbara Solenthaler

Neuro-fuzzy networks (NFNs) are transparent, symbolic, and universal function approximations that perform as well as conventional neural architectures, but their knowledge is expressed as linguistic IF-THEN rules. Despite these advantages,…

Machine Learning · Computer Science 2026-01-26 John Wesley Hostetter , Min Chi

Neuroscientists fit morphologically and biophysically detailed neuron simulations to physiological data, often using evolutionary algorithms. However, such gradient-free approaches are computationally expensive, making convergence slow when…

Neurons and Cognition · Quantitative Biology 2024-07-23 Ilenna Simone Jones , Konrad Paul Kording

With an ever-growing number of parameters defining increasingly complex networks, Deep Learning has led to several breakthroughs surpassing human performance. As a result, data movement for these millions of model parameters causes a…

Neural and Evolutionary Computing · Computer Science 2023-04-12 Christopher Wolters , Brady Taylor , Edward Hanson , Xiaoxuan Yang , Ulf Schlichtmann , Yiran Chen

The ability to learn continuously from an incoming data stream without catastrophic forgetting is critical for designing intelligent systems. Many existing approaches to continual learning rely on stochastic gradient descent and its…

Machine Learning · Computer Science 2021-03-16 Sandeep Madireddy , Angel Yanguas-Gil , Prasanna Balaprakash

The brain is believed to operate in part by making predictions about sensory stimuli and encoding deviations from these predictions in the activity of "prediction error neurons." This principle defines the widely influential theory of…

Neurons and Cognition · Quantitative Biology 2022-02-21 Vicky Zhu , Robert Rosenbaum

Data-driven dynamic models of cell biology can be used to predict cell response to unseen perturbations. Recent work (CellBox) had demonstrated the derivation of interpretable models with explicit interaction terms, in which the parameters…

Molecular Networks · Quantitative Biology 2021-04-15 Weiqi Ji , Bo Yuan , Ciyue Shen , Aviv Regev , Chris Sander , Sili Deng

New technologies for recording the activity of large neural populations during complex behavior provide exciting opportunities for investigating the neural computations that underlie perception, cognition, and decision-making. Nonlinear…

Machine Learning · Statistics 2020-06-30 Yuan Zhao , Il Memming Park

Brain-inspired machine intelligence research seeks to develop computational models that emulate the information processing and adaptability that distinguishes biological systems of neurons. This has led to the development of spiking neural…

Neural and Evolutionary Computing · Computer Science 2024-10-28 Alexander Ororbia

Big science initiatives are trying to reconstruct and model the brain by attempting to simulate brain tissue at larger scales and with increasingly more biological detail than previously thought possible. The exponential growth of parallel…

Performance · Computer Science 2020-06-25 Francesco Cremonesi , Georg Hager , Gerhard Wellein , Felix Schürmann

Representation learning algorithms offer the opportunity to learn invariant representations of the input data with regard to nuisance factors. Many authors have leveraged such strategies to learn fair representations, i.e., vectors where…

Machine Learning · Computer Science 2025-07-16 Mattia Cerrato , Marius Köppel , Roberto Esposito , Stefan Kramer

To make sense of the world our brains must analyze high-dimensional datasets streamed by our sensory organs. Because such analysis begins with dimensionality reduction, modelling early sensory processing requires biologically plausible…

Neurons and Cognition · Quantitative Biology 2016-01-27 Cengiz Pehlevan , Dmitri B. Chklovskii

A meta-model of the input-output data of a computationally expensive simulation is often employed for prediction, optimization, or sensitivity analysis purposes. Fitting is enabled by a designed experiment, and for computationally expensive…

Methodology · Statistics 2023-12-01 Andrew Gill , David J. Warne , Antony M. Overstall , Clare McGrory , James M. McGree

This paper introduces Stress-Aware Learning, a resilient neural training paradigm in which deep neural networks dynamically adjust their optimization behavior - whether under stable training regimes or in settings with uncertain dynamics -…

Machine Learning · Computer Science 2025-08-04 Ashkan Shakarami , Yousef Yeganeh , Azade Farshad , Lorenzo Nicole , Stefano Ghidoni , Nassir Navab

This paper introduces a biomathematical model designed to describe the internal dynamics of dream formation and spontaneous cognitive processes. The model incorporates neurocognitive factors such as dissatisfaction, acceptance, forgetting,…

Neurons and Cognition · Quantitative Biology 2025-05-12 Shirmohammad Tavangari , Sajjad Janfaza , Zahra Shakarami , Aref Yelghi

Understanding the activity of large populations of neurons is difficult due to the combinatorial complexity of possible cell-cell interactions. To reduce the complexity, coarse-graining had been previously applied to experimental neural…

Neurons and Cognition · Quantitative Biology 2021-03-24 Mia C. Morrell , Audrey J. Sederberg , Ilya Nemenman

Foundation models have shown remarkable success in fitting biological visual systems; however, their black-box nature inherently limits their utility for understanding brain function. Here, we peek inside a SOTA foundation model of neural…

Neurons and Cognition · Quantitative Biology 2026-01-30 Johannes Bertram , Luciano Dyballa , Anderson Keller , Savik Kinger , Steven W. Zucker

Understanding the relationship between large-scale structural and functional brain networks remains a crucial issue in modern neuroscience. Recently, there has been growing interest in investigating the role of homeostatic plasticity…

Neurons and Cognition · Quantitative Biology 2018-10-25 Rodrigo P. Rocha , Loren Koçillari , Samir Suweis , Maurizio Corbetta , Amos Maritan

Neural development represents not only an exciting and complex field of study, with ongoing progress, but it also became the epicentre of neuroscience and developmental biology, as it strives to describe the underlying cellular and…

Neurons and Cognition · Quantitative Biology 2014-05-15 Ana M. Mihut , Graham Morgan , Marcus Kaiser