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A persistent challenge in machine learning for scientific applications is jointly achieving prediction and understanding. Statistical models excel on structured data but operate as black boxes, while existing interpretability methods are…

Machine Learning · Computer Science 2026-05-25 Mohammad R. Rezaei , Rahul G. Krishnan

Recent advancements in medical Large Language Models (LLMs) have showcased their powerful reasoning and diagnostic capabilities. Despite their success, current unified multimodal medical LLMs face limitations in knowledge update costs,…

Computation and Language · Computer Science 2025-06-25 Yucheng Zhou , Lingran Song , Jianbing Shen

Dermatological diagnosis requires integrating fine-grained visual perception with expert clinical knowledge. Although Multimodal Large Language Models (MLLMs) facilitate interactive medical image analysis, their application in dermatology…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Yize Liu , Siyuan Yan , Ming Hu , Lie Ju , Xieji Li , Feilong Tang , Wei Feng , Zongyuan Ge

Recommender models excel at providing domain-specific item recommendations by leveraging extensive user behavior data. Despite their ability to act as lightweight domain experts, they struggle to perform versatile tasks such as providing…

Information Retrieval · Computer Science 2024-01-31 Xu Huang , Jianxun Lian , Yuxuan Lei , Jing Yao , Defu Lian , Xing Xie

Conducting literature reviews for scientific papers is essential for understanding research, its limitations, and building on existing work. It is a tedious task which makes an automatic literature review generator appealing. Unfortunately,…

Large language model (LLM)-based multi-agent systems have demonstrated impressive capabilities in handling complex tasks. However, the complexity of agentic behaviors makes these systems difficult to understand. When failures occur,…

Human-Computer Interaction · Computer Science 2026-02-06 Rui Sheng , Yukun Yang , Chuhan Shi , Yanna Lin , Zixin Chen , Huamin Qu , Furui Cheng

Large language models (LLMs) serve as an active and promising field of generative artificial intelligence and have demonstrated abilities to perform complex tasks in multiple domains, including mathematical and scientific reasoning. In this…

Artificial Intelligence · Computer Science 2026-03-03 Ao Cheng , Lei Zhang , Guowei He

Creating end-to-end bioinformatics workflows requires diverse domain expertise, which poses challenges for both junior and senior researchers as it demands a deep understanding of both genomics concepts and computational techniques. While…

Large Language Models (LLMs) generalize well across language tasks, but suffer from hallucinations and uninterpretability, making it difficult to assess their accuracy without ground-truth. Retrieval-Augmented Generation (RAG) models have…

Computation and Language · Computer Science 2023-12-18 Jakub Lála , Odhran O'Donoghue , Aleksandar Shtedritski , Sam Cox , Samuel G. Rodriques , Andrew D. White

Large language model (LLM) agents are increasingly employing retrieval-augmented generation (RAG) to improve the factuality of their responses. However, in practice, these systems often need to handle ambiguous user queries and potentially…

Computation and Language · Computer Science 2025-08-13 Han Wang , Archiki Prasad , Elias Stengel-Eskin , Mohit Bansal

Recently, Large Language Model (LLM)-empowered recommender systems have revolutionized personalized recommendation frameworks and attracted extensive attention. Despite the remarkable success, existing LLM-empowered RecSys have been…

Information Retrieval · Computer Science 2025-04-04 Liangbo Ning , Wenqi Fan , Qing Li

People commonly leverage structured content to accelerate knowledge acquisition and research problem solving. Among these, roadmaps guide researchers through hierarchical subtasks to solve complex research problems step by step. Despite…

Computation and Language · Computer Science 2026-05-01 Jiacheng Liu , Zichen Tang , Zhongjun Yang , Xinyi Hu , Xueyuan Lin , Linwei Jia , Ruofei Bai , Rongjin Li , Shiyao Peng , Haocheng Gao , Haihong E

LLM agents are rapidly becoming the practical interface for task automation, yet the ecosystem lacks a principled way to choose among an exploding space of deployable configurations. Existing LLM leaderboards and tool/agent benchmarks…

Artificial Intelligence · Computer Science 2026-03-05 Yunxiao Shi , Wujiang Xu , Tingwei Chen , Haoning Shang , Ling Yang , Yunfeng Wan , Zhuo Cao , Xing Zi , Dimitris N. Metaxas , Min Xu

Context: Manual qualitative data analysis is time-intensive and can compromise validity and replicability, affecting analysis design, implementation, and reporting. Large Language Models (LLMs) enable human-bot collaboration in Software…

Software Engineering · Computer Science 2025-10-14 Zeeshan Rasheed , Muhammad Waseem , Aakash Ahmad , Kai-Kristian Kemell , Wang Xiaofeng , Anh Nguyen Duc , Pekka Abrahamsson

Owing to powerful natural language processing and generative capabilities, large language model (LLM) agents have emerged as a promising solution for enhancing recommendation systems via user simulation. However, in the realm of video…

Multimedia · Computer Science 2025-07-04 Siran Chen , Boyu Chen , Chenyun Yu , Yuxiao Luo , Ouyang Yi , Lei Cheng , Chengxiang Zhuo , Zang Li , Yali Wang

Large Language Model (LLM)-based agents have demonstrated strong capabilities across a wide range of tasks, and their application in the medical domain holds particular promise due to the demand for high generalizability and reliance on…

Artificial Intelligence · Computer Science 2025-08-18 Yangyang Zhuang , Wenjia Jiang , Jiayu Zhang , Ze Yang , Joey Tianyi Zhou , Chi Zhang

Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields. While Retrieval-Augmented Generation…

Computation and Language · Computer Science 2026-03-25 Wenhao Wu , Zhentao Tang , Yafu Li , Shixiong Kai , Mingxuan Yuan , Chunlin Chen , Zhi Wang

Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang

Large Language Model (LLM)-based agentic systems have shown growing promise in tackling complex, multi-step tasks through autonomous planning, reasoning, and interaction with external environments. However, the stochastic nature of LLM…

Human-Computer Interaction · Computer Science 2026-03-31 Shuo Yan , Xiaolin Wen , Shaolun Ruan , Yanjie Zhang , Jiaming Mi , Yushi Sun , Huamin Qu , Rui Sheng

Large Language Models (LLMs) have revolutionized AI-generated content evaluation, with the LLM-as-a-Judge paradigm becoming increasingly popular. However, current single-LLM evaluation approaches face significant challenges, including…

Artificial Intelligence · Computer Science 2026-03-03 Yiyue Qian , Shinan Zhang , Yun Zhou , Haibo Ding , Diego Socolinsky , Yi Zhang