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Related papers: HiCat: A Semi-Supervised Approach for Cell Type An…

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Categorizing documents into a given label hierarchy is intuitively appealing due to the ubiquity of hierarchical topic structures in massive text corpora. Although related studies have achieved satisfying performance in fully supervised…

Computation and Language · Computer Science 2023-10-24 Yu Zhang , Xiusi Chen , Yu Meng , Jiawei Han

Accurate and scalable cell type annotation remains a challenge in single-cell transcriptomics, especially when datasets exhibit strong batch effects or contain previously unseen cell populations. Here we introduce SpikGPT, a hybrid deep…

Quantitative Methods · Quantitative Biology 2025-12-04 Min Huang , Rishikesan Kamaleswaran

Identifying cell types and subtypes in routine histopathology is fundamental for understanding disease. Existing tile-based models capture nuclear detail but miss the broader tissue context that influences cell identity. Current human…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Yinuo Xu , Yan Cui , Mingyao Li , Zhi Huang

Fine-grained Entity Typing is a tough task which suffers from noise samples extracted from distant supervision. Thousands of manually annotated samples can achieve greater performance than millions of samples generated by the previous…

Artificial Intelligence · Computer Science 2019-06-14 Sheng Lin , Luye Zheng , Bo Chen , Siliang Tang , Yueting Zhuang , Fei Wu , Zhigang Chen , Guoping Hu , Xiang Ren

Advancements in clinical treatment are increasingly constrained by the limitations of supervised learning techniques, which depend heavily on large volumes of annotated data. The annotation process is not only costly but also demands…

Computer Vision and Pattern Recognition · Computer Science 2024-05-20 Pranav Singh , Raviteja Chukkapalli , Shravan Chaudhari , Luoyao Chen , Mei Chen , Jinqian Pan , Craig Smuda , Jacopo Cirrone

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Biomedical documents such as Electronic Health Records (EHRs) contain a large amount of information in an unstructured format. The data in EHRs is a hugely valuable resource documenting clinical narratives and decisions, but whilst the text…

Computation and Language · Computer Science 2019-12-24 Zeljko Kraljevic , Daniel Bean , Aurelie Mascio , Lukasz Roguski , Amos Folarin , Angus Roberts , Rebecca Bendayan , Richard Dobson

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

As research interests in medical image analysis become increasingly fine-grained, the cost for extensive annotation also rises. One feasible way to reduce the cost is to annotate with coarse-grained superclass labels while using limited…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Linrui Dai , Wenhui Lei , Xiaofan Zhang

Although data is abundant, data labeling is expensive. Semi-supervised learning methods combine a few labeled samples with a large corpus of unlabeled data to effectively train models. This paper introduces our proposed method LiDAM, a…

Machine Learning · Computer Science 2020-11-25 Qun Liu , Matthew Shreve , Raja Bala

In this paper, we introduce a new model for leveraging unlabeled data to improve generalization performances of image classifiers: a two-branch encoder-decoder architecture called HybridNet. The first branch receives supervision signal and…

Machine Learning · Computer Science 2018-07-31 Thomas Robert , Nicolas Thome , Matthieu Cord

Automated single-cell annotation is difficult when the most abundant genes are not the most discriminative ones, or when a target state is poorly covered by a fixed reference atlas. GPTCelltype-style one-shot prompting allows large language…

Quantitative Methods · Quantitative Biology 2026-05-08 Yehui Yang , Zelin Zang , Xienan Zheng , Yuzhe Jia , Changxi Chi , Jingbo Zhou , Chang Yu , Jinlin Wu , Fuji Yang , Jiebo Luo , Zhen Lei , Stan Z. Li

Semi-supervised learning approaches have emerged as an active area of research to combat the challenge of obtaining large amounts of annotated data. Towards the goal of improving the performance of semi-supervised learning methods, we…

Computer Vision and Pattern Recognition · Computer Science 2021-12-22 Ashima Garg , Shaurya Bagga , Yashvardhan Singh , Saket Anand

Semi-supervised learning is a challenging problem which aims to construct a model by learning from a limited number of labeled examples. Numerous methods have been proposed to tackle this problem, with most focusing on utilizing the…

Computer Vision and Pattern Recognition · Computer Science 2021-07-02 Peng Tu , Yawen Huang , Rongrong Ji , Feng Zheng , Ling Shao

In semi-supervised learning, methods that rely on confidence learning to generate pseudo-labels have been widely proposed. However, increasing research finds that when faced with noisy and biased data, the model's representation network is…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Yanbiao Ma , Licheng Jiao , Fang Liu , Lingling Li , Shuyuan Yang , Xu Liu

Reliability in cell type annotation is challenging in single-cell RNA-sequencing data analysis because both expert-driven and automated methods can be biased or constrained by their training data, especially for novel or rare cell types.…

Quantitative Methods · Quantitative Biology 2024-09-25 Wenjin Ye , Yuanchen Ma , Junkai Xiang , Hongjie Liang , Tao Wang , Qiuling Xiang , Andy Peng Xiang , Wu Song , Weiqiang Li , Weijun Huang

Transformer-based models have significantly advanced natural language processing and computer vision in recent years. However, due to the irregular and disordered structure of point cloud data, transformer-based models for 3D deep learning…

Computer Vision and Pattern Recognition · Computer Science 2023-04-07 Xincheng Yang , Mingze Jin , Weiji He , Qian Chen

Semi-supervised techniques have removed the barriers of large scale labelled set by exploiting unlabelled data to improve the performance of a model. In this paper, we propose a semi-supervised deep multi-task classification and…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 R. M. Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot

Modern optical microscopes are fully motorised; however, transforming them into truly smart systems requires real-time adjustment of acquisition settings in response to detected objects and dynamic biological events. At the core are…

Single-cell RNA-seq (scRNA-seq) enables atlas-scale profiling of complex tissues, revealing rare lineages and transient states. Yet, assigning biologically valid cell identities remains a bottleneck because markers are tissue- and…

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