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In this study, we developed an Evidence-based Ensemble Neural Network, namely EVENet, for anatomical brain parcellation using diffusion MRI. The key innovation of EVENet is the design of an evidential deep learning framework to quantify…

Accurate medical image segmentation is crucial for precise anatomical delineation. Deep learning models like U-Net have shown great success but depend heavily on large datasets and struggle with domain shifts, complex structures, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Hantao Zhang , Yuhe Liu , Jiancheng Yang , Weidong Guo , Xinyuan Wang , Pascal Fua

We performed a PubMed search to find 148 papers published between January 2010 and December 2019 related to human brain, Diffusion Tensor Imaging (DTI), and Machine Learning (ML). The studies focused on healthy cohorts (n = 15), mental…

Machine Learning · Computer Science 2020-12-22 Ashirbani Saha , Pantea Fadaiefard , Jessica E. Rabski , Alireza Sadeghian , Michael D. Cusimano

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections at macro scale. Over the last two decades, the study of brain connectivity using…

Quantitative Methods · Quantitative Biology 2021-04-26 Fan Zhang , Alessandro Daducci , Yong He , Simona Schiavi , Caio Seguin , Robert Smith , Chun-Hung Yeh , Tengda Zhao , Lauren J. O'Donnell

High angular resolution diffusion imaging (HARDI) is a type of diffusion magnetic resonance imaging (dMRI) that measures diffusion signals on a sphere in q-space. It has been widely used in data acquisition for human brain structural…

Applications · Statistics 2021-11-12 William Consagra , Arun Venkataraman , Zhengwu Zhang

Diffusion models have recently emerged as powerful priors for solving inverse problems. While computed tomography (CT) is theoretically a linear inverse problem, it poses many practical challenges. These include correlated noise, artifact…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Jiayang Shi , Daniel M. Pelt , K. Joost Batenburg

Quantitative MRI (qMRI) offers significant advantages over weighted images by providing objective parameters related to tissue properties. Deep learning-based methods have demonstrated effectiveness in estimating quantitative maps from…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Shishuai Wang , Hua Ma , Juan A. Hernandez-Tamames , Stefan Klein , Dirk H. J. Poot

Diffusion-weighted magnetic resonance imaging (DW-MRI) can be used to characterise the microstructure of the nervous tissue, e.g. to delineate brain white matter connections in a non-invasive manner via fibre tracking. Magnetic Resonance…

Reconstructing visual stimuli from human brain activities provides a promising opportunity to advance our understanding of the brain's visual system and its connection with computer vision models. Although deep generative models have been…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Jingyuan Sun , Mingxiao Li , Marie-Francine Moens

Diffusion-weighted Magnetic Resonance Imaging (dMRI) is increasingly used to study the fetal brain in utero. An important computation enabled by dMRI is streamline tractography, which has unique applications such as tract-specific analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Camilo Calixto , Camilo Jaimes , Matheus D. Soldatelli , Simon K. Warfield , Ali Gholipour , Davood Karimi

The brain white matter consists of a set of tracts that connect distinct regions of the brain. Segmentation of these tracts is often needed for clinical and research studies. Diffusion-weighted MRI offers unique contrast to delineate these…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Hamza Kebiri , Ali Gholipour , Meritxell Bach Cuadra , Davood Karimi

Diffusion MRI measures of the human brain provide key insight into microstructural variations across individuals and into the impact of central nervous system diseases and disorders. One approach to extract information from diffusion…

Medical Physics · Physics 2022-01-19 Qianqian Yang , David C. Reutens , Viktor Vegh

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

Current fMRI foundation models primarily rely on a limited range of brain states and mismatched pretraining tasks, restricting their ability to learn generalized representations across diverse brain states. We present \textit{Brain-DiT}, a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Junfeng Xia , Wenhao Ye , Xuanye Pan , Xinke Shen , Mo Wang , Quanying Liu

Effective connectivity estimation plays a crucial role in understanding the interactions and information flow between different brain regions. However, the functional time series used for estimating effective connectivity is derived from…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Qiankun Zuo , Ling Chen , Yanyan Shen , Michael Kwok-Po Ng , Baiying Lei , Shuqiang Wang

Diffusion-weighted MRI is the forerunner of the rapidly developed microstructural MRI aimed at in vivo evaluation of the cellular tissue architecture. This brief review focuses on the spatiotemporal scales of the microstructure that are…

Medical Physics · Physics 2020-08-14 Valerij G. Kiselev

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a critical imaging method for capturing and modeling tissue microarchitecture at a millimeter scale. A common practice to model the measured DW-MRI signal is via fiber orientation…

Diffusion tensor imaging (DTI) is a widely used method for studying brain white matter development and degeneration. However, standard DTI estimation methods depend on a large number of high-quality measurements. This would require long…

Image and Video Processing · Electrical Eng. & Systems 2022-11-16 Davood Karimi , Ali Gholipour

Recently, diffusion models have gained significant attention as a novel set of deep learning-based generative methods. These models attempt to sample data from a Gaussian distribution that adheres to a target distribution, and have been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Chenyan Zhang , Yifei Chen , Zhenxiong Fan , Yiyu Huang , Wenchao Weng , Ruiquan Ge , Dong Zeng , Changmiao Wang

Biophysical modeling of diffusion MRI (dMRI) offers the exciting potential of bridging the gap between the macroscopic MRI resolution and microscopic cellular features, effectively turning the MRI scanner into a noninvasive in vivo…