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We study an individual-based stochastic spatial epidemic model where the number of locations and the number of individuals at each location both grow to infinity. Each individual is associated with a random infection-age dependent…

Probability · Mathematics 2025-10-21 Guodong Pang , Etienne Pardoux

Stochastic epidemic models which incorporate interactions between space and human mobility are a key tool to inform prioritisation of outbreak control to appropriate locations. However, methods for fitting such models to national-level…

With the covid-19 pandemic still ongoing and an enormous amount of test data available, the lessons learned over the last two years need to be developed to a point where they can provide understanding for tackling new variants and future…

Populations and Evolution · Quantitative Biology 2022-06-09 Adam Mielke

Health-policy planning requires evidence on the burden that epidemics place on healthcare systems. Multiple, often dependent, datasets provide a noisy and fragmented signal from the unobserved epidemic process including transmission and…

Applications · Statistics 2024-09-11 Alice Corbella , Anne M Presanis , Paul J Birrell , Daniela De Angelis

Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…

Methodology · Statistics 2022-11-29 Jenny Huang , Raphaël Morsomme , David Dunson , Jason Xu

The basic reproduction number, $R_0$, is a well-known quantifier of epidemic spread. However, a class of existing methods for estimating $R_0$ from incidence data early in the epidemic can lead to an over-estimation of this quantity. In…

Populations and Evolution · Quantitative Biology 2024-03-27 Wajid Ali , Christopher E. Overton , Robert R. Wilkinson , Kieran J. Sharkey

We consider the problem of estimating the topology of spatial interactions in a discrete state, discrete time spatio-temporal graphical model where the interactions affect the temporal evolution of each agent in a network. Among other…

Machine Learning · Statistics 2010-04-15 Patrick L. Harrington , Alfred O. Hero

Since 1927, until recently, models describing the spread of disease have mostly been of the SIR-compartmental type, based on the assumption that populations are homogeneous and well-mixed. The focus of these models have typically been on…

Physics and Society · Physics 2014-07-23 Lara Goscé , David A W Barton , Anders Johansson

We generalize the well known formulation of the susceptibles, infected, susceptibles (SIS) spatial epidemics with creation and annihilation operators to the reinfection model including recovered which can be reinfected, the SIRI model,…

Statistical Mechanics · Physics 2008-06-30 Nico Stollenwerk , Maira Aguiar

We propose a Markovian stochastic approach to model the spread of a SARS-CoV-2-like infection within a closed group of humans. The model takes the form of a Partially Observable Markov Decision Process (POMDP), whose states are given by the…

Systems and Control · Electrical Eng. & Systems 2022-04-26 Luigi Palopoli , Daniele Fontanelli , Marco Frego , Marco Roveri

We consider a time-inhomogeneous diffusion process able to describe the dynamics of infected people in a susceptible-infectious epidemic model in which the transmission intensity function is time-dependent. Such a model is well suited to…

Methodology · Statistics 2024-10-30 Giuseppina Albano , Virginia Giorno , Francisco Torres-Ruiz

Epidemic threshold is one of the most important features of the epidemic dynamics. Through a lot of numerical simulations in classic Susceptible-Infected-Recovered (SIR) and Susceptible-Infected-Susceptible (SIS) models on various types of…

Physics and Society · Physics 2014-10-16 Panpan Shu , Wei Wang , Ming Tang , Younghae Do

Exploiting the power of the expectation operator and indicator (or Bernoulli) random variables, we present the exact governing equations for both the SIR and SIS epidemic models on \emph{networks}. Although SIR and SIS are basic epidemic…

Dynamical Systems · Mathematics 2014-02-10 Piet Van Mieghem

Global pandemics, such as the recent COVID-19 crisis, highlight the need for stochastic epidemic models that can capture the randomness inherent in the spread of disease. Such models must be accompanied by methods for estimating parameters…

Quantitative Methods · Quantitative Biology 2026-04-13 Vincent Wieland , Nils Wassmuth , Lorenzo Contento , Martin Kühn , Jan Hasenauer

Predicting Pandemic evolution involves complex modeling challenges, often requiring detailed discrete mathematics executed on large volumes of epidemiological data. Differential equations have the advantage of offering smooth, well-behaved…

Biological Physics · Physics 2023-02-28 Clara Bender , Abhimanyu Ghosh , Hamed Vakili , Preetam Ghosh , Avik W. Ghosh

We study a coupled epidemic-mobility model in which, at each time, individuals move in a network of spatially-distributed regions (sub-populations) according to a Continuous Time Markov Chain (CTMC) and subsequently interact with the local…

Systems and Control · Electrical Eng. & Systems 2019-09-30 Vishal Abhishek , Vaibhav Srivastava

In this work we review a class of deterministic nonlinear models for the propagation of infectious diseases over contact networks with strongly-connected topologies. We consider network models for susceptible-infected (SI),…

Social and Information Networks · Computer Science 2017-01-13 Wenjun Mei , Shadi Mohagheghi , Sandro Zampieri , Francesco Bullo

We exhibit a stochastic discrete time model that has exactly the Eigen model as its deterministic continuous limit. Such model can be divided into two phases: reproduction followed by neutral selection. This result suggests that Eigen model…

Populations and Evolution · Quantitative Biology 2011-02-03 Fabio Musso

This paper is concerned with a stochastic model for the spread of an SEIR (susceptible -> exposed (=latent) -> infective -> removed) epidemic with a contact tracing scheme, in which removed individuals may name some of their infectious…

Probability · Mathematics 2015-12-08 Frank G Ball , Edward S Knock , Philip D O'Neill

We consider the emergent behavior of viral spread when agents in a large population interact with each other over a contact network. When the number of agents is large and the contact network is a complete graph, it is well known that the…

Physics and Society · Physics 2021-04-13 Anirudh Sridhar , Soummya Kar
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