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We introduce a general theoretical framework to study the shape dynamics of actively growing and remodeling surfaces. Using this framework we develop a physical model for growing bacterial cell walls and study the interplay of cell shape…

Biological Physics · Physics 2016-04-08 Shiladitya Banerjee , Norbert F. Scherer , Aaron R. Dinner

Cell spreading and motility on an adhesive substrate are driven by the active physical forces generated by the actin cytoskeleton. We have recently shown that coupling curved membrane complexes to protrusive forces, exerted by the actin…

Soft Condensed Matter · Physics 2023-04-04 Shubhadeep Sadhukhan , Samo Penič , Aleš Iglič , Nir Gov

The dynamics of red blood cells (RBCs) in simple shear flow was studied using a theoretical approach based on three variables: a shape parameter, the inclination angle $\theta$, and phase angle $\phi$ of the membrane rotation. At high shear…

Soft Condensed Matter · Physics 2009-08-07 Hiroshi Noguchi

The activity of growing living bacteria was investigated using real-time and in situ rheology -- in stationary and oscillatory shear. Two different strains of the human pathogen Staphylococcus aureus -- strain COL and its isogenic cell wall…

Biological Physics · Physics 2015-06-19 P. Patricio , P. L. Almeida , R. Portela , R. G. Sobral , I. R. Grilo , T. Cidade , C. R. Leal

How motile bacteria move near a surface is a problem of fundamental biophysical interest and is key to the emergence of several phenomena of biological, ecological and medical relevance, including biofilm formation. Solid boundaries can…

Biological Physics · Physics 2019-09-12 Stanislaw Makarchuk , Vasco C. Braz , Nuno A. M. Araújo , Lena Ciric , Giorgio Volpe

Rheotaxis is a well-known phenomenon among microbial organisms and artificial active colloids, wherein the swimmers respond to an imposed flow. We report the first experimental evidence of upstream rheotaxis by spherical active droplets. It…

Soft Condensed Matter · Physics 2021-08-20 Prateek Dwivedi , Atishay Shrivastava , Dipin Pillai , Rahul Mangal

The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the non-migrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in…

Cell Behavior · Quantitative Biology 2016-06-29 Davide Ambrosi , Anna Zanzottera

The effects of cell size and deformability on the lateral migration and deformation of living cells flowing through a rectangular microchannel has been numerically investigated and compared with the inertial-microfluidics data on detection…

Fluid Dynamics · Physics 2013-06-21 Hongzhi Lan , Soojung Claire Hur , Dino Di Carlo , Damir B. Khismatullin

The symmetry breaking of the actin network from radial to longitudinal symmetry has been identified as the major mechanism for keratocytes (fish cells) motility on solid substrate. For strong friction coefficient, the two dimensional actin…

Soft Condensed Matter · Physics 2011-02-16 M. Ben Amar , O. V. Manyuhina , G. Napoli

Many wormlike micellar systems exhibit appreciable shear thinning due to shear induced alignment. As the micelles get aligned introducing directionality in the system, the viscoelastic properties are no longer expected to be isotropic. An…

Soft Condensed Matter · Physics 2011-05-09 Manas Khan , A. K. Sood

Helical-shaped magnetotactic bacteria provide a rare opportunity to precisely measure both the translational and rotational friction coefficients of micron-sized chiral particles. The possibility to align these cells with a uniform magnetic…

Biological Physics · Physics 2022-10-12 Liu Yu , Lucas Le Nagard , Solomon Barkley , Lauren Smith , Cecile Fradin

The dynamics of red blood cells (RBCs) in oscillatory shear flow was studied using differential equations of three variables: a shape parameter, the inclination angle $\theta$, and phase angle $\phi$ of the membrane rotation. In steady…

Soft Condensed Matter · Physics 2010-06-24 Hiroshi Noguchi

Flagellar-driven locomotion plays a critical role in bacterial attachment and colonization of surfaces, contributing to the risks of contamination and infection. Tremendous attempts to uncover the underlying principles governing bacterial…

Soft Condensed Matter · Physics 2025-02-19 Xin-Xin Xu , Yangguang Tian , Yuhe Pu , Bingchen Che , Hao Luo , Yanan Liu , Yan-Jun Liu , Guangyin Jing

During colony growth, complex interactions regulate the bacterial orientation, leading to the formation of large-scale ordered structures, including topological defects and microdomains. These structures may benefit bacterial strains,…

Biological Physics · Physics 2024-04-10 Mustafa Başaran , Y. Ilker Yaman , Tevfik Can Yuce , Roman Vetter , Askin Kocabas

Bacteria have remarkably robust cell shape control mechanisms. For example, cell diameter only varies by a few percent across a population. MreB is necessary for establishment and maintenance of rod shape although the mechanism of shape…

Flagellated bacteria exploiting helical propulsion are known to swim along circular trajectories near surfaces. Fluid dynamics predicts this circular motion to be clockwise (CW) above a rigid surface (when viewed from inside the fluid) and…

Biological Physics · Physics 2014-07-18 Diego Lopez , Eric Lauga

Bacterial chemotaxis is one of the most extensively studied adaptive responses in cells. Many bacteria are able to bias their apparently random motion to produce a drift in the direction of the increasing chemoattractant concentration. It…

Soft Condensed Matter · Physics 2018-02-07 E. V. Pankratova , A. I. Kalyakulina , M. I. Krivonosov , S. Denisov , K. M. Taute , V. Yu. Zaburdaev

Can topography be used to control bacteria accumulation? We address this question in the model system of smooth-swimming and run-and-tumble \textit{Escherichia coli} swimming near a sinusoidal surface, and show that the accumulation of…

Soft Condensed Matter · Physics 2023-08-08 Benjamín Pérez-Estay , María Luisa Cordero , Néstor Sepúlveda , Rodrigo Soto

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

Biological Physics · Physics 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

Bacterial chemotaxis in Escherichia coli is a canonical system for the study of signal transduction. A remarkable feature of this system is the coexistence of precise adaptation in population with large fluctuating cellular behavior in…

Molecular Networks · Quantitative Biology 2019-08-19 Thierry Emonet , Philippe Cluzel