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The main objective of eXplainable Artificial Intelligence (XAI) is to provide effective explanations for black-box classifiers. The existing literature lists many desirable properties for explanations to be useful, but there is no consensus…

Artificial Intelligence · Computer Science 2021-06-02 Elvio G. Amparore , Alan Perotti , Paolo Bajardi

Explaining deep learning models is essential for clinical integration of medical image analysis systems. A good explanation highlights if a model depends on spurious features that undermines generalization and harms a subset of patients or,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Yoni Schirris , Eric Marcus , Jonas Teuwen , Hugo Horlings , Efstratios Gavves

Development processes in various engineering disciplines are incorporating formal models to ensure safety properties of critical systems. The use of these formal models requires to reason about their adequacy, i.e., to validate that a model…

Human-Computer Interaction · Computer Science 2019-12-24 Eduard Kamburjan , Jonas Stromberg

The significant features identified in a representative subset of the dataset during the learning process of an artificial intelligence model are referred to as a 'global' explanation. 3D global explanations are crucial in neuroimaging,…

Molecular dynamics (MD) simulations have become popular in materials science, biochemistry, biophysics and several other fields. Improvements in computational resources, in quality of force field parameters and algorithms have yielded…

Soft Condensed Matter · Physics 2016-11-28 Jirasak Wong-ekkabut , Mikko Karttunen

As AI systems enter into a growing number of societal domains, these systems increasingly shape and are shaped by user preferences, opinions, and behaviors. However, the design of AI systems rarely accounts for how AI and users shape one…

Machine Learning · Computer Science 2024-04-19 Sarah Dean , Evan Dong , Meena Jagadeesan , Liu Leqi

The use of Artificial Intelligence (AI) models in real-world and high-risk applications has intensified the discussion about their trustworthiness and ethical usage, from both a technical and a legislative perspective. The field of…

Machine Learning · Computer Science 2025-12-17 Ilaria Vascotto , Alex Rodriguez , Alessandro Bonaita , Luca Bortolussi

3D objects (artefacts) are made to fulfill functions. Designing an object often starts with defining a list of functionalities that it should provide, also known as functional requirements. Today, the design of 3D object models is still a…

Artificial Intelligence · Computer Science 2018-10-18 Mihai Andries , Atabak Dehban , José Santos-Victor

Simulations with high accuracy are an essential part of scientific research to accelerate the innovation process. They are especially useful for finding novel approaches or optimizing existing methods. Today, powerful software tools are…

Medical Physics · Physics 2022-08-31 Patrick Vogel , Martin A. Rückert , Thomas Kampf , Volker C. Behr

Trustworthy interpretation of deep learning models is critical for neuroimaging applications, yet commonly used Explainable AI (XAI) methods lack rigorous validation, risking misinterpretation. We performed the first large-scale, systematic…

Machine Learning · Computer Science 2025-08-07 Nys Tjade Siegel , James H. Cole , Mohamad Habes , Stefan Haufe , Kerstin Ritter , Marc-André Schulz

Recent legislative regulations have underlined the need for accountable and transparent artificial intelligence systems and have contributed to a growing interest in the Explainable Artificial Intelligence (XAI) field. Nonetheless, the lack…

Machine Learning · Computer Science 2025-10-14 Ilaria Vascotto , Alex Rodriguez , Alessandro Bonaita , Luca Bortolussi

Soft X-ray tomography provides detailed structural insight into whole cells but is hindered by experimental artifacts such as the missing wedge and by limited availability of annotated datasets. We present SimAQ, a simulation pipeline that…

Quantitative Methods · Quantitative Biology 2026-05-21 Jacob Egebjerg , Daniel Wüstner

Graph and network visualization supports exploration, analysis and communication of relational data arising in many domains: from biological and social networks, to transportation and powergrid systems. With the arrival of AI-based…

Purpose: Conventional MRI is relying on the assumption of the magnetic field being homogeneous in direction and amplitude. However, with the growing interest in portable, affordable point-of-care MRI systems, these assumptions do not…

Medical Physics · Physics 2026-02-17 Fabian Bschorr , Thomas Hüfken , Tobias Lobmeyer , Volker Rasche

According to a mainstream position in contemporary cognitive science and philosophy, the use of abstract compositional concepts is both a necessary and a sufficient condition for the presence of genuine thought. In this article, we show how…

Machine Learning · Computer Science 2019-10-17 Katja Ried , Benjamin Eva , Thomas Müller , Hans J. Briegel

Nowadays Artificial Intelligence (AI) has become a fundamental component of healthcare applications, both clinical and remote, but the best performing AI systems are often too complex to be self-explaining. Explainable AI (XAI) techniques…

Machine Learning · Computer Science 2022-09-15 Flavio Di Martino , Franca Delmastro

Explainable AI (XAI) is widely viewed as a sine qua non for ever-expanding AI research. A better understanding of the needs of XAI users, as well as human-centered evaluations of explainable models are both a necessity and a challenge. In…

Artificial Intelligence · Computer Science 2024-10-17 Yao Rong , Tobias Leemann , Thai-trang Nguyen , Lisa Fiedler , Peizhu Qian , Vaibhav Unhelkar , Tina Seidel , Gjergji Kasneci , Enkelejda Kasneci

After a rapid introduction about the models of comptonization, we present some simulations that underlines the expected capabilities of Simbol-X to constrain the presence of this process in objects like AGNs or XRB.

Astrophysics · Physics 2008-02-07 Pierre-Olivier Petrucci

State of the art Artificial Intelligence (AI) techniques have reached an impressive complexity. Consequently, researchers are discovering more and more methods to use them in real-world applications. However, the complexity of such systems…

Artificial Intelligence · Computer Science 2021-11-08 Marco Matarese , Francesco Rea , Alessandra Sciutti

Geometric modeling by constraints, whose applications are of interest to communities from various fields such as mechanical engineering, computer aided design, symbolic computation or molecular chemistry, is now integrated into standard…

Computational Geometry · Computer Science 2018-03-06 Samy Ait-Aoudia , Adel Moussaoui , Khaled Abid , Dominique Michelucci