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The classification of histopathological images is of great value in both cancer diagnosis and pathological studies. However, multiple reasons, such as variations caused by magnification factors and class imbalance, make it a challenging…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Yibao Sun , Xingru Huang , Yaqi Wang , Huiyu Zhou , Qianni Zhang

Echocardiography (echo) is the first imaging modality used when assessing cardiac function. The measurement of functional biomarkers from echo relies upon the segmentation of cardiac structures and deep learning models have been proposed to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Iman Islam , Esther Puyol-Antón , Bram Ruijsink , Andrew J. Reader , Andrew P. King

Clustering continues to be a significant and challenging task. Recent studies have demonstrated impressive results by applying clustering to feature representations acquired through self-supervised learning, particularly on small datasets.…

Machine Learning · Computer Science 2023-07-19 Fei Ding , Dan Zhang , Yin Yang , Venkat Krovi , Feng Luo

Data imbalance is a well-known issue in the field of machine learning, attributable to the cost of data collection, the difficulty of labeling, and the geographical distribution of the data. In computer vision, bias in data distribution…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Shubham Shrivastava , Xianling Zhang , Sushruth Nagesh , Armin Parchami

In this paper, we propose a novel method, aggregation cross-entropy (ACE), for sequence recognition from a brand new perspective. The ACE loss function exhibits competitive performance to CTC and the attention mechanism, with much quicker…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Zecheng Xie , Yaoxiong Huang , Yuanzhi Zhu , Lianwen Jin , Yuliang Liu , Lele Xie

Recent advancements in learning algorithms have demonstrated that the sharpness of the loss surface is an effective measure for improving the generalization gap. Building upon this concept, Sharpness-Aware Minimization (SAM) was proposed to…

Machine Learning · Computer Science 2024-06-21 Tanapat Ratchatorn , Masayuki Tanaka

Skin image datasets often suffer from imbalanced data distribution, exacerbating the difficulty of computer-aided skin disease diagnosis. Some recent works exploit supervised contrastive learning (SCL) for this long-tailed challenge.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Yilan Zhang , Jianqi Chen , Ke Wang , Fengying Xie

Medical image data are usually imbalanced across different classes. One-class classification has attracted increasing attention to address the data imbalance problem by distinguishing the samples of the minority class from the majority…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Long Gao , Chang Liu , Dooman Arefan , Ashok Panigrahy , Shandong Wu

In the face of dataset shift, model calibration plays a pivotal role in ensuring the reliability of machine learning systems. Calibration error (CE) is an indicator of the alignment between the predicted probabilities and the classifier…

Machine Learning · Computer Science 2023-12-15 Teodora Popordanoska , Gorjan Radevski , Tinne Tuytelaars , Matthew B. Blaschko

Weakly supervised methods, such as class activation maps (CAM) based, have been applied to achieve bleeding segmentation with low annotation efforts in Wireless Capsule Endoscopy (WCE) images. However, the CAM labels tend to be extremely…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Fan Bai , Xiaohan Xing , Yutian Shen , Han Ma , Max Q. -H. Meng

Deep neural networks (DNNs) have achieved tremendous success in a variety of applications across many disciplines. Yet, their superior performance comes with the expensive cost of requiring correctly annotated large-scale datasets.…

Machine Learning · Computer Science 2018-12-03 Zhilu Zhang , Mert R. Sabuncu

Deep neural networks for medical image segmentation are often overconfident, compromising both reliability and clinical utility. In this work, we propose differentiable formulations of marginal L1 Average Calibration Error (mL1-ACE) as an…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Theodore Barfoot , Luis C. Garcia-Peraza-Herrera , Samet Akcay , Ben Glocker , Tom Vercauteren

Loss reweighting is a widely used strategy for long-tailed classification, but existing reweighting strategies often rely on heuristics and rarely define a well-specified target. Inspired by Neural Collapse (NC), the ideal simplex…

Machine Learning · Computer Science 2026-05-12 Jinping Wang , Zixin Tong , Zhiwu Xie , Zhiqiang Gao

The cross entropy loss is widely used due to its effectiveness and solid theoretical grounding. However, as training progresses, the loss tends to focus on hard to classify samples, which may prevent the network from obtaining gains in…

Machine Learning · Computer Science 2021-09-14 Barak Battash , Lior Wolf , Tamir Hazan

Albeit the Dice loss is one of the dominant loss functions in medical image segmentation, most research omits a closer look at its derivative, i.e. the real motor of the optimization when using gradient descent. In this paper, we highlight…

Computer Vision and Pattern Recognition · Computer Science 2022-11-10 Sofie Tilborghs , Jeroen Bertels , David Robben , Dirk Vandermeulen , Frederik Maes

Deep convolutional neural networks (CNN) have proven to be remarkably effective in semantic segmentation tasks. Most popular loss functions were introduced targeting improved volumetric scores, such as the Dice coefficient (DSC). By design,…

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

Diabetic retinopathy is a leading cause of blindness around the world and demands precise AI-based diagnostic tools. Traditional loss functions in multi-class classification, such as Categorical Cross-Entropy (CCE), are very common but…

Image and Video Processing · Electrical Eng. & Systems 2025-04-24 Santhosh Malarvannan , Pandiyaraju V , Shravan Venkatraman , Abeshek A , Priyadarshini B , Kannan A

Loss functions play a central role in supervised classification. Cross-entropy (CE) is widely used, whereas the mean absolute error (MAE) loss can offer robustness but is difficult to optimize. Interpolating between the CE and MAE losses,…

Machine Learning · Statistics 2026-04-29 Kartheek Bondugula , Santiago Mazuelas , Aritz Pérez , Anqi Liu

End-stage chronic kidney disease (CKD) patients are facing a 30% rise for the risk of lethal cardiac events (LCE) compared to non-CKD patients. At the same time, these patients undergoing dialysis experience shifts in the potassium…

Signal Processing · Electrical Eng. & Systems 2020-06-11 Nicolas Pilia , Cristiana Corsi , Stefano Severi , Olaf Dössel , Axel Loewe
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