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We take up the challenge of designing realistic computational models of large interacting cell populations. The goal is essentially to bring Gillespie's celebrated stochastic methodology to the level of an interacting population of cells.…

Computational Engineering, Finance, and Science · Computer Science 2018-10-26 Stefan Engblom

Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histology parameters. In…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Srijay Deshpande , Muhammad Dawood , Fayyaz Minhas , Nasir Rajpoot

Protein structure prediction and folding are fundamental to understanding biology, with recent deep learning advances reshaping the field. Diffusion-based generative models have revolutionized protein design, enabling the creation of novel…

Machine Learning · Computer Science 2025-10-01 Yogesh Verma , Markus Heinonen , Vikas Garg

Diffusion models have become a new generative paradigm for text generation. Considering the discrete categorical nature of text, in this paper, we propose GlyphDiffusion, a novel diffusion approach for text generation via text-guided image…

Computation and Language · Computer Science 2023-05-09 Junyi Li , Wayne Xin Zhao , Jian-Yun Nie , Ji-Rong Wen

Generative models, especially Diffusion Models, have demonstrated remarkable capability in generating high-quality synthetic data, including medical images. However, traditional class-conditioned generative models often struggle to generate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Nusrat Munia , Abdullah Imran

Acquiring aligned visuo-tactile datasets is slow and costly, requiring specialised hardware and large-scale data collection. Synthetic generation is promising, but prior methods are typically single-modality, limiting cross-modal learning.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Sirine Bhouri , Lan Wei , Jian-Qing Zheng , Dandan Zhang

In computational pathology, understanding and generation have evolved along disparate paths: advanced understanding models already exhibit diagnostic-level competence, whereas generative models largely simulate pixels. Progress remains…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Minghao Han , Yichen Liu , Yizhou Liu , Zizhi Chen , Jingqun Tang , Xuecheng Wu , Dingkang Yang , Lihua Zhang

We present Surf-D, a novel method for generating high-quality 3D shapes as Surfaces with arbitrary topologies using Diffusion models. Previous methods explored shape generation with different representations and they suffer from limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Zhengming Yu , Zhiyang Dou , Xiaoxiao Long , Cheng Lin , Zekun Li , Yuan Liu , Norman Müller , Taku Komura , Marc Habermann , Christian Theobalt , Xin Li , Wenping Wang

Diffusion-based voxel prior modelling is challenging for the reconstruction of large-scale 3D porous microstructures. Due to the demanding requirements for simultaneously modelling both the continuous pore morphology and the discrete…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Yue Shi , Peng Wang , Mingzhe Yu , Yunlong Zhao , Li Liu , Gareth D Hatton , Yan Lyu , Liangxiu Han

This work introduces NetDiff, an expressive graph denoising diffusion probabilistic architecture that generates wireless ad hoc network link topologies. Such networks, with directional antennas, can achieve unmatched performance when the…

Social and Information Networks · Computer Science 2024-10-14 Félix Marcoccia , Cédric Adjih , Paul Mühlethaler

Deep generative models have significantly advanced medical imaging analysis by enhancing dataset size and quality. Beyond mere data augmentation, our research in this paper highlights an additional, significant capacity of deep generative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Xiaodan Xing , Junzhi Ning , Yang Nan , Guang Yang

Graph generative models are essential across diverse scientific domains by capturing complex distributions over relational data. Among them, graph diffusion models achieve superior performance but face inefficient sampling and limited…

Machine Learning · Computer Science 2025-06-17 Yiming Qin , Manuel Madeira , Dorina Thanou , Pascal Frossard

Anatomical atlases are widely used for population studies and analysis. Conditional atlases target a specific sub-population defined via certain conditions, such as demographics or pathologies, and allow for the investigation of…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Sophie Starck , Vasiliki Sideri-Lampretsa , Bernhard Kainz , Martin J. Menten , Tamara T. Mueller , Daniel Rueckert

A long-standing challenge is designing multi-scale structures with good connectivity between cells while optimizing each cell to reach close to the theoretical performance limit. We propose a new method for direct multi-scale topology…

Neural and Evolutionary Computing · Computer Science 2025-02-21 Hongrui Chen , Xingchen Liu , Levent Burak Kara

Recent advances in generative modeling, namely Diffusion models, have revolutionized generative modeling, enabling high-quality image generation tailored to user needs. This paper proposes a framework for the generative design of structural…

Generative models have advanced significantly in realistic image synthesis, with diffusion models excelling in quality and stability. Recent multi-view diffusion models improve 3D-aware street view generation, but they struggle to produce…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Ji Li , Zhiwei Li , Shihao Li , Zhenjiang Yu , Boyang Wang , Haiou Liu

Large-scale generative models have demonstrated impressive capabilities in producing visually compelling images, with increasing applications in medical imaging. However, they continue to grapple with hallucination challenges and the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Anees Ur Rehman Hashmi , Ibrahim Almakky , Mohammad Areeb Qazi , Santosh Sanjeev , Vijay Ram Papineni , Jagalpathy Jagdish , Mohammad Yaqub

Talking head generation is a significant research topic that still faces numerous challenges. Previous works often adopt generative adversarial networks or regression models, which are plagued by generation quality and average facial shape…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Ziyu Yao , Xuxin Cheng , Zhiqi Huang

Deep learning models have emerged as a powerful tool for various medical applications. However, their success depends on large, high-quality datasets that are challenging to obtain due to privacy concerns and costly annotation. Generative…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Milad Yazdani , Yasamin Medghalchi , Pooria Ashrafian , Ilker Hacihaliloglu , Dena Shahriari

Recent advances in synthetic imaging open up opportunities for obtaining additional data in the field of surgical imaging. This data can provide reliable supplements supporting surgical applications and decision-making through computer…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Simeon Allmendinger , Patrick Hemmer , Moritz Queisner , Igor Sauer , Leopold Müller , Johannes Jakubik , Michael Vössing , Niklas Kühl
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