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Medical vision-and-language models (MVLMs) have attracted substantial interest due to their capability to offer a natural language interface for interpreting complex medical data. Their applications are versatile and have the potential to…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Qi Chen , Ruoshan Zhao , Sinuo Wang , Vu Minh Hieu Phan , Anton van den Hengel , Johan Verjans , Zhibin Liao , Minh-Son To , Yong Xia , Jian Chen , Yutong Xie , Qi Wu

Medical Vision-Language Pre-training (VLP) learns representations jointly from medical images and paired radiology reports. It typically requires large-scale paired image-text datasets to achieve effective pre-training for both the image…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Che Liu , Anand Shah , Wenjia Bai , Rossella Arcucci

Multi-modal large language models (MLLMs) have shown promise in advancing healthcare. However, most existing models remain confined to single-image understanding, which greatly limits their applicability in clinical workflows. In practice,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Zhen Chen , Yihang Fu , Gabriel Madera , Mauro Giuffre , Serina Applebaum , Hyunjae Kim , Hua Xu , Qingyu Chen

In this paper, we consider enhancing medical visual-language pre-training (VLP) with domain-specific knowledge, by exploiting the paired image-text reports from the radiological daily practice. In particular, we make the following…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Chaoyi Wu , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Recent progress in vision-language modeling for 3D medical imaging has been fueled by large-scale computed tomography (CT) corpora with paired free-text reports, stronger architectures, and powerful pretrained models. This has enabled…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Ibrahim Ethem Hamamci , Sezgin Er , Suprosanna Shit , Hadrien Reynaud , Dong Yang , Pengfei Guo , Marc Edgar , Daguang Xu , Bernhard Kainz , Bjoern Menze

Multiparametric 3D brain MRI (mpMRI) is central to neuroradiology, but producing tumor location, appearance, size, and involvement of critical structures for neurosurgical planning remains challenging. We introduce mpLLM, a multimodal LLM…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Arvind Murari Vepa , Yannan Yu , Jingru Gan , Anthony Cuturrufo , Michael F. Romano , Weikai Li , Fabien Scalzo , Wei Wang , Yizhou Sun

Accurate disease interpretation from radiology remains challenging due to imaging heterogeneity. Achieving expert-level diagnostic decisions requires integration of subtle image features with clinical knowledge. Yet major vision-language…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Difei Gu , Yunhe Gao , Mu Zhou , Dimitris Metaxas

Self-supervised vision-and-language pretraining (VLP) aims to learn transferable multi-modal representations from large-scale image-text data and to achieve strong performances on a broad scope of vision-language tasks after finetuning.…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Yongfei Liu , Chenfei Wu , Shao-yen Tseng , Vasudev Lal , Xuming He , Nan Duan

Medical vision-language models (Med-VLMs) have shown impressive results in tasks such as report generation and visual question answering, but they still face several limitations. Most notably, they underutilize patient metadata and lack…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Fangqi Cheng , Surajit Ray , Xiaochen Yang

Medical Visual Question Answering (Med-VQA) represents a critical and challenging subtask within the general VQA domain. Despite significant advancements in general VQA, multimodal large language models (MLLMs) still exhibit substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Hongyu Ge , Longkun Hao , Zihui Xu , Zhenxin Lin , Bin Li , Shoujun Zhou , Hongjin Zhao , Yihang Liu

Medical image analysis is crucial in modern radiological diagnostics, especially given the exponential growth in medical imaging data. The demand for automated report generation systems has become increasingly urgent. While prior research…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Hao Chen , Wei Zhao , Yingli Li , Tianyang Zhong , Yisong Wang , Youlan Shang , Lei Guo , Junwei Han , Tianming Liu , Jun Liu , Tuo Zhang

Medical Visual Question Answering (Med-VQA) holds significant potential for clinical decision support, yet existing efforts primarily focus on 2D imaging with limited task diversity. This paper presents 3D-RAD, a large-scale dataset…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Xiaotang Gai , Jiaxiang Liu , Yichen Li , Zijie Meng , Jian Wu , Zuozhu Liu

Recent advancements in Vision Language Models (VLMs) have demonstrated remarkable promise in generating visually grounded responses. However, their application in the medical domain is hindered by unique challenges. For instance, most VLMs…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Lingxiao Luo , Bingda Tang , Xuanzhong Chen , Rong Han , Ting Chen

Visual spatial intelligence is critical for medical image interpretation, yet remains largely unexplored in Multimodal Large Language Models (MLLMs) for 3D imaging. This gap persists due to a systemic lack of datasets featuring structured…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Quoc-Huy Trinh , Xi Ding , Yang Liu , Zhenyue Qin , Xingjian Li , Gorkem Durak , Halil Ertugrul Aktas , Elif Keles , Ulas Bagci , Min Xu

Current medical vision-language models (VLMs) process volumetric brain MRI using 2D slice-based approximations, fragmenting the spatial context required for accurate neuroradiological interpretation. We developed \textbf{Brain3D}, a staged…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Mariano Barone , Francesco Di Serio , Giuseppe Riccio , Antonio Romano , Marco Postiglione , Antonino Ferraro , Vincenzo Moscato

The rapid advancement of Large Multimodal Models (LMMs) for 2D images and videos has motivated extending these models to understand 3D scenes, aiming for human-like visual-spatial intelligence. Nevertheless, achieving deep spatial…

Vision-Language Models (VLMs) are becoming increasingly popular in the medical domain, bridging the gap between medical images and clinical language. Existing VLMs demonstrate an impressive ability to comprehend medical images and text…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Bidur Khanal , Sandesh Pokhrel , Sanjay Bhandari , Ramesh Rana , Nikesh Shrestha , Ram Bahadur Gurung , Cristian Linte , Angus Watson , Yash Raj Shrestha , Binod Bhattarai

The scarcity of annotations poses a significant challenge in medical image analysis. Large-scale pre-training has emerged as a promising label-efficient solution, owing to the utilization of large-scale data, large models, and advanced…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Linshan Wu , Jiaxin Zhuang , Hao Chen

Multi-modal large language models (MLLMs) have made significant strides in various visual understanding tasks. However, the majority of these models are constrained to process low-resolution images, which limits their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Xiangyu Zhao , Xiangtai Li , Haodong Duan , Haian Huang , Yining Li , Kai Chen , Hua Yang