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Unsupervised pre-training approaches have achieved great success in many fields such as Computer Vision (CV), Natural Language Processing (NLP) and so on. However, compared to typical deep learning models, pre-training or even fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2023-02-22 Penghao Jiang , Xuanchen Hou , Yinsi Zhou

In this work, we address two limitations of existing conditional diffusion models: their slow inference speed due to the iterative denoising process and their reliance on paired data for model fine-tuning. To tackle these issues, we…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Gaurav Parmar , Taesung Park , Srinivasa Narasimhan , Jun-Yan Zhu

We propose an efficient approach to train large diffusion models with masked transformers. While masked transformers have been extensively explored for representation learning, their application to generative learning is less explored in…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Hongkai Zheng , Weili Nie , Arash Vahdat , Anima Anandkumar

Three-dimensional molecular generators based on diffusion models can now reach near-crystallographic accuracy, yet they remain fragmented across tasks. SMILES-only inputs, two-stage pretrain-finetune pipelines, and one-task-one-model…

Biomolecules · Quantitative Biology 2025-07-11 Dong Xu , Zhangfan Yang , Sisi Yuan , Jenna Xinyi Yao , Jiangqiang Li , Junkai Ji

This paper's primary objective is to develop a robust generalist perception model capable of addressing multiple tasks under constraints of computational resources and limited training data. We leverage text-to-image diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Canyu Zhao , Yanlong Sun , Mingyu Liu , Huanyi Zheng , Muzhi Zhu , Zhiyue Zhao , Hao Chen , Tong He , Chunhua Shen

Fine-tuning large pre-trained language models on downstream tasks has become the de-facto learning paradigm in NLP. However, conventional approaches fine-tune all the parameters of the pre-trained model, which becomes prohibitive as the…

Computation and Language · Computer Science 2022-02-03 Junxian He , Chunting Zhou , Xuezhe Ma , Taylor Berg-Kirkpatrick , Graham Neubig

Diffusion models have attained prominence for their ability to synthesize a probability distribution for a given dataset via a diffusion process, enabling the generation of new data points with high fidelity. However, diffusion processes…

Machine Learning · Computer Science 2024-11-25 Shervin Khalafi , Dongsheng Ding , Alejandro Ribeiro

Diffusion models have demonstrated remarkable efficacy in various generative tasks with the predictive prowess of denoising model. Currently, diffusion models employ a uniform denoising model across all timesteps. However, the inherent…

Machine Learning · Computer Science 2024-12-30 Wenhao Li , Xiu Su , Yu Han , Shan You , Tao Huang , Chang Xu

The visual models pretrained on large-scale benchmarks encode general knowledge and prove effective in building more powerful representations for downstream tasks. Most existing approaches follow the fine-tuning paradigm, either by…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Nan Zhou , Jiaxin Chen , Di Huang

Recent works on diffusion models have demonstrated a strong capability for conditioning image generation, e.g., text-guided image synthesis. Such success inspires many efforts trying to use large-scale pre-trained diffusion models for…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Zhixing Zhang , Ligong Han , Arnab Ghosh , Dimitris Metaxas , Jian Ren

Efficient finetuning of pretrained language transformers is becoming increasingly prevalent for solving natural language processing tasks. While effective, it can still require a large number of tunable parameters. This can be a drawback…

Computation and Language · Computer Science 2023-05-31 Umang Gupta , Aram Galstyan , Greg Ver Steeg

With the growing interest in foundation models for brain signals, graph-based pretraining has emerged as a promising paradigm for learning transferable representations from connectome data. However, existing contrastive and masked…

Machine Learning · Computer Science 2026-03-10 Xinxu Wei , Rong Zhou , Lifang He , Yu Zhang

We propose Diffusion-Sharpening, a fine-tuning approach that enhances downstream alignment by optimizing sampling trajectories. Existing RL-based fine-tuning methods focus on single training timesteps and neglect trajectory-level alignment,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Ye Tian , Ling Yang , Xinchen Zhang , Yunhai Tong , Mengdi Wang , Bin Cui

Deep generative models have garnered significant attention in low-level vision tasks due to their generative capabilities. Among them, diffusion model-based solutions, characterized by a forward diffusion process and a reverse denoising…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Chunming He , Yuqi Shen , Chengyu Fang , Fengyang Xiao , Longxiang Tang , Yulun Zhang , Wangmeng Zuo , Zhenhua Guo , Xiu Li

While task-specific finetuning of pretrained networks has led to significant empirical advances in NLP, the large size of networks makes finetuning difficult to deploy in multi-task, memory-constrained settings. We propose diff pruning as a…

Computation and Language · Computer Science 2021-06-10 Demi Guo , Alexander M. Rush , Yoon Kim

Reinforcement learning has emerged as a powerful tool for improving diffusion-based text-to-image models, but existing methods are largely limited to single-task optimization. Extending RL to multiple tasks is challenging: joint…

Machine Learning · Computer Science 2026-05-15 Quanhao Li , Junqiu Yu , Kaixun Jiang , Yujie Wei , Zhen Xing , Pandeng Li , Ruihang Chu , Shiwei Zhang , Yu Liu , Zuxuan Wu

Foundation models leverage large-scale pretraining to capture extensive knowledge, demonstrating generalization in a wide range of language tasks. By comparison, vision foundation models (VFMs) often exhibit uneven improvements across…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shiqi Huang , Yipei Wang , Natasha Thorley , Alexander Ng , Shaheer Saeed , Mark Emberton , Shonit Punwani , Veeru Kasivisvanathan , Dean Barratt , Daniel Alexander , Yipeng Hu

While diffusion model fine-tuning offers a powerful approach for customizing pre-trained models to generate specific objects, it frequently suffers from overfitting when training samples are limited, compromising both generalization…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Vera Soboleva , Aibek Alanov , Andrey Kuznetsov , Konstantin Sobolev

Many real-world applications require making multiple predictions from the same text. Fine-tuning a large pre-trained language model for each downstream task causes computational burdens in the inference time due to several times of forward…

Computation and Language · Computer Science 2023-10-17 Kuan-Hao Huang , Liang Tan , Rui Hou , Sinong Wang , Amjad Almahairi , Ruty Rinott

Text-to-Image diffusion models have made tremendous progress over the past two years, enabling the generation of highly realistic images based on open-domain text descriptions. However, despite their success, text descriptions often…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Shihao Zhao , Dongdong Chen , Yen-Chun Chen , Jianmin Bao , Shaozhe Hao , Lu Yuan , Kwan-Yee K. Wong