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This paper demonstrates that language models are strong structure-based protein designers. We present LM-Design, a generic approach to reprogramming sequence-based protein language models (pLMs), that have learned massive sequential…

Machine Learning · Computer Science 2023-02-10 Zaixiang Zheng , Yifan Deng , Dongyu Xue , Yi Zhou , Fei YE , Quanquan Gu

This survey organizes the intricate literature on the design and optimization of emerging structures around post-trained LMs. We refer to this overarching structure as scaffolded LMs and focus on LMs that are integrated into multi-step…

Computation and Language · Computer Science 2025-11-05 Matthieu Lin , Jenny Sheng , Andrew Zhao , Shenzhi Wang , Yang Yue , Victor Shea Jay Huang , Huan Liu , Jun Liu , Gao Huang , Yong-Jin Liu

Model editing aims to correct outdated or erroneous knowledge in large models without costly retraining. Recent research discovered that the mid-layer representation of the subject's final token in a prompt has a strong influence on factual…

Computer Vision and Pattern Recognition · Computer Science 2025-01-24 Qizhou Chen , Taolin Zhang , Chengyu Wang , Xiaofeng He , Dakan Wang , Tingting Liu

Masked diffusion language models enable parallel token generation and offer improved decoding efficiency over autoregressive models. However, their performance degrades significantly when generating multiple tokens simultaneously, due to a…

Computation and Language · Computer Science 2026-05-12 Houxing Ren , Mingjie Zhan , Zimu Lu , Ke Wang , Yunqiao Yang , Haotian Hou , Junting Pan , Hongsheng Li

Understanding the internal mechanisms by which multi-modal large language models (LLMs) interpret different modalities and integrate cross-modal representations is becoming increasingly critical for continuous improvements in both academia…

Computation and Language · Computer Science 2024-06-12 Haowen Pan , Yixin Cao , Xiaozhi Wang , Xun Yang , Meng Wang

Simplified Molecular Input Line Entry System (SMILES) is a single line text representation of a unique molecule. One molecule can however have multiple SMILES strings, which is a reason that canonical SMILES have been defined, which ensures…

Machine Learning · Computer Science 2017-05-18 Esben Jannik Bjerrum

The number of Language Models (LMs) dedicated to processing scientific text is on the rise. Keeping pace with the rapid growth of scientific LMs (SciLMs) has become a daunting task for researchers. To date, no comprehensive surveys on…

Computation and Language · Computer Science 2024-02-01 Xanh Ho , Anh Khoa Duong Nguyen , An Tuan Dao , Junfeng Jiang , Yuki Chida , Kaito Sugimoto , Huy Quoc To , Florian Boudin , Akiko Aizawa

Pre-training has proven effective for learning transferable features in sign language understanding (SLU) tasks. Recently, skeleton-based methods have gained increasing attention because they can robustly handle variations in subjects and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Muxin Pu , Mei Kuan Lim , Chun Yong Chong , Chen Change Loy

Recent advancements in image editing have utilized large-scale multimodal models to enable intuitive, natural instruction-driven interactions. However, conventional methods still face significant challenges, particularly in spatial…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Qianqian Sun , Jixiang Luo , Dell Zhang , Xuelong Li

Existing semantic segmentation approaches are often limited by costly pixel-wise annotations and predefined classes. In this work, we present CLIP-S$^4$ that leverages self-supervised pixel representation learning and vision-language models…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Wenbin He , Suphanut Jamonnak , Liang Gou , Liu Ren

While Unified Vision-Language Models promise to synergistically combine the high-level semantic understanding of vision-language models with the generative fidelity of diffusion models, current editing methodologies remain fundamentally…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Chengyu Bai , Jintao Chen , Xiang Bai , Yilong Chen , Qi She , Ming Lu , Shanghang Zhang

Large language models (LLMs) inevitably encode outdated or incorrect knowledge. Updating, deleting, and forgetting such knowledge is important for alignment, safety, and other issues. To address this issue, model editing has emerged as a…

Artificial Intelligence · Computer Science 2025-10-02 Wei Liu , Haomei Xu , Bingqing Liu , Zhiying Deng , Haozhao Wang , Jun Wang , Ruixuan Li , Yee Whye Teh , Wee Sun Lee

Pre-trained Language Model (PLM) has become a representative foundation model in the natural language processing field. Most PLMs are trained with linguistic-agnostic pre-training tasks on the surface form of the text, such as the masked…

Computation and Language · Computer Science 2022-11-11 Yiming Cui , Wanxiang Che , Shijin Wang , Ting Liu

Neurological disorders that affect speech production, such as Alzheimer's Disease (AD), significantly impact the lives of both patients and caregivers, whether through social, psycho-emotional effects or other aspects not yet fully…

Scientific language models drive research innovation but require extensive fine-tuning on large datasets. This work enhances such models by improving their inference and evaluation capabilities with minimal or no additional training.…

Computation and Language · Computer Science 2025-05-27 Dimitris Gkoumas , Maria Liakata

Lexical Simplification (LS) aims to simplify text at the lexical level. Existing methods rely heavily on annotated data, making it challenging to apply in low-resource scenarios. In this paper, we propose a novel LS method without parallel…

Computation and Language · Computer Science 2024-03-25 Keren Tan , Kangyang Luo , Yunshi Lan , Zheng Yuan , Jinlong Shu

Morphable models are essential for the statistical modeling of 3D faces. Previous works on morphable models mostly focus on large-scale facial geometry but ignore facial details. This paper augments morphable models in representing facial…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Jingwang Ling , Zhibo Wang , Ming Lu , Quan Wang , Chen Qian , Feng Xu

Most language modeling methods rely on large-scale data to statistically learn the sequential patterns of words. In this paper, we argue that words are atomic language units but not necessarily atomic semantic units. Inspired by HowNet, we…

Computation and Language · Computer Science 2018-10-31 Yihong Gu , Jun Yan , Hao Zhu , Zhiyuan Liu , Ruobing Xie , Maosong Sun , Fen Lin , Leyu Lin

Existing instruction-based image editing models perform well with simple, single-step instructions but degrade in realistic scenarios that involve multiple, lengthy, and interdependent directives. A main cause is the scarcity of training…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Zhaoyuan Qiu , Ken Chen , Xiangwei Wang , Yu Xia , Sachith Seneviratne , Saman Halgamuge

Text images are unique in their dual nature, encompassing both visual and linguistic information. The visual component encompasses structural and appearance-based features, while the linguistic dimension incorporates contextual and semantic…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Yifei Zhang , Chang Liu , Jin Wei , Xiaomeng Yang , Yu Zhou , Can Ma , Xiangyang Ji