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In this paper, we consider to what degree the structure of a linear system is determined by the system's input/output behavior. The structure of a linear system is a directed graph where the vertices represent the variables in the system…

Optimization and Control · Mathematics 2011-09-19 Remco Bras

Stochasticity plays a key role in many biological systems, necessitating the calibration of stochastic mathematical models to interpret associated data. For model parameters to be estimated reliably, it is typically the case that they must…

The use of patterns in predictive models is a topic that has received a lot of attention in recent years. Pattern mining can help to obtain models for structured domains, such as graphs and sequences, and has been proposed as a means to…

Artificial Intelligence · Computer Science 2011-11-29 Björn Bringmann , Siegfried Nijssen , Albrecht Zimmermann

The identifiability analysis of linear Ordinary Differential Equation (ODE) systems is a necessary prerequisite for making reliable causal inferences about these systems. While identifiability has been well studied in scenarios where the…

Machine Learning · Statistics 2024-10-31 Yuanyuan Wang , Biwei Huang , Wei Huang , Xi Geng , Mingming Gong

The paper introduces a generalization for known probabilistic models such as log-linear and graphical models, called here multiplicative models. These models, that express probabilities via product of parameters are shown to capture…

Artificial Intelligence · Computer Science 2012-06-18 Ydo Wexler , Christopher Meek

Graphical models can represent a multivariate distribution in a convenient and accessible form as a graph. Causal models can be viewed as a special class of graphical models that not only represent the distribution of the observed system…

Methodology · Statistics 2017-06-29 Christina Heinze-Deml , Marloes H. Maathuis , Nicolai Meinshausen

Causal representation learning aims to unveil latent high-level causal representations from observed low-level data. One of its primary tasks is to provide reliable assurance of identifying these latent causal models, known as…

Machine Learning · Computer Science 2024-12-02 Yuhang Liu , Zhen Zhang , Dong Gong , Mingming Gong , Biwei Huang , Anton van den Hengel , Kun Zhang , Javen Qinfeng Shi

Ordinary differential equations (ODEs) are widely used to model dynamical behavior of systems. It is important to perform identifiability analysis prior to estimating unknown parameters in ODEs (a.k.a. inverse problem), because if a system…

Optimization and Control · Mathematics 2021-03-11 Xing Qiu , Tao Xu , Babak Soltanalizadeh , Hulin Wu

Cross-sectional observations from a dynamical system can be modeled via steady-state distributions of Markov processes. The major challenge is then to determine whether the process parameters can be identified and estimated from the…

Statistics Theory · Mathematics 2026-03-19 Cecilie Olesen Recke , Niels Richard Hansen

The problem of identifiability of finite mixtures of finite product measures is studied. A mixture model with $K$ mixture components and $L$ observed variables is considered, where each variable takes its value in a finite set with…

Statistics Theory · Mathematics 2018-07-17 Behrooz Tahmasebi , Seyed Abolfazl Motahari , Mohammad Ali Maddah-Ali

A Profile Mixture Model is a model of protein evolution, describing sequence data in which sites are assumed to follow many related substitution processes on a single evolutionary tree. The processes depend in part on different amino acid…

Populations and Evolution · Quantitative Biology 2020-07-07 Samaneh Yourdkhani , Elizabeth S. Allman , John A. Rhodes

Computational and mathematical models rely heavily on estimated parameter values for model development. Identifiability analysis determines how well the parameters of a model can be estimated from experimental data. Identifiability analysis…

Quantitative Methods · Quantitative Biology 2021-02-12 Marissa Renardy , Denise Kirschner , Marisa Eisenberg

An important task in data analysis is the discovery of causal relationships between observed variables. For continuous-valued data, linear acyclic causal models are commonly used to model the data-generating process, and the inference of…

Causal additive models provide a tractable yet expressive framework for causal discovery in the presence of hidden variables. When unobserved backdoor or causal paths exist between two variables, their causal relationship is often…

Machine Learning · Computer Science 2026-05-25 Thong Pham , Takashi Nicholas Maeda , Shohei Shimizu

The parameter identifiability problem for a dynamical system is to determine whether the parameters of the system can be found from data for the outputs of the system. Verifying whether the parameters are identifiable is a necessary first…

Systems and Control · Electrical Eng. & Systems 2025-06-11 Alexey Ovchinnikov , Anand Pillay , Gleb Pogudin , Thomas Scanlon

This paper considers a challenging problem of identifying a causal graphical model under the presence of latent variables. While various identifiability conditions have been proposed in the literature, they often require multiple pure…

Machine Learning · Statistics 2026-02-03 Seunghyun Lee , Yuqi Gu

Independent cascade (IC) model is a widely used influence propagation model for social networks. In this paper, we incorporate the concept and techniques from causal inference to study the identifiability of parameters from observational…

Social and Information Networks · Computer Science 2021-12-10 Shi Feng , Wei Chen

The exact parameter values of mathematical models are often uncertain or even unknown. Nevertheless, we may have access to crude information about the parameters, e.g., that some of them are nonzero. Such information can be captured by…

Optimization and Control · Mathematics 2020-11-25 B. M. Shali , H. J. van Waarde , M. K. Camlibel , H. L. Trentelman

Mathematical models are invaluable for understanding and predicting how biological systems behave, although their construction requires specifying mechanisms and relationships that are often not perfectly known. In the presence of multiple…

By taking into account the nonlinear effect of the cause, the inner noise effect, and the measurement distortion effect in the observed variables, the post-nonlinear (PNL) causal model has demonstrated its excellent performance in…

Machine Learning · Statistics 2012-05-14 Kun Zhang , Aapo Hyvarinen
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