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Generalizability is a concern when applying a deep learning (DL) model trained on one dataset to other datasets. Training a universal model that works anywhere, anytime, for anybody is unrealistic. In this work, we demonstrate the…

Medical Physics · Physics 2020-04-20 Xiao Liang , Dan Nguyen , Steve Jiang

Computed Tomography (CT) reconstruction is a fundamental component to a wide variety of applications ranging from security, to healthcare. The classical techniques require measuring projections, called sinograms, from a full 180$^\circ$…

Computer Vision and Pattern Recognition · Computer Science 2018-07-12 Rushil Anirudh , Hyojin Kim , Jayaraman J. Thiagarajan , K. Aditya Mohan , Kyle Champley , Timo Bremer

Computed Tomography (CT) is an imaging technique where information about an object are collected at different angles (called projections or scans). Then the cross-sectional image showing the internal structure of the slice is produced by…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Zhengchun Liu , Rajkumar Kettimuthu , Ian Foster

The inversion of linear systems is a fundamental step in many inverse problems. Computational challenges exist when trying to invert large linear systems, where limited computing resources mean that only part of the system can be kept in…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-09-05 Yushan Gao , Thomas Blumensath

In image-guided radiotherapy (IGRT), four-dimensional cone-beam computed tomography (4D-CBCT) is critical for assessing tumor motion during a patients breathing cycle prior to beam delivery. However, generating 4D-CBCT images with…

Medical Physics · Physics 2025-01-09 Yabo Fu , Hao Zhang , Weixing Cai , Huiqiao Xie , Licheng Kuo , Laura Cervino , Jean Moran , Xiang Li , Tianfang Li

Recent advances in deep learning for 3D point clouds have shown great promises in scene understanding tasks thanks to the introduction of convolution operators to consume 3D point clouds directly in a neural network. Point cloud data,…

Computer Vision and Pattern Recognition · Computer Science 2020-08-10 Zhiyuan Zhang , Binh-Son Hua , Wei Chen , Yibin Tian , Sai-Kit Yeung

This work is concerned with fan- and cone-beam computed tomography with circular source trajectory, where the reconstruction inverse problem requires an accurate knowledge of source, detector and rotational axis relative positions and…

Numerical Analysis · Mathematics 2024-05-09 Patricio Guerrero , Simon Bellens , Ricardo Santander , Wim Dewulf

Simulation of x-ray projection images plays an important role in cone beam CT (CBCT) related research projects. A projection image contains primary signal, scatter signal, and noise. It is computationally demanding to perform accurate and…

Medical Physics · Physics 2015-06-04 Xun Jia , Hao Yan , Laura Cervino , Michael Folkerts , Steve B. Jiang

We present a new method for image reconstruction which replaces the projector in a projected gradient descent (PGD) with a convolutional neural network (CNN). CNNs trained as high-dimensional (image-to-image) regressors have recently been…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Harshit Gupta , Kyong Hwan Jin , Ha Q. Nguyen , Michael T. McCann , Michael Unser

Bayesian inference with deep generative prior has received considerable interest for solving imaging inverse problems in many scientific and engineering fields. The selection of the prior distribution is learned from, and therefore an…

Machine Learning · Statistics 2023-10-30 Jiayu Qian , Yuanyuan Liu , Jingya Yang , Qingping Zhou

Cone-beam CT (CBCT) has been widely used in image guided radiation therapy (IGRT) to acquire updated volumetric anatomical information before treatment fractions for accurate patient alignment purpose. However, the excessive x-ray imaging…

Medical Physics · Physics 2010-04-13 Xun Jia , Yifei Lou , John Lewis , Ruijiang Li , Xuejun Gu , Chunhua Men , William Y. Song , Steve B. Jiang

English: This paper concerns the image reconstruction from a few projections in Computed Tomography (CT). The main objective of this paper is to show that the problem is so ill posed that no classical method, such as analytical methods…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Ali Mohammad-Djafari

Belief Propagation (BP) is one of the most popular methods for inference in probabilistic graphical models. BP is guaranteed to return the correct answer for tree structures, but can be incorrect or non-convergent for loopy graphical…

Artificial Intelligence · Computer Science 2012-06-22 Siamak Ravanbakhsh , Chun-Nam Yu , Russell Greiner

Cone-Beam Computed Tomography (CBCT) is an indispensable technique in medical imaging, yet the associated radiation exposure raises concerns in clinical practice. To mitigate these risks, sparse-view reconstruction has emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Yiqun Lin , Hualiang Wang , Jixiang Chen , Xiaomeng Li

Cone-beam CT (CBCT) employs a flat-panel detector to achieve three-dimensional imaging with high spatial resolution. However, CBCT is susceptible to scatter during data acquisition, which introduces CT value bias and reduced tissue contrast…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Xu Jiang , Huiying Pan , Ligen Shi , Jianing Sun , Wenfeng Xu , Xing Zhao

In the recent years, there has been a significant improvement in the quality of samples produced by (deep) generative models such as variational auto-encoders and generative adversarial networks. However, the representation capabilities of…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Shady Abu Hussein , Tom Tirer , Raja Giryes

Computed Tomography (CT) reconstruction of objects with cylindrical symmetry can be performed with a single projection. When the measured rays are parallel, and the axis of symmetry is perpendicular to the optical axis, the data can be…

Medical Physics · Physics 2024-10-15 Kyle M. Champley , Ibrahim Oksuz , Matthew G. Bisbee , Joseph W. Tringe , Brian Maddox

Sparse-view Computed Tomography (CT) is an emerging protocol designed to reduce X-ray dose radiation in medical imaging. Traditional Filtered Back Projection algorithm reconstructions suffer from severe artifacts due to sparse data. In…

Numerical Analysis · Mathematics 2024-12-03 Elena Loli Piccolomini , Davide Evangelista , Elena Morotti

Coarse-graining (CG) of molecular simulations simplifies the particle representation by grouping selected atoms into pseudo-beads and drastically accelerates simulation. However, such CG procedure induces information losses, which makes…

Machine Learning · Computer Science 2022-06-20 Wujie Wang , Minkai Xu , Chen Cai , Benjamin Kurt Miller , Tess Smidt , Yusu Wang , Jian Tang , Rafael Gómez-Bombarelli

Doing quantitative computed tomography (CT) using Bremsstrahlung sources requires an estimate of the spectrum emitted by the X-ray source. One method of beam hardening correction (BHC), as described by Lifton[1], first uses transmission…

Medical Physics · Physics 2025-08-13 Nikhil Deshmukh