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Histopathology image embedding is an active research area in computer vision. Most of the embedding models exclusively concentrate on a specific magnification level. However, a useful task in histopathology embedding is to train an…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Milad Sikaroudi , Benyamin Ghojogh , Fakhri Karray , Mark Crowley , H. R. Tizhoosh

Self-supervised instance discrimination is an effective contrastive pretext task to learn feature representations and address limited medical image annotations. The idea is to make features of transformed versions of the same images similar…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Yejia Zhang , Xinrong Hu , Nishchal Sapkota , Yiyu Shi , Danny Z. Chen

An important part of Digital Pathology is the analysis of multiple digitised whole slide images from differently stained tissue sections. It is common practice to mount consecutive sections containing corresponding microscopic structures on…

Computer Vision and Pattern Recognition · Computer Science 2018-11-06 Thomas Lampert , Odyssée Merveille , Jessica Schmitz , Germain Forestier , Friedrich Feuerhake , Cédric Wemmert

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in real-world applications: 1) only limited labels are available for model training, due to…

Computer Vision and Pattern Recognition · Computer Science 2020-08-26 Yifan Zhang , Ying Wei , Qingyao Wu , Peilin Zhao , Shuaicheng Niu , Junzhou Huang , Mingkui Tan

Supervised learning algorithms trained on medical images will often fail to generalize across changes in acquisition parameters. Recent work in domain adaptation addresses this challenge and successfully leverages labeled data in a source…

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

Unsupervised domain adaptation aiming to learn a specific task for one domain using another domain data has emerged to address the labeling issue in supervised learning, especially because it is difficult to obtain massive amounts of…

Machine Learning · Computer Science 2019-03-13 Jaeyoon Yoo , Changhwa Park , Yongjun Hong , Sungroh Yoon

Whole Slide Images (WSIs) or histopathology images are used in digital pathology. WSIs pose great challenges to deep learning models for clinical diagnosis, owing to their size and lack of pixel-level annotations. With the recent…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Soham Rohit Chitnis , Sidong Liu , Tirtharaj Dash , Tanmay Tulsidas Verlekar , Antonio Di Ieva , Shlomo Berkovsky , Lovekesh Vig , Ashwin Srinivasan

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Supervised learning with large scale labeled datasets and deep layered models has made a paradigm shift in diverse areas in learning and recognition. However, this approach still suffers generalization issues under the presence of a domain…

Machine Learning · Statistics 2016-03-28 Ozan Sener , Hyun Oh Song , Ashutosh Saxena , Silvio Savarese

In computational pathology, deep learning (DL) models for tasks such as segmentation or tissue classification are known to suffer from domain shifts due to different staining techniques. Stain adaptation aims to reduce the generalization…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Daniel Reisenbüchler , Lucas Luttner , Nadine S. Schaadt , Friedrich Feuerhake , Dorit Merhof

The need for training data can impede the adoption of novel imaging modalities for learning-based medical image analysis. Domain adaptation methods partially mitigate this problem by translating training data from a related source domain to…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Eleni Chiou , Francesco Giganti , Shonit Punwani , Iasonas Kokkinos , Eleftheria Panagiotaki

Despite their success in many computer vision tasks, convolutional networks tend to require large amounts of labeled data to achieve generalization. Furthermore, the performance is not guaranteed on a sample from an unseen domain at test…

Computer Vision and Pattern Recognition · Computer Science 2019-09-09 Ozan Ciga , Jianan Chen , Anne Martel

In digital pathology, different staining procedures and scanners cause substantial color variations in whole-slide images (WSIs), especially across different laboratories. These color shifts result in a poor generalization of deep…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Sophia J. Wagner , Nadieh Khalili , Raghav Sharma , Melanie Boxberg , Carsten Marr , Walter de Back , Tingying Peng

Existing unsupervised domain adaptation methods based on adversarial learning have achieved good performance in several medical imaging tasks. However, these methods focus only on global distribution adaptation and ignore distribution…

Computer Vision and Pattern Recognition · Computer Science 2022-07-11 Wei Feng , Lin Wang , Lie Ju , Xin Zhao , Xin Wang , Xiaoyu Shi , Zongyuan Ge

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Adapting machine learning models to medical time series across different domains remains a challenge due to complex temporal dependencies and dynamic distribution shifts. Current approaches often focus on isolated feature representations,…

Machine Learning · Computer Science 2025-09-23 YongKyung Oh , Alex Bui

For histopathological tumor assessment, the count of mitotic figures per area is an important part of prognostication. Algorithmic approaches - such as for mitotic figure identification - have significantly improved in recent times,…

Computer Vision and Pattern Recognition · Computer Science 2020-02-20 Marc Aubreville , Christof A. Bertram , Samir Jabari , Christian Marzahl , Robert Klopfleisch , Andreas Maier

Contrastive learning, which aims to capture general representation from unlabeled images to initialize the medical analysis models, has been proven effective in alleviating the high demand for expensive annotations. Current methods mainly…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Huai Chen , Renzhen Wang , Xiuying Wang , Jieyu Li , Qu Fang , Hui Li , Jianhao Bai , Qing Peng , Deyu Meng , Lisheng Wang

The aim of this paper is to give an overview of domain adaptation and transfer learning with a specific view on visual applications. After a general motivation, we first position domain adaptation in the larger transfer learning problem.…

Computer Vision and Pattern Recognition · Computer Science 2017-03-31 Gabriela Csurka
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