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Related papers: Boundary-Guided Learning for Gene Expression Predi…

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Beamforming (BF) is essential for enhancing system capacity in fifth generation (5G) and beyond wireless networks, yet exhaustive beam training in ultra-massive multiple-input multiple-output (MIMO) systems incurs substantial overhead. To…

Signal Processing · Electrical Eng. & Systems 2026-02-11 Yanliang Jin , Yunfan Li , Jiang Jun , Yuan Gao , Shengli Liu , Jianbo Du , Zhaohui Yang , Shugong Xu

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min

The advancement of Spatial Transcriptomics (ST) has facilitated the spatially-aware profiling of gene expressions based on histopathology images. Although ST data offers valuable insights into the micro-environment of tumors, its…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Hongyi Wang , Xiuju Du , Jing Liu , Shuyi Ouyang , Yen-Wei Chen , Lanfen Lin

Recognizing traversable terrain from 3D point cloud data is critical, as it directly impacts the performance of autonomous navigation in off-road environments. However, existing segmentation algorithms often struggle with challenges related…

Despite impressive performance as evaluated on i.i.d. holdout data, deep neural networks depend heavily on superficial statistics of the training data and are liable to break under distribution shift. For example, subtle changes to the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-18 Haohan Wang , Zexue He , Zachary C. Lipton , Eric P. Xing

Gene expression is a cellular process that plays a fundamental role in human phenotypical variations and diseases. Despite advances of deep learning models for gene expression prediction, recent benchmarks have revealed their inability to…

Cell Behavior · Quantitative Biology 2024-10-04 Edouardo Honig , Huixin Zhan , Ying Nian Wu , Zijun Frank Zhang

Spatiotemporal gene expression data of the human brain offer insights on the spa- tial and temporal patterns of gene regulation during brain development. Most existing methods for analyzing these data consider spatial and temporal profiles…

Methodology · Statistics 2017-02-27 Tianqi Liu , Ming Yuan , Hongyu Zhao

Histology imaging is an important tool in medical diagnosis and research, enabling the examination of tissue structure and composition at the microscopic level. Understanding the underlying molecular mechanisms of tissue architecture is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Ronald Xie , Kuan Pang , Sai W. Chung , Catia T. Perciani , Sonya A. MacParland , Bo Wang , Gary D. Bader

Molecular and morphological characters, as important parts of biological taxonomy, are contradictory but need to be integrated. Organism's image recognition and bioinformatics are emerging and hot problems nowadays but with a gap between…

Computer Vision and Pattern Recognition · Computer Science 2022-06-29 Jiewen Xiao , Wenbin Liao , Ming Zhang , Jing Wang , Jianxin Wang , Yihua Yang

Identifying objective neuroimaging biomarkers to forecast Alzheimer's disease (AD) progression is crucial for timely intervention. However, this task remains challenging due to the complex dysfunctions in the spatio-temporal characteristics…

Human and animal tissues consist of heterogeneous cell types that organize and interact in highly structured manners. Bulk and single-cell sequencing technologies remove cells from their original microenvironments, resulting in a loss of…

Quantitative Methods · Quantitative Biology 2022-02-08 Boxiang Liu , Yanjun Li , Liang Zhang

Land use and land cover mapping from Earth Observation (EO) data is a critical tool for sustainable land and resource management. While advanced machine learning and deep learning algorithms excel at analyzing EO imagery data, they often…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Babak Ghassemi , Cassio Fraga-Dantas , Raffaele Gaetano , Dino Ienco , Omid Ghorbanzadeh , Emma Izquierdo-Verdiguier , Francesco Vuolo

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Spatial transcriptomics enables spatial gene expression profiling, motivating computational models that capture spatially conditioned regulatory relationships. We introduce SAGE-FM, a lightweight spatial transcriptomics foundation model…

Machine Learning · Computer Science 2026-01-23 Xianghao Zhan , Jingyu Xu , Yuanning Zheng , Zinaida Good , Olivier Gevaert

The integration of spatial multi-omics data from single tissues is crucial for advancing biological research. However, a significant data imbalance impedes progress: while spatial transcriptomics data is relatively abundant, spatial…

Artificial Intelligence · Computer Science 2026-02-06 Zhaorui Jiang , Yingfang Yuan , Lei Hu , Wei Pang

In this paper, we propose a Boundary-aware Graph Reasoning (BGR) module to learn long-range contextual features for semantic segmentation. Rather than directly construct the graph based on the backbone features, our BGR module explores a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Haoteng Tang , Haozhe Jia , Weidong Cai , Heng Huang , Yong Xia , Liang Zhan

Segmentation is an essential operation of image processing. The convolution operation suffers from a limited receptive field, while global modelling is fundamental to segmentation tasks. In this paper, we apply graph convolution into the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Yanda Meng , Hongrun Zhang , Dongxu Gao , Yitian Zhao , Xiaoyun Yang , Xuesheng Qian , Xiaowei Huang , Yalin Zheng

Scene Graph Generation (SGG) aims to identify entities and predict the relationship triplets \textit{\textless subject, predicate, object\textgreater } in visual scenes. Given the prevalence of large visual variations of subject-object…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Jiankai Li , Yunhong Wang , Xiefan Guo , Ruijie Yang , Weixin Li

Biological oscillations are periodic changes in various signaling processes crucial for the proper functioning of living organisms. These oscillations are modeled by ordinary differential equations, with coefficient variations leading to…

Machine Learning · Computer Science 2024-12-04 Heng Rao , Yu Gu , Jason Zipeng Zhang , Ge Yu , Yang Cao , Minghan Chen

Transformer-based models have achieved remarkable success in natural language and vision tasks, but their application to gene expression analysis remains limited due to data sparsity, high dimensionality, and missing values. We present…

Machine Learning · Computer Science 2025-04-15 Shuai Jiang , Saeed Hassanpour