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Accurate decoding of neural spike trains and relating them to motor output is a challenging task due to the inherent sparsity and length in neural spikes and the complexity of brain circuits. This master project investigates experimental…

Neurons and Cognition · Quantitative Biology 2025-02-13 Fei Gao

The advent of large scale neural computational platforms has highlighted the lack of algorithms for synthesis of neural structures to perform predefined cognitive tasks. The Neural Engineering Framework offers one such synthesis, but it is…

Neural and Evolutionary Computing · Computer Science 2013-04-29 J. Tapson , G. Cohen , S. Afshar , K. Stiefel , Y. Buskila , R. Wang , T. J. Hamilton , A. van Schaik

Coaxing out desired behavior from pretrained models, while avoiding undesirable ones, has redefined NLP and is reshaping how we interact with computers. What was once a scientific engineering discipline-in which building blocks are stacked…

Machine Learning · Computer Science 2023-08-02 Ari Holtzman , Peter West , Luke Zettlemoyer

There is extensive evidence that biological neural networks encode information in the precise timing of the spikes generated and transmitted by neurons, which offers several advantages over rate-based codes. Here we adopt a vector space…

Neurons and Cognition · Quantitative Biology 2019-07-16 Dorian Florescu , Daniel Coca

Methods and insights from statistical physics are finding an increasing variety of applications where one seeks to understand the emergent properties of a complex interacting system. One such area concerns the dynamics of language at a…

Physics and Society · Physics 2015-11-13 Richard A. Blythe

Diverse scientific and engineering research areas deal with discrete, time-stamped changes in large systems of interacting delay differential equations. Simulating such complex systems at scale on high-performance computing clusters demands…

Understanding how the dynamics of neural networks is shaped by the computations they perform is a fundamental question in neuroscience. Recently, the framework of efficient coding proposed a theory of how spiking neural networks can compute…

Neurons and Cognition · Quantitative Biology 2022-10-25 Veronika Koren , Stefano Panzeri

Information encoding in the nervous system is supported through the precise spike-timings of neurons; however, an understanding of the underlying processes by which such representations are formed in the first place remains unclear. Here we…

Neural and Evolutionary Computing · Computer Science 2015-12-01 Brian Gardner , Ioana Sporea , André Grüning

Prompted models have demonstrated impressive few-shot learning abilities. Repeated interactions at test-time with a single model, or the composition of multiple models together, further expands capabilities. These compositions are…

The problem of neural coding is to understand how sequences of action potentials (spikes) are related to sensory stimuli, motor outputs, or (ultimately) thoughts and intentions. One clear question is whether the same coding rules are used…

Individual neurons often produce highly variable responses over nominally identical trials, reflecting a mixture of intrinsic "noise" and systematic changes in the animal's cognitive and behavioral state. Disentangling these sources of…

Neurons and Cognition · Quantitative Biology 2021-11-08 Alex H. Williams , Scott W. Linderman

We propose a construction for joint feature learning and clustering of multichannel extracellular electrophysiological data across multiple recording periods for action potential detection and discrimination ("spike sorting"). Our…

Neurophysiologists are nowadays able to record from a large number of extracellular electrodes and to extract, from the raw data, the sequences of action potentials or spikes generated by many neurons. Unfortunately these ''many neurons''…

Applications · Statistics 2026-04-22 Pierre Charitat , Ségolen Geffray , Christophe Pouzat

A vast majority of computation in the brain is performed by spiking neural networks. Despite the ubiquity of such spiking, we currently lack an understanding of how biological spiking neural circuits learn and compute in-vivo, as well as…

Neurons and Cognition · Quantitative Biology 2018-05-31 Friedemann Zenke , Surya Ganguli

A fundamental challenge in the cognitive sciences is discovering the dynamics that govern behaviour. Take the example of spoken language, which is characterised by a highly variable and complex set of physical movements that map onto the…

Computation and Language · Computer Science 2025-05-06 Sam Kirkham

Human brain neuron activities are incredibly significant nowadays. Neuronal behavior is assessed by analyzing signal data such as electroencephalography (EEG), which can offer scientists valuable information about diseases and…

Modern well-performing approaches to neural decoding are based on machine learning models such as decision tree ensembles and deep neural networks. The wide range of algorithms that can be utilized to learn from neural spike trains, which…

Neurons and Cognition · Quantitative Biology 2023-01-30 Ivan Lazarevich , Ilya Prokin , Boris Gutkin , Victor Kazantsev

Recent experimental advances in neuroscience have opened new vistas into the immense complexity of neuronal networks. This proliferation of data challenges us on two parallel fronts. First, how can we form adequate theoretical frameworks…

Neurons and Cognition · Quantitative Biology 2015-06-12 Madhu Advani , Subhaneil Lahiri , Surya Ganguli

Spiking neural networks are the basis of versatile and power-efficient information processing in the brain. Although we currently lack a detailed understanding of how these networks compute, recently developed optimization techniques allow…

Neural and Evolutionary Computing · Computer Science 2021-01-01 Benjamin Cramer , Yannik Stradmann , Johannes Schemmel , Friedemann Zenke

A key question in neuroscience is at which level functional meaning emerges from biophysical phenomena. In most vertebrate systems, precise functions are assigned at the level of neural populations, while single-neurons are deemed…

Neurons and Cognition · Quantitative Biology 2017-03-17 Wieland Brendel , Ralph Bourdoukan , Pietro Vertechi , Christian K. Machens , Sophie Denéve