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Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…

Machine Learning · Computer Science 2024-05-08 Bing Hu , Ashish Saragadam , Anita Layton , Helen Chen

This paper introduces an approach to endow generative diffusion processes the ability to satisfy and certify compliance with constraints and physical principles. The proposed method recast the traditional sampling process of generative…

Machine Learning · Computer Science 2024-11-05 Jacob K Christopher , Stephen Baek , Ferdinando Fioretto

Currently, high-fidelity text-to-image models are developed in an accelerating pace. Among them, Diffusion Models have led to a remarkable improvement in the quality of image generation, making it vary challenging to distinguish between…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Ziyue Zeng , Haoyuan Liu , Dingjie Peng , Luoxu Jing , Hiroshi Watanabe

We propose a method that augments a simulated dataset using diffusion models to improve the performance of pedestrian detection in real-world data. The high cost of collecting and annotating data in the real-world has motivated the use of…

Computer Vision and Pattern Recognition · Computer Science 2023-05-17 Andrew Farley , Mohsen Zand , Michael Greenspan

Generative diffusion models showed high success in many fields with a powerful theoretical background. They convert the data distribution to noise and remove the noise back to obtain a similar distribution. Many existing reviews focused on…

Machine Learning · Computer Science 2024-09-19 Melike Nur Yeğin , Mehmet Fatih Amasyalı

Generating synthetic ECG data has numerous applications in healthcare, from educational purposes to simulating scenarios and forecasting trends. While recent diffusion models excel at generating short ECG segments, they struggle with longer…

Signal Processing · Electrical Eng. & Systems 2025-05-27 Paul Pöhl , Viktor Schlegel , Hao Li , Anil Bharath

This paper introduces a methodology for generating synthetic annotated data to address data scarcity in semantic segmentation tasks within the precision agriculture domain. Utilizing Denoising Diffusion Probabilistic Models (DDPMs) and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-07 Andrew Heschl , Mauricio Murillo , Keyhan Najafian , Farhad Maleki

Modern studies of societal phenomena rely on the availability of large datasets capturing attributes and activities of synthetic, city-level, populations. For instance, in epidemiology, synthetic population datasets are necessary to study…

Databases · Computer Science 2016-02-26 Hao Wu , Yue Ning , Prithwish Chakraborty , Jilles Vreeken , Nikolaj Tatti , Naren Ramakrishnan

Single-cell RNA sequencing (scRNA-seq) data are important for studying the laws of life at single-cell level. However, it is still challenging to obtain enough high-quality scRNA-seq data. To mitigate the limited availability of data,…

Quantitative Methods · Quantitative Biology 2024-03-06 Erpai Luo , Minsheng Hao , Lei Wei , Xuegong Zhang

This article provides a comprehensive synthesis of the recent developments in synthetic data generation via deep generative models, focusing on tabular datasets. We specifically outline the importance of synthetic data generation in the…

Machine Learning · Computer Science 2023-08-29 Conor Hassan , Robert Salomone , Kerrie Mengersen

Over recent years, denoising diffusion generative models have come to be considered as state-of-the-art methods for synthetic data generation, especially in the case of generating images. These approaches have also proved successful in…

Machine Learning · Computer Science 2023-06-30 Stratis Limnios , Praveen Selvaraj , Mihai Cucuringu , Carsten Maple , Gesine Reinert , Andrew Elliott

Being the most cutting-edge generative methods, diffusion methods have shown great advances in wide generation tasks. Among them, graph generation attracts significant research attention for its broad application in real life. In our…

Machine Learning · Computer Science 2024-07-17 Hongyang Chen , Can Xu , Lingyu Zheng , Qiang Zhang , Xuemin Lin

Limited data availability in machine learning significantly impacts performance and generalization. Traditional augmentation methods enhance moderately sufficient datasets. GANs struggle with convergence when generating diverse samples.…

Machine Learning · Computer Science 2024-10-02 Vahid Jebraeeli , Bo Jiang , Hamid Krim , Derya Cansever

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

Machine Learning · Computer Science 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

Dataset bias is a significant challenge in machine learning, where specific attributes, such as texture or color of the images are unintentionally learned resulting in detrimental performance. To address this, previous efforts have focused…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Donggeun Ko , Sangwoo Jo , Dongjun Lee , Namjun Park , Jaekwang Kim

Large-scale generative models, such as text-to-image diffusion models, have garnered widespread attention across diverse domains due to their creative and high-fidelity image generation. Nonetheless, existing large-scale diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Younghyun Kim , Geunmin Hwang , Junyu Zhang , Eunbyung Park

Diffusion models have demonstrated remarkable synthesis quality and diversity in generating co-speech gestures. However, the computationally intensive sampling steps associated with diffusion models hinder their practicality in real-world…

Graphics · Computer Science 2025-03-24 Yongkang Cheng , Shaoli Huang , Xuelin Chen , Jifeng Ning , Mingming Gong

The scarcity of accessible, compliant, and ethically sourced data presents a considerable challenge to the adoption of artificial intelligence (AI) in sensitive fields like healthcare, finance, and biomedical research. Furthermore, access…

Machine Learning · Computer Science 2025-04-02 Kumar Kshitij Patel , Weitong Zhang , Lingxiao Wang

We introduce the concept of deceptive diffusion -- training a generative AI model to produce adversarial images. Whereas a traditional adversarial attack algorithm aims to perturb an existing image to induce a misclassificaton, the…

Machine Learning · Computer Science 2024-07-01 Lucas Beerens , Catherine F. Higham , Desmond J. Higham

Individual-level data (microdata) that characterizes a population, is essential for studying many real-world problems. However, acquiring such data is not straightforward due to cost and privacy constraints, and access is often limited to…

Machine Learning · Computer Science 2022-12-13 Angeela Acharya , Siddhartha Sikdar , Sanmay Das , Huzefa Rangwala
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