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While quantum machine learning (ML) has been proposed to be one of the most promising applications of quantum computing, how to build quantum ML models that outperform classical ML remains a major open question. Here, we demonstrate a…

Quantum Physics · Physics 2023-03-10 Elham Torabian , Roman V. Krems

Quantum Layout Synthesis (QLS) plays a crucial role in optimizing quantum circuit execution on physical quantum devices. As we enter the era where quantum computers have hundreds of qubits, we are faced with scalability issues using optimal…

Quantum Physics · Physics 2024-12-05 Wan-Hsuan Lin , Jason Cong

Given the limitations of current hardware, the theoretical gains promised by quantum computing remain unrealized across practical applications. But the gap between theory and hardware is closing, assisted by developments in quantum…

Quantum Physics · Physics 2023-10-30 Elena R. Henderson , Harsha Nagarajan , Carleton Coffrin

The Research & Development (R&D) phase of drug development is a lengthy and costly process. To revolutionize this process, we introduce our new concept QMLS to shorten the whole R&D phase to three to six months and decrease the cost to…

Biomolecules · Quantitative Biology 2024-09-06 Yifan Zhou , Yan Shing Liang , Yew Kee Wong , Haichuan Qiu , Yu Xi Wu , Bin He

Any potential application of quantum computing, once encoded as a quantum circuit, needs to be compiled in order to be executed on a quantum computer. Deciding which qubit technology, which device, which compiler, and which corresponding…

Quantum Physics · Physics 2024-06-25 Nils Quetschlich , Lukas Burgholzer , Robert Wille

We study the course allocation problem, where universities assign course schedules to students. The current state-of-the-art mechanism, Course Match, has one major shortcoming: students make significant mistakes when reporting their…

Computer Science and Game Theory · Computer Science 2025-01-24 Ermis Soumalias , Behnoosh Zamanlooy , Jakob Weissteiner , Sven Seuken

The quantum circuit mapping approach is an indispensable part of the software stack for the noisy intermediatescale quantum (NISQ) device. It has a significant impact on the reliability of computational tasks on NISQ devices. To improve the…

Quantum Physics · Physics 2021-12-02 Pengcheng Zhu , Weiping Ding , Lihua Wei , Zhijin Guan , Shiguang Feng

Simulating molecular systems on quantum processors has the potential to surpass classical methods in computational resource efficiency. The limited qubit connectivity, small processor size, and short coherence times of near-term quantum…

Quantum Physics · Physics 2025-04-08 Abhishek Sadhu , Aritra Sarkar , Akash Kundu

This paper presents a novel approach to quantum architecture search by integrating the techniques of ZX-calculus with Genetic Programming (GP) to optimize the structure of parameterized quantum circuits employed in Quantum Machine Learning…

Quantum Physics · Physics 2025-03-21 Tom Ewen , Ivica Turkalj , Patrick Holzer , Mark-Oliver Wolf

Machine Learning (ML) has been widely applied across numerous domains due to its ability to automatically identify informative patterns from data for various tasks. The availability of large-scale data and advanced computational power…

Solving real-world optimization problems with quantum computing requires choosing between a large number of options concerning formulation, encoding, algorithm and hardware. Finding good solution paths is challenging for end users and…

The qubit mapping problem (QMP) focuses on the mapping and routing of qubits in quantum circuits so that the strict connectivity constraints imposed by near-term quantum hardware are satisfied. QMP is a pivotal task for quantum circuit…

Quantum Physics · Physics 2024-09-10 Yunqi Huang , Xiangzhen Zhou , Fanxu Meng , Sanjiang Li

The performance of Variational Quantum Algorithms (VQAs) strongly depends on the choice of the parameterized quantum circuit to optimize. One of the biggest challenges in VQAs is designing quantum circuits tailored to the particular…

Quantum Physics · Physics 2026-05-06 Vincenzo Lipardi , Domenica Dibenedetto , Georgios Stamoulis , Mark H. M. Winands

Quantum machine learning (QML) is emerging as an application of quantum computing with the potential to deliver quantum advantage, but its realisation for practical applications remains impeded by challenges. Amongst those, a key barrier is…

Learning low dimensional representation is a crucial issue for many machine learning tasks such as pattern recognition and image retrieval. In this article, we present a quantum algorithm and a quantum circuit to efficiently perform…

Quantum Physics · Physics 2019-03-27 Bojia Duan , Jiabin Yuan , Juan Xu , Dan Li

Access to quantum computing is steadily increasing each year as the speed advantage of quantum computers solidifies with the growing number of usable qubits. However, the inherent noise encountered when running these systems can lead to…

Quantum Physics · Physics 2024-09-24 Jon Gardeazabal-Gutierrez , Erik B. Terres-Escudero , Pablo García Bringas

Recently, the development of quantum chips has made great progress-- the number of qubits is increasing and the fidelity is getting higher. However, qubits of these chips are not always fully connected, which sets additional barriers for…

Emerging Technologies · Computer Science 2018-07-06 Xin Zhang , Hong Xiang , Tao Xiang , Li Fu , Jun Sang

A limited number of qubits, high error rates, and limited qubit connectivity are major challenges for effective near-term quantum computations. Quantum circuit partitioning divides a quantum computation into a set of computations that…

Quantum Physics · Physics 2023-08-21 Sebastian Brandhofer , Ilia Polian , Kevin Krsulich

The resurgence of near-memory processing (NMP) with the advent of big data has shifted the computation paradigm from processor-centric to memory-centric computing. To meet the bandwidth and capacity demands of memory-centric computing, 3D…

Hardware Architecture · Computer Science 2021-04-29 Pritam Majumder , Jiayi Huang , Sungkeun Kim , Abdullah Muzahid , Dylan Siegers , Chia-Che Tsai , Eun Jung Kim

The qubit mapping problem is a challenge in quantum computing that is related to mapping logical qubits to the physical ones on the quantum computer. Due to the diversity of quantum computer topologies and circuits, numerous approaches…

Quantum Physics · Physics 2026-03-03 Gabrielius Keibas , Linas Petkevičius