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Optical coherence tomography (OCT) is a non-invasive imaging technology which can provide micrometer-resolution cross-sectional images of the inner structures of the eye. It is widely used for the diagnosis of ophthalmic diseases with…

Image and Video Processing · Electrical Eng. & Systems 2019-12-10 Donghuan Lu , Morgan Heisler , Da Ma , Setareh Dabiri , Sieun Lee , Gavin Weiguang Ding , Marinko V. Sarunic , Mirza Faisal Beg

Optical tweezers constitute pivotal tools in Atomic, Molecular, and Optical(AMO) physics, facilitating precise trapping and manipulation of individual atoms and molecules. This process affords the capability to generate desired geometries…

Atomic Physics · Physics 2024-01-11 Yongwoong Lee , Eunmi Chae

There is a trend in research towards more automation using smart systems powered by artificial intelligence. While experiments are often challenging to automate, they can greatly benefit from automation by reducing labor and increasing…

Computational methods for electromagnetic and light scattering can be used for the calculation of optical forces and torques. Since typical particles that are optically trapped or manipulated are on the order of the wavelength in size,…

Fast and accurate 3D position detection in optical tweezers (OT) is essential for quantitatively monitoring subtle variations in the mechanical properties of microscopic systems ranging from biomolecules to cells and colloids. Because…

Arthur Ashkin was awarded the 2018 Nobel prize in physics for the invention of optical tweezers. Since the first publication in 1986 Optical Tweezers have been used as a tool to measure forces and rheological properties of microscopic…

Optics · Physics 2019-06-25 Antonio Alvaro Ranha Neves , Carlos Lenz Cesar

Computational modelling has made many useful contributions to the field of optical tweezers. One aspect in which it can be applied is the simulation of the dynamics of particles in optical tweezers. This can be useful for systems with many…

Multi-step assembly of individual protein building blocks is key to the formation of essential higher-order structures inside and outside of cells. Optical tweezers is a technique well suited to investigate the mechanics and dynamics of…

Biological Physics · Physics 2020-08-18 Kathrin Lehmann , Marjan Shayegan , Gerhard A. Blab , Nancy R. Forde

Optical tweezers are powerful tools for high resolution study of surface properties. Such experiments are traditionally performed by studying the active or the brownian fluctuation of trapped particles in the X, Y, Z direction. Here we find…

Optics · Physics 2018-11-13 Rahul Vaipully , Dhanush Bhatt , Anand Dev Ranjan , Basudev Roy

Optical processors, built with "optical neurons", can efficiently perform high-dimensional linear operations at the speed of light. Thus they are a promising avenue to accelerate large-scale linear computations. With the current advances in…

Deep neural networks (DNNs) are reshaping the field of information processing. With their exponential growth challenging existing electronic hardware, optical neural networks (ONNs) are emerging to process DNN tasks in the optical domain…

Optical microrobots actuated by optical tweezers (OT) offer great potential for biomedical applications such as cell manipulation and microscale assembly. These tasks demand accurate three-dimensional perception to ensure precise control in…

Robotics · Computer Science 2025-09-03 Lan Wei , Lou Genoud , Dandan Zhang

Optical tweezers equipped with position detection allow for application of piconewton-scale forces and high-temporal-resolution measurements of nanometer-scale motion. While typically used for trapping microscopic objects, the optical…

We present a cascade deep neural network to segment retinal vessels in volumetric optical coherence tomography (OCT). Two types of knowledge are infused into the network for confining the searching regions. (1) Histology. The retinal…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Liyang Fang , Jianlong Yang , Lei Mou , Huihong Zhang , Zhenjie Chai , Zhi Chen , Jiang Liu

Inverse scattering in optical coherence tomography (OCT) seeks to recover both structural images and intrinsic tissue optical properties, including refractive index, scattering coefficient, and anisotropy. This inverse problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Jinglun Yu , Yaning Wang , Wenhan Guo , Yuan Gao , Yu Sun , Jin U. Kang

Structured optical waveforms are emerging as powerful control fields for the next generation of complex photonic and electromagnetic systems, where the temporal structure of light can determine the ultimate performance of scientific…

Deep learning has rapidly become a widespread tool in both scientific and commercial endeavors. Milestones of deep learning exceeding human performance have been achieved for a growing number of tasks over the past several years, across…

Optical Coherence Tomography (OCT) is one of the most important retinal imaging technique. However, involuntary motion artifacts still pose a major challenge in OCT imaging that compromises the quality of downstream analysis, such as…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Yiqian Wang , Alexandra Warter , Melina Cavichini , Varsha Alex , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

The optical neural network (ONN) is a promising hardware platform for next-generation neuromorphic computing due to its high parallelism, low latency, and low energy consumption. However, previous integrated photonic tensor cores (PTCs)…

Optical tweezers are tools made of light that enable contactless pushing, trapping, and manipulation of objects ranging from atoms to space light sails. Since the pioneering work by Arthur Ashkin in the 1970s, optical tweezers have evolved…

Optics · Physics 2022-06-29 Giovanni Volpe , Onofrio M. Maragò , Halina Rubinzstein-Dunlop , Giuseppe Pesce , Alexander B. Stilgoe , Giorgio Volpe , Georgiy Tkachenko , Viet Giang Truong , Síle Nic Chormaic , Fatemeh Kalantarifard , Parviz Elahi , Mikael Käll , Agnese Callegari , Manuel I. Marqués , Antonio A. R. Neves , Wendel L. Moreira , Adriana Fontes , Carlos L. Cesar , Rosalba Saija , Abir Saidi , Paul Beck , Jörg S. Eismann , Peter Banzer , Thales F. D. Fernandes , Francesco Pedaci , Warwick P Bowen , Rahul Vaippully , Muruga Lokesh , Basudev Roy , Gregor Thalhammer , Monika Ritsch-Marte , Laura Pérez García , Alejandro V. Arzola , Isaac Pérez Castillo , Aykut Argun , Till M. Muenker , Bart E. Vos , Timo Betz , Ilaria Cristiani , Paolo Minzioni , Peter J. Reece , Fan Wang , David McGloin , Justus C. Ndukaife , Romain Quidant , Reece P. Roberts , Cyril Laplane , Thomas Volz , Reuven Gordon , Dag Hanstorp , Javier Tello Marmolejo , Graham D. Bruce , Kishan Dholakia , Tongcang Li , Oto Brzobohatý , Stephen H. Simpson , Pavel Zemánek , Felix Ritort , Yael Roichman , Valeriia Bobkova , Raphael Wittkowski , Cornelia Denz , G. V. Pavan Kumar , Antonino Foti , Maria Grazia Donato , Pietro G. Gucciardi , L. Gardini , G. Bianchi , A. Kashchuk , M. Capitanio , Lynn Paterson , P. H. Jones , Kirstine Berg-Sørensen , Younes F. Barooji , Lene B. Oddershede , Pegah Pouladian , Daryl Preece , Caroline Beck Adiels , Anna Chiara De Luca , A. Magazzù , D. Bronte Ciriza , M. A. Iatì , Grover A. Swartzlander