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We present a novel method for automated identification of putative cell types from single-cell RNA-seq (scRNA-seq) data. By iteratively applying a machine learning approach to an initial clustering of gene expression profiles of a given set…

Quantitative Methods · Quantitative Biology 2020-04-22 Zhichao Miao , Pablo Moreno , Ni Huang , Irene Papatheodorou , Alvis Brazma , Sarah A Teichmann

Test-time adaptation with pre-trained vision-language models has attracted increasing attention for tackling distribution shifts during the test time. Though prior studies have achieved very promising performance, they involve intensive…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Adilbek Karmanov , Dayan Guan , Shijian Lu , Abdulmotaleb El Saddik , Eric Xing

Congenital heart defect (CHD) detection in ultrasound videos is hindered by image noise and probe positioning variability. While automated methods can reduce operator dependence, current machine learning approaches often neglect temporal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Darya Taratynova , Alya Almsouti , Beknur Kalmakhanbet , Numan Saeed , Mohammad Yaqub

While deep learning succeeds in a wide range of tasks, it highly depends on the massive collection of annotated data which is expensive and time-consuming. To lower the cost of data annotation, active learning has been proposed to…

Computer Vision and Pattern Recognition · Computer Science 2021-07-30 Siyu Huang , Tianyang Wang , Haoyi Xiong , Jun Huan , Dejing Dou

Modeling cellular dynamics from single-cell RNA sequencing (scRNA-seq) data is critical for understanding cell development and underlying gene regulatory relationships. Many current methods rely on single-cell velocity to obtain pseudotime,…

Molecular Networks · Quantitative Biology 2024-10-25 Zhen Zhou , Jiachen Li , Hongyi Xin , Xiaoyong Pan , Hong-Bin Shen

Spatial Transcriptomics enables mapping of gene expression within its native tissue context, but current platforms measure only a limited set of genes due to experimental constraints and excessive costs. To overcome this, computational…

Genomics · Quantitative Biology 2025-11-20 Amit Kumar , Maninder Kaur , Raghvendra Mall , Sukrit Gupta

The process algebra tock-CSP provides textual notations for modelling discrete-time behaviours, with the support of various tools for verification. Similarly, automatic verification of Timed Automata (TA) is supported by the real-time…

Logic in Computer Science · Computer Science 2021-04-30 Abdulrazaq Abba , Ana Cavalcanti , Jeremy Jacob

RNA sequencing (RNA-seq) is the conventional genome-scale approach used to capture the expression levels of all detectable genes in a biological sample. This is now regularly used for population-based studies designed to identify genetic…

Genomics · Quantitative Biology 2026-05-25 Christopher Thron , Farhad Jafari

Time series anomaly detection (TSAD) has gained significant attention due to its real-world applications to improve the stability of modern software systems. However, there is no effective way to verify whether they can meet the…

RNA-seq has rapidly become the de facto technique to measure gene expression. However, the time required for analysis has not kept up with the pace of data generation. Here we introduce Sailfish, a novel computational method for quantifying…

Genomics · Quantitative Biology 2014-04-25 Rob Patro , Stephen M. Mount , Carl Kingsford

Surgical phase recognition is a key task in computer-assisted surgery, aiming to automatically identify and categorize the different phases within a surgical procedure. Despite substantial advancements, most current approaches rely on fully…

Computer Vision and Pattern Recognition · Computer Science 2024-06-27 Or Rubin , Shlomi Laufer

Time Series Analysis (TSA) is a critical workload to extract valuable information from collections of sequential data, e.g., detecting anomalies in electrocardiograms. Subsequence Dynamic Time Warping (sDTW) is the state-of-the-art…

In recent years, proposed studies on time-series anomaly detection (TAD) report high F1 scores on benchmark TAD datasets, giving the impression of clear improvements in TAD. However, most studies apply a peculiar evaluation protocol called…

Machine Learning · Computer Science 2022-01-05 Siwon Kim , Kukjin Choi , Hyun-Soo Choi , Byunghan Lee , Sungroh Yoon

Detection of periodic patterns of interest within noisy time series data plays a critical role in various tasks, spanning from health monitoring to behavior analysis. Existing learning techniques often rely on labels or clean versions of…

Machine Learning · Computer Science 2025-06-24 Berken Utku Demirel , Christian Holz

Spiking neural networks have gained significant attention due to their brain-like information processing capabilities. The use of surrogate gradients has made it possible to train spiking neural networks with backpropagation, leading to…

Neural and Evolutionary Computing · Computer Science 2023-05-24 Dongcheng Zhao , Guobin Shen , Yiting Dong , Yang Li , Yi Zeng

Time-series anomaly detection is an important task and has been widely applied in the industry. Since manual data annotation is expensive and inefficient, most applications adopt unsupervised anomaly detection methods, but the results are…

Machine Learning · Computer Science 2023-01-02 Hong Guo , Yujing Wang , Jieyu Zhang , Zhengjie Lin , Yunhai Tong , Lei Yang , Luoxing Xiong , Congrui Huang

Typical techniques for sequence classification are designed for well-segmented sequences which have been edited to remove noisy or irrelevant parts. Therefore, such methods cannot be easily applied on noisy sequences expected in real-world…

Computer Vision and Pattern Recognition · Computer Science 2017-04-18 Wenjie Pei , Tadas Baltrušaitis , David M. J. Tax , Louis-Philippe Morency

Many real-world applications involve multivariate, geo-tagged time series data: at each location, multiple sensors record corresponding measurements. For example, air quality monitoring system records PM2.5, CO, etc. The resulting…

Machine Learning · Computer Science 2019-08-06 Jiawei Ma , Zheng Shou , Alireza Zareian , Hassan Mansour , Anthony Vetro , Shih-Fu Chang

In recent years, dynamic parameterization of acoustic environments has garnered attention in audio processing. This focus includes room volume and reverberation time (RT60), which define local acoustics independent of sound source and…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-10 Chunxi Wang , Maoshen Jia , Meiran Li , Changchun Bao , Wenyu Jin

Although mainstream unsupervised anomaly detection (AD) algorithms perform well in academic datasets, their performance is limited in practical application due to the ideal experimental setting of clean training data. Training with noisy…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Xi Jiang , Ying Chen , Qiang Nie , Yong Liu , Jianlin Liu , Bin-Bin Gao , Jun Liu , Chengjie Wang , Feng Zheng