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A novel time calibration method for waveform sampling application specific integrated circuits (ASICs) based on switched capacitor arrays (SCAs) is proposed in this paper. Precision timing extraction using SCA ASICs has been proved to be a…

Instrumentation and Detectors · Physics 2019-07-10 Boyu Cheng , Lei Zhao , Jiajun Qin , Han Chen , Yuxiang Guo , Shubin Liu , Qi An

Single-cell RNA-seq (scRNA-seq) enables atlas-scale profiling of complex tissues, revealing rare lineages and transient states. Yet, assigning biologically valid cell identities remains a bottleneck because markers are tissue- and…

Single-cell RNA sequencing (scRNA-seq) is a fast growing approach to measure the genome-wide transcriptome of many individual cells in parallel, but results in noisy data with many dropout events. Existing methods to learn molecular…

Quantitative Methods · Quantitative Biology 2018-02-27 Beyrem Khalfaoui , Jean-Philippe Vert

Accurate cell type annotation across datasets is a key challenge in single-cell analysis. snRNA-seq enables profiling of frozen or difficult-to-dissociate tissues, complementing scRNA-seq by capturing fragile or rare cell types. However,…

Genomics · Quantitative Biology 2026-03-10 Xiran Chen , Quan Zou , Qinyu Cai , Xiaofeng Chen , Weikai Li , Yansu Wang

Single-cell RNA sequencing (scRNA-seq) technology enables systematic delineation of cellular states and interactions, providing crucial insights into cellular heterogeneity. Building on this potential, numerous computational methods have…

Genomics · Quantitative Biology 2025-11-11 Ping Xu , Zaitian Wang , Zhirui Wang , Pengjiang Li , Ran Zhang , Gaoyang Li , Hanyu Xie , Jiajia Wang , Yuanchun Zhou , Pengfei Wang

Deep learning methods have shown promising performance in fault diagnosis for multimode process. Most existing studies assume that the collected health state categories from different operating modes are identical. However, in real…

Machine Learning · Computer Science 2025-10-30 Guangqiang Li , M. Amine Atoui , Xiangshun Li

In temporal action segmentation, Timestamp supervision requires only a handful of labelled frames per video sequence. For unlabelled frames, previous works rely on assigning hard labels, and performance rapidly collapses under subtle…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Rahul Rahaman , Dipika Singhania , Alexandre Thiery , Angela Yao

Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the resolution of individual cells, providing unprecedented insights into cellular heterogeneity and complex biological systems. This paper…

Other Quantitative Biology · Quantitative Biology 2024-06-11 Megha Patel , Nimish Magre , Himanshi Motwani , Nik Bear Brown

Temporal action segmentation approaches have been very successful recently. However, annotating videos with frame-wise labels to train such models is very expensive and time consuming. While weakly supervised methods trained using only…

Computer Vision and Pattern Recognition · Computer Science 2021-03-29 Zhe Li , Yazan Abu Farha , Juergen Gall

Test-Time Adaptation (TTA) adjusts models using unlabeled test data to handle dynamic distribution shifts. However, existing methods rely on frequent adaptation and high computational cost, making them unsuitable for resource-constrained…

Machine Learning · Computer Science 2025-11-20 Hyeongheon Cha , Dong Min Kim , Hye Won Chung , Taesik Gong , Sung-Ju Lee

Time series anomaly detection (TSAD) finds many applications such as monitoring environmental sensors, industry KPIs, patient biomarkers, etc. A two-fold challenge for TSAD is a versatile and unsupervised model that can detect various…

Machine Learning · Computer Science 2025-05-07 Boje Deforce , Meng-Chieh Lee , Bart Baesens , Estefanía Serral Asensio , Jaemin Yoo , Leman Akoglu

Nowadays, deep neural networks outperform humans in many tasks. However, if the input distribution drifts away from the one used in training, their performance drops significantly. Recently published research has shown that adapting the…

Machine Learning · Computer Science 2022-05-19 Alexander Bartler , Florian Bender , Felix Wiewel , Bin Yang

Time series anomaly detection (TSAD) has traditionally focused on binary classification and often lacks the fine-grained categorization and explanatory reasoning required for transparent decision-making. To address these limitations, we…

Machine Learning · Computer Science 2026-04-17 Yiyuan Yang , Zichuan Liu , Lei Song , Kai Ying , Zhiguang Wang , Tom Bamford , Svitlana Vyetrenko , Jiang Bian , Qingsong Wen

A new Bayesian software package for the analysis of pulsar timing data is presented in the form of TempoNest which allows for the robust determination of the non-linear pulsar timing solution simultaneously with a range of additional…

Instrumentation and Methods for Astrophysics · Physics 2013-12-04 Lindley Lentati , Paul Alexander , Michael P. Hobson , Farhan Feroz , Rutger van Haasteren , Kejia Lee , Ryan M. Shannon

Test time adaptation (TTA) equips deep learning models to handle unseen test data that deviates from the training distribution, even when source data is inaccessible. While traditional TTA methods often rely on entropy as a confidence…

Machine Learning · Computer Science 2024-09-17 Afshar Shamsi , Rejisa Becirovic , Ahmadreza Argha , Ehsan Abbasnejad , Hamid Alinejad-Rokny , Arash Mohammadi

Cell type identification from single-cell transcriptomic data is a common goal of single-cell RNA sequencing (scRNAseq) data analysis. Neural networks have been employed to identify cell types from scRNAseq data with high performance.…

Genomics · Quantitative Biology 2020-05-11 Xishuang Dong , Shanta Chowdhury , Uboho Victor , Xiangfang Li , Lijun Qian

Spiking Neural Networks (SNNs), as a biologically plausible alternative to Artificial Neural Networks (ANNs), have demonstrated advantages in terms of energy efficiency, temporal processing, and biological plausibility. However, SNNs are…

Machine Learning · Computer Science 2025-09-22 Xinyu Luo , Kecheng Chen , Pao-Sheng Vincent Sun , Chris Xing Tian , Arindam Basu , Haoliang Li

Cell clustering is crucial for uncovering cellular heterogeneity in single-cell RNA sequencing (scRNA-seq) data by identifying cell types and marker genes. Despite its importance, benchmarks for scRNA-seq clustering methods remain…

Genomics · Quantitative Biology 2025-12-03 Ping Xu , Zaitian Wang , Zhirui Wang , Pengjiang Li , Jiajia Wang , Ran Zhang , Pengfei Wang , Yuanchun Zhou

The performance of supervised classification techniques often deteriorates when the data has noisy labels. Even the semi-supervised classification approaches have largely focused only on the problem of handling missing labels. Most of the…

Machine Learning · Computer Science 2022-05-05 Ashit Gupta , Anirudh Deodhar , Tathagata Mukherjee , Venkataramana Runkana

Spiking Neural Networks (SNNs) are promising for low-power computation due to their event-driven mechanism but often suffer from lower accuracy compared to Artificial Neural Networks (ANNs). ANN-to-SNN knowledge distillation can improve SNN…

Artificial Intelligence · Computer Science 2025-01-15 Di Hong , Yueming Wang
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