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Although quantum computing holds promise for solving Combinatorial Optimization Problems (COPs), the limited qubit capacity of NISQ hardware makes large-scale instances intractable. Conventional methods attempt to bridge this gap through…

Quantum Physics · Physics 2026-01-21 Yuhan Huang , Siyuan Jin , Yichi Zhang , Qi Zhao , Jun Qi , Qiming Shao

Variational quantum algorithms (VQAs) are increasingly being applied in simulations of strongly-bound (covalently bonded) systems using full molecular orbital basis representations. The application of quantum computers to the weakly-bound…

A massive gap exists between current quantum computing (QC) prototypes, and the size and scale required for many proposed QC algorithms. Current QC implementations are prone to noise and variability which affect their reliability, and yet…

The rapid expansion of biomolecular datasets presents significant challenges for computational biology. Quantum computing emerges as a promising solution to address these complexities. This study introduces a novel quantum framework for…

Chemical Physics · Physics 2025-07-02 Don Roosan , Rubayat Khan , Saif Nirzhor , Tiffany Khou , Fahmida Hai

A significant hurdle in the noisy intermediate-scale quantum (NISQ) era is identifying functional quantum circuits. These circuits must also adhere to the constraints imposed by current quantum hardware limitations. Variational quantum…

Quantum Physics · Physics 2024-10-03 Akash Kundu

Quantum algorithms offer an exponential speedup over classical algorithms for a range of computational problems. The fundamental mechanisms underlying quantum computation required the development and construction of quantum computers. These…

Emerging Technologies · Computer Science 2025-06-12 Shane Sweeney , Krishnendu Guha

Hybrid quantum-classical machine learning offers a promising direction for advancing automated quality control in industrial settings. In this study, we investigate two hybrid quantum-classical approaches for classifying defects in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Akshaya Srinivasan , Xiaoyin Cheng , Jianming Yi , Alexander Geng , Desislava Ivanova , Andreas Weinmann , Ali Moghiseh

This study explores the intersection of continuous-variable quantum computing (CVQC) and classical machine learning, focusing on CVQC data encoding techniques, including Displacement encoding and squeezing encoding, alongside Instantaneous…

Quantum Physics · Physics 2025-04-10 Minati Rath , Hema Date

Quantum machine learning (QML) has been identified as one of the key fields that could reap advantages from near-term quantum devices, next to optimization and quantum chemistry. Research in this area has focused primarily on variational…

Quantum Physics · Physics 2022-06-01 Andrea Skolik , Sofiene Jerbi , Vedran Dunjko

Quantum mechanics has introduced a new theoretical framework for the study of molecules, enabling the prediction of properties and dynamics through the solution of the Schr\"odinger equation applied to these systems. However, solving this…

Variational quantum algorithms (VQAs) combine the advantages of classical optimization and quantum computation, making them one of the most promising approaches in the Noisy Intermediate-Scale Quantum (NISQ) era. However, when optimized…

Quantum Physics · Physics 2025-11-20 Zhehao Yi , Rahul Bhadani

Quantum kernel methods are a promising branch of quantum machine learning, yet their effectiveness on diverse, high-dimensional, real-world data remains unverified. Current research has largely been limited to low-dimensional or synthetic…

Machine Learning · Computer Science 2026-02-19 Jiang Yuhan , Matthew Otten

Quantum algorithms offer a compelling new avenue for addressing difficult NP-complete optimization problems, such as the Generalized Assignment Problem (GAP). Given the operational constraints of contemporary Noisy Intermediate-Scale…

Quantum Physics · Physics 2025-11-05 Carlo Mastroianni , Francesco Plastina , Jacopo Settino , Andrea Vinci

Despite extensive research efforts, few quantum algorithms for classical optimization demonstrate realizable quantum advantage. The utility of many quantum algorithms is limited by high requisite circuit depth and nonconvex optimization…

Quantum Physics · Physics 2022-01-27 Taylor L. Patti , Jean Kossaifi , Anima Anandkumar , Susanne F. Yelin

Variational quantum algorithms (VQAs) have shown strong evidences to gain provable computational advantages for diverse fields such as finance, machine learning, and chemistry. However, the heuristic ansatz exploited in modern VQAs is…

In recent years, Quantum Computing (QC) has progressed to the point where small working prototypes are available for use. Termed Noisy Intermediate-Scale Quantum (NISQ) computers, these prototypes are too small for large benchmarks or even…

Variational quantum eigensolver (VQE) is promising to show quantum advantage on near-term noisy-intermediate-scale quantum (NISQ) computers. One central problem of VQE is the effect of noise, especially the physical noise on realistic…

Quantum Physics · Physics 2021-09-30 Jinfeng Zeng , Zipeng Wu , Chenfeng Cao , Chao Zhang , Shiyao Hou , Pengxiang Xu , Bei Zeng

There is much debate on whether quantum computing on current NISQ devices, consisting of noisy hundred qubits and requiring a non-negligible usage of classical computing as part of the algorithms, has utility and will ever offer advantages…

Variational quantum circuits (VQCs) are a central component of many quantum machine learning algorithms, offering a hybrid quantum-classical framework that, under certain aspects, can be considered similar to classical deep neural networks.…

Quantum Physics · Physics 2025-07-16 Nicola Assolini , Luca Marzari , Isabella Mastroeni , Alessandra di Pierro

The Variational Quantum Eigensolver (VQE) is a promising algorithm for quantum computing applications in chemistry and materials science, particularly in addressing the limitations of classical methods for complex systems. This study…

Quantum Physics · Physics 2025-02-25 Nia Pollard , Kamal Choudhary
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