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Two-photon laser scanning microscopy is widely used in a quickly growing field of neuroscience. It is a fluorescence imaging technique that allows imaging of living tissue up to a very high depth to study inherent brain structure and…

Applications · Statistics 2018-02-15 Kyongche Kang , Jinsub Hong , Hannah Worrall

Recent advances at the intersection of control theory, neuroscience, and machine learning have revealed novel mechanisms by which dynamical systems perform computation. These advances encompass a wide range of conceptual, mathematical, and…

Machine Learning · Computer Science 2026-04-10 Arthur N. Montanari , Francesco Bullo , Dmitry Krotov , Adilson E. Motter

Advances in experimental neuroscience have transformed our ability to explore the structure and function of neural circuits. At the same time, advances in machine learning have unleashed the remarkable computational power of artificial…

Neurons and Cognition · Quantitative Biology 2021-11-23 SueYeon Chung , L. F. Abbott

Spike-based neuromorphic hardware promises to reduce the energy consumption of image classification and other deep learning applications, particularly on mobile phones or other edge devices. However, direct training of deep spiking neural…

Neural and Evolutionary Computing · Computer Science 2021-01-27 Christoph Stöckl , Wolfgang Maass

The promise of artificial intelligence (AI) to process complex datasets has brought about innovative computing paradigms. While recent developments in quantum-photonic computing have reached significant feats, mimicking our brain's ability…

Optics · Physics 2021-11-23 Vincent R. Daria

To gain a deeper understanding of the behavior and learning dynamics of (deep) artificial neural networks, it is valuable to employ mathematical abstractions and models. These tools provide a simplified perspective on network performance…

Machine Learning · Computer Science 2023-08-03 Stephan Johann Lehmler , Muhammad Saif-ur-Rehman , Tobias Glasmachers , Ioannis Iossifidis

The difference between the chronological and biological brain age of a subject can be an important biomarker for neurodegenerative diseases, thus brain age estimation can be crucial in clinical settings. One way to incorporate multimodal…

Neural population activity relating to behaviour is assumed to be inherently low-dimensional despite the observed high dimensionality of data recorded using multi-electrode arrays. Therefore, predicting behaviour from neural population…

Neurons and Cognition · Quantitative Biology 2022-02-17 Justin Jude , Matthew G Perich , Lee E Miller , Matthias H Hennig

Generative models of brain activity have been instrumental in testing hypothesized mechanisms underlying brain dynamics against experimental datasets. Beyond capturing the key mechanisms underlying spontaneous brain dynamics, these models…

Neurons and Cognition · Quantitative Biology 2024-11-18 Rishikesan Maran , Eli J. Müller , Ben D. Fulcher

Driven by the remarkable breakthroughs during the past decade, photonics neural networks have experienced a revival. Here, we provide a general overview of progress over the past decade, and sketch a roadmap of important future…

Emerging Technologies · Computer Science 2021-07-20 Daniel Brunner , Laurent Larger , Miguel C. Soriano

Computational neuroscience studies that have examined human visual system through functional magnetic resonance imaging (fMRI) have identified a model where the mammalian brain pursues two distinct pathways (for recognition of biological…

Computer Vision and Pattern Recognition · Computer Science 2015-09-15 Bardia Yousefi , C. K. Loo

We present a neural network approach for closed-loop deep brain stimulation (DBS). We cast the problem of finding an optimal neurostimulation strategy as a control problem. In this setting, control policies aim to optimize therapeutic…

Optimization and Control · Mathematics 2023-11-14 Malvern Madondo , Deepanshu Verma , Lars Ruthotto , Nicholas Au Yong

An emerging paradigm proposes that neural computations can be understood at the level of dynamical systems that govern low-dimensional trajectories of collective neural activity. How the connectivity structure of a network determines the…

Neurons and Cognition · Quantitative Biology 2021-05-28 Manuel Beiran , Alexis Dubreuil , Adrian Valente , Francesca Mastrogiuseppe , Srdjan Ostojic

Probabilistic inference offers a principled framework for understanding both behaviour and cortical computation. However, two basic and ubiquitous properties of cortical responses seem difficult to reconcile with probabilistic inference:…

Neurons and Cognition · Quantitative Biology 2017-01-03 Laurence Aitchison , Máté Lengyel

The neuronal paradigm of studying the brain has left us with limitations in both our understanding of how neurons process information to achieve biological intelligence and how such knowledge may be translated into artificial intelligence…

Neurons and Cognition · Quantitative Biology 2020-05-12 Leo Kozachkov , Konstantinos P. Michmizos

Learning interpretable representations of neural dynamics at a population level is a crucial first step to understanding how observed neural activity relates to perception and behavior. Models of neural dynamics often focus on either…

Machine Learning · Statistics 2025-01-13 Noga Mudrik , Yenho Chen , Eva Yezerets , Christopher J. Rozell , Adam S. Charles

It is believed that neural information representation and processing relies on the neural population instead of a single neuron. In neuromorphic photonics, photonic neurons in the form of nonlinear responses have been extensively studied in…

Emerging Technologies · Computer Science 2021-09-28 Bowen Ma , Junfeng Zhang , Weiwen Zou

Photonic Spiking Neural Networks (PSNN) composed of the co-integrated CMOS and photonic elements can offer low loss, low power, highly-parallel, and high-throughput computing for brain-inspired neuromorphic systems. In addition,…

Systems and Control · Electrical Eng. & Systems 2023-11-28 Yun-Jhu Lee , Mehmet Berkay On , Luis El Srouji , Li Zhang , Mahmoud Abdelghany , S. J. Ben Yoo

Models that can actively seek out the best quality training data hold the promise of more accurate, adaptable, and efficient machine learning. Active learning techniques often tend to prefer examples that are the most difficult to classify.…

Machine Learning · Computer Science 2023-07-25 Savya Khosla , Chew Kin Whye , Jordan T. Ash , Cyril Zhang , Kenji Kawaguchi , Alex Lamb

Localized receptive fields -- neurons that are selective for certain contiguous spatiotemporal features of their input -- populate early sensory regions of the mammalian brain. Unsupervised learning algorithms that optimize explicit…

Machine Learning · Computer Science 2025-01-30 Leon Lufkin , Andrew M. Saxe , Erin Grant