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Understanding the role of astrocytes in brain computation is a nascent challenge, promising immense rewards, in terms of new neurobiological knowledge that can be translated into artificial intelligence. In our ongoing effort to identify…

Neurons and Cognition · Quantitative Biology 2018-07-10 Ioannis Polykretis , Vladimir Ivanov , Konstantinos P. Michmizos

The distinct timescales of synaptic plasticity and neural activity dynamics play an important role in the brain's learning and memory systems. Activity-dependent plasticity reshapes neural circuit architecture, determining spontaneous and…

Neurons and Cognition · Quantitative Biology 2023-06-30 Heather L Cihak , Zachary P Kilpatrick

Precise spatio-temporal patterns of neuronal action potentials underly e.g. sensory representations and control of muscle activities. However, it is not known how the synaptic efficacies in the neuronal networks of the brain adapt such that…

Neurons and Cognition · Quantitative Biology 2015-02-24 Christian Albers , Maren Westkott , Klaus Pawelzik

In this study, we propose and analyze in simulations a new, highly flexible method of implementing synaptic plasticity in a wafer-scale, accelerated neuromorphic hardware system. The study focuses on globally modulated STDP, as a special…

Neurons and Cognition · Quantitative Biology 2013-08-21 Simon Friedmann , Nicolas Frémaux , Johannes Schemmel , Wulfram Gerstner , Karlheinz Meier

Neuromorphic Computing is a nascent research field in which models and devices are designed to process information by emulating biological neural systems. Thanks to their superior energy efficiency, analog neuromorphic systems are highly…

Machine Learning · Computer Science 2019-05-30 Tianlin Liu

Neuromorphic computing and spiking neural networks (SNN) mimic the behavior of biological systems and have drawn interest for their potential to perform cognitive tasks with high energy efficiency. However, some factors such as temporal…

Hardware Architecture · Computer Science 2021-05-10 Haowen Fang , Brady Taylor , Ziru Li , Zaidao Mei , Hai Li , Qinru Qiu

Synaptic plasticity, the dynamic tuning of signal transmission strength between neurons, serves as a fundamental basis for memory and learning in biological organisms. This adaptive nature of synapses is considered one of the key features…

Mesoscale and Nanoscale Physics · Physics 2024-11-11 Yechan Noh , Alex Smolyanitsky

Synaptic dynamics, such as long- and short-term plasticity, play an important role in the complexity and biological realism achievable when running neural networks on a neuromorphic IC. For example, they endow the IC with an ability to…

Synaptic plasticity depends on the interaction between electrical activity in neurons and the synaptic proteome, the collection of over 1000 proteins in the post-synaptic density (PSD) of synapses. To construct models of synaptic plasticity…

Neurons and Cognition · Quantitative Biology 2014-11-19 David C. Sterratt , Oksana Sorokina , J. Douglas Armstrong

Cryogenic neuromorphic systems, inspired by the brains unparalleled efficiency, present a promising paradigm for next generation computing architectures.This work introduces a fully integrated neuromorphic framework that combines…

Emerging Technologies · Computer Science 2025-01-15 Md Mazharul Islam , Julia Steed , Karan Patel , Catherine Schuman , Ahmedullah Aziz

Spike Timing Dependent Plasticity is form of learning that has been demonstrated in real cortical tissue, but attempts to use it for artificial systems have not produced good results. This paper seeks to remedy this with two significant…

Neural and Evolutionary Computing · Computer Science 2020-07-01 Simon Davidson , Stephen B. Furber , Oliver Rhodes

Real-time simulation of a large-scale biologically representative spiking neural network is presented, through the use of a heterogeneous parallelisation scheme and SpiNNaker neuromorphic hardware. A published cortical microcircuit model is…

Emerging Technologies · Computer Science 2021-04-28 Oliver Rhodes , Luca Peres , Andrew G. D. Rowley , Andrew Gait , Luis A. Plana , Christian Brenninkmeijer , Steve B. Furber

Learning is based on synaptic plasticity, which affects and is driven by neural activity. Because pre- and postsynaptic spiking activity is shaped by randomness, the synaptic weights follow a stochastic process, requiring a probabilistic…

Neurons and Cognition · Quantitative Biology 2026-01-14 Jakob Stubenrauch , Naomi Auer , Richard Kempter , Benjamin Lindner

Electrophysiological techniques have improved substantially over the past years to the point that neuroprosthetics applications are becoming viable. This evolution has been fuelled by the advancement of implantable microelectrode…

Emerging Technologies · Computer Science 2017-07-28 Isha Gupta , Alexantrou Serb , Ali Khiat , Maria Trapatseli , Themistoklis Prodromakis

Compact models of memristors are essential for simulating large-scale neuromorphic systems, yet they often do not include description of complex dynamics like volatile relaxation and synaptic plasticity. We introduce a modular,…

Neuromorphic computing has emerged as a promising avenue towards building the next generation of intelligent computing systems. It has been proposed that memristive devices, which exhibit history-dependent conductivity modulation, could…

Achieving personalized intelligence at the edge with real-time learning capabilities holds enormous promise in enhancing our daily experiences and helping decision making, planning, and sensing. However, efficient and reliable edge learning…

Neural and Evolutionary Computing · Computer Science 2024-08-29 Kenneth Stewart , Michael Neumeier , Sumit Bam Shrestha , Garrick Orchard , Emre Neftci

A growing body of work underlines striking similarities between biological neural networks and recurrent, binary neural networks. A relatively smaller body of work, however, discusses similarities between learning dynamics employed in deep…

Neural and Evolutionary Computing · Computer Science 2020-05-22 Jacques Kaiser , Hesham Mostafa , Emre Neftci

Neuromorphic architectures offer great promise for achieving computation capacities beyond conventional Von Neumann machines. The essential elements for achieving this vision are highly scalable synaptic mimics that do not undermine…

Emerging Technologies · Computer Science 2015-07-09 Radu Berdan , Eleni Vasilaki , Ali Khiat , Giacomo Indiveri , Alexandru Serb , Themistoklis Prodromakis

Neuromorphic computing uses brain-inspired principles to design circuits that can perform computational tasks with superior power efficiency to conventional computers. Approaches that use traditional electronic devices to create artificial…

Applied Physics · Physics 2020-07-14 J. Grollier , D. Querlioz , K. Y. Camsari , K. Everschor-Sitte , S. Fukami , M. D. Stiles