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Related papers: WSI-LLaVA: A Multimodal Large Language Model for W…

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Multi-modal large language models (MLLMs) have shown promise in advancing healthcare. However, most existing models remain confined to single-image understanding, which greatly limits their applicability in clinical workflows. In practice,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Zhen Chen , Yihang Fu , Gabriel Madera , Mauro Giuffre , Serina Applebaum , Hyunjae Kim , Hua Xu , Qingyu Chen

Large Language Models (LLMs) have shown significant promise across various natural language processing tasks. However, their application in the field of pathology, particularly for extracting meaningful insights from unstructured medical…

Computation and Language · Computer Science 2025-03-04 Rachit Saluja , Jacob Rosenthal , Yoav Artzi , David J. Pisapia , Benjamin L. Liechty , Mert R. Sabuncu

Determining lymphoma subtypes is a crucial step for better patient treatment targeting to potentially increase their survival chances. In this context, the existing gold standard diagnosis method, which relies on gene expression technology,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Marianne Petit , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard

Large Vision-Language Models (LVLMs) have demonstrated remarkable capabilities in various multimodal tasks. However, their potential in the medical domain remains largely unexplored. A significant challenge arises from the scarcity of…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Yutao Hu , Tianbin Li , Quanfeng Lu , Wenqi Shao , Junjun He , Yu Qiao , Ping Luo

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

How similar are two images? In computational pathology, where Whole Slide Images (WSIs) of digitally scanned tissue samples from patients can be multi-gigapixels in size, determination of degree of similarity between two WSIs is a…

Image and Video Processing · Electrical Eng. & Systems 2023-01-24 Piotr Keller , Muhammad Dawood , Fayyaz ul Amir Afsar Minhas

Whole Slide Images (WSIs) or histopathology images are used in digital pathology. WSIs pose great challenges to deep learning models for clinical diagnosis, owing to their size and lack of pixel-level annotations. With the recent…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Soham Rohit Chitnis , Sidong Liu , Tirtharaj Dash , Tanmay Tulsidas Verlekar , Antonio Di Ieva , Shlomo Berkovsky , Lovekesh Vig , Ashwin Srinivasan

Pathological captioning of Whole Slide Images (WSIs), though is essential in computer-aided pathological diagnosis, has rarely been studied due to the limitations in datasets and model training efficacy. In this paper, we propose a new…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Wenkang Qin , Rui Xu , Peixiang Huang , Xiaomin Wu , Heyu Zhang , Lin Luo

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

Computation and Language · Computer Science 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

Pathology is essential for cancer diagnosis, with multiple instance learning (MIL) widely used for whole slide image (WSI) analysis. WSIs exhibit a natural hierarchy -- patches, regions, and slides -- with distinct semantic associations.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Peixiang Huang , Yanyan Huang , Weiqin Zhao , Junjun He , Lequan Yu

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Recent advancements indicate that scaling up Multimodal Large Language Models (MLLMs) effectively enhances performance on downstream multimodal tasks. The prevailing MLLM paradigm, \emph{e.g.}, LLaVA, transforms visual features into…

Artificial Intelligence · Computer Science 2024-03-21 Wenqiao Zhang , Tianwei Lin , Jiang Liu , Fangxun Shu , Haoyuan Li , Lei Zhang , He Wanggui , Hao Zhou , Zheqi Lv , Hao Jiang , Juncheng Li , Siliang Tang , Yueting Zhuang

Recently, large language models (LLMs) have taken the spotlight in natural language processing. Further, integrating LLMs with vision enables the users to explore emergent abilities with multimodal data. Visual language models (VLMs), such…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Minh-Hao Van , Prateek Verma , Xintao Wu

Pathology foundation models (PFMs) have emerged as a core approach for learning transferable representations from whole slide images (WSIs), and they are typically benchmarked through downstream clinical endpoints. While such task level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Bokai Zhao , Yiyang Zhang , Yuanchi Zhu , Hanqing Chao , Long Bai , Tai Ma , Minfeng Xu , Ming Song , Tianzi Jiang

Whole-slide images (WSI) in computational pathology have high resolution with gigapixel size, but are generally with sparse regions of interest, which leads to weak diagnostic relevance and data inefficiency for each area in the slide. Most…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Boxuan Zhao , Jun Zhang , Deheng Ye , Jian Cao , Xiao Han , Qiang Fu , Wei Yang

Although great progress has been made by previous table understanding methods including recent approaches based on large language models (LLMs), they rely heavily on the premise that given tables must be converted into a certain text…

Computation and Language · Computer Science 2024-06-13 Mingyu Zheng , Xinwei Feng , Qingyi Si , Qiaoqiao She , Zheng Lin , Wenbin Jiang , Weiping Wang

Multimodal large language models (LLMs) have achieved notable success across various domains, while research in the medical field has largely focused on unimodal images. Meanwhile, current general-domain multimodal models for videos still…

Computer Vision and Pattern Recognition · Computer Science 2024-08-16 Jiajie Li , Garrett Skinner , Gene Yang , Brian R Quaranto , Steven D Schwaitzberg , Peter C W Kim , Jinjun Xiong

Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. The first stage identifies areas of interest (e.g. tumor tissue), while the second stage processes…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Marvin Teichmann , Andre Aichert , Hanibal Bohnenberger , Philipp Ströbel , Tobias Heimann

The emergence of large multimodal models has unlocked remarkable potential in AI, particularly in pathology. However, the lack of specialized, high-quality benchmark impeded their development and precise evaluation. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yuxuan Sun , Hao Wu , Chenglu Zhu , Sunyi Zheng , Qizi Chen , Kai Zhang , Yunlong Zhang , Dan Wan , Xiaoxiao Lan , Mengyue Zheng , Jingxiong Li , Xinheng Lyu , Tao Lin , Lin Yang

Multi-modal large language models (MLLMs) have made significant strides in various visual understanding tasks. However, the majority of these models are constrained to process low-resolution images, which limits their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Xiangyu Zhao , Xiangtai Li , Haodong Duan , Haian Huang , Yining Li , Kai Chen , Hua Yang