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Segmentation networks are not explicitly imposed to learn global invariants of an image, such as the shape of an object and the geometry between multiple objects, when they are trained with a standard loss function. On the other hand,…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Seher Ozcelik , Sinan Unver , Ilke Ali Gurses , Rustu Turkay , Cigdem Gunduz-Demir

Segmenting curvilinear structures in medical images is essential for analyzing morphological patterns in clinical applications. Integrating topological properties, such as connectivity, improves segmentation accuracy and consistency.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Zhuangzhi Gao , Feixiang Zhou , He Zhao , Xiuju Chen , Xiaoxin Li , Qinkai Yu , Yitian Zhao , Alena Shantsila , Gregory Y. H. Lip , Eduard Shantsila , Yalin Zheng

Blood vessel segmentation is one of the most studied topics in computer vision, due to its relevance in daily clinical practice. Despite the evolution the field has been facing, especially after the dawn of deep learning, important…

Image and Video Processing · Electrical Eng. & Systems 2021-08-02 R. J. Araújo , J. S. Cardoso , H. P. Oliveira

In semi-supervised segmentation, capturing meaningful semantic structures from unlabeled data is essential. This is particularly challenging in histopathology image analysis, where objects are densely distributed. To address this issue, we…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Meilong Xu , Xiaoling Hu , Shahira Abousamra , Chen Li , Chao Chen

Getting precise aspects of road through segmentation from remote sensing imagery is useful for many real-world applications such as autonomous vehicles, urban development and planning, and achieving sustainable development goals. Roads are…

Computer Vision and Pattern Recognition · Computer Science 2023-09-28 Javed Iqbal , Aliza Masood , Waqas Sultani , Mohsen Ali

Accurate segmentation of topological tubular structures, such as blood vessels and roads, is crucial in various fields, ensuring accuracy and efficiency in downstream tasks. However, many factors complicate the task, including thin local…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Yaolei Qi , Yuting He , Xiaoming Qi , Yuan Zhang , Guanyu Yang

Computational topology provides a tool, persistent homology, to extract quantitative descriptors from structured objects (images, graphs, point clouds, etc). These descriptors can then be involved in optimization problems, typically as a…

Computational Geometry · Computer Science 2026-03-27 Mathieu Carriere , Yuichi Ike , Théo Lacombe , Naoki Nishikawa

While conventional computer vision emphasizes pixel-level and feature-based objectives, medical image analysis of intricate biological structures necessitates explicit representation of their complex topological properties. Despite their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Yousef Yeganeh , Rui Xiao , Goktug Guvercin , Nassir Navab , Azade Farshad

Accurate segmentation of long and thin tubular structures is required in a wide variety of areas such as biology, medicine, and remote sensing. The complex topology and geometry of such structures often pose significant technical…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Jiaxing Huang , Yanfeng Zhou , Yaoru Luo , Guole Liu , Heng Guo , Ge Yang

Although image denoising algorithms have attracted significant research attention, surprisingly few have been proposed for, or evaluated on, noise from imagery acquired under real low-light conditions. Moreover, noise characteristics are…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Alexandra Malyugina , Nantheera Anantrasirichai , David Bull

Persistent Homology (PH) has been successfully used to train networks to detect curvilinear structures and to improve the topological quality of their results. However, existing methods are very global and ignore the location of topological…

Computer Vision and Pattern Recognition · Computer Science 2022-12-27 Doruk Oner , Adélie Garin , Mateusz Koziński , Kathryn Hess , Pascal Fua

Variational models are widely used in image segmentation, with various models designed to address different types of images by optimizing specific objective functionals. However, traditional segmentation models primarily focus on the visual…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Lingyun Deng , Litong Liu , Dong Wang , Xiao-Ping Wang

Accurately segmenting thin tubular structures, such as vessels, nerves, roads or concrete cracks, is a crucial task in computer vision. Standard deep learning-based segmentation loss functions, such as Dice or Cross-Entropy, focus on…

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

The efficacy of segmentation algorithms is frequently compromised by topological errors like overlapping regions, disrupted connections, and voids. To tackle this problem, we introduce a novel loss function, namely Topology-Aware Focal Loss…

Image and Video Processing · Electrical Eng. & Systems 2023-04-28 Andac Demir , Elie Massaad , Bulent Kiziltan

Understanding how segmentation performance scales with training data is fundamental for developing data-efficient medical AI systems. In this study, we systematically revisit data scaling behavior across 15 anatomical segmentation tasks…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yuetan Chu , Zhongyi Han , Gongning Luo , Xin Gao

Tomography is a widely used tool for analyzing microstructures in three dimensions (3D). The analysis, however, faces difficulty because the constituent materials produce similar grey-scale values. Sometimes, this prompts the image…

Materials Science · Physics 2021-09-28 Anand V. Patel , Tao Hou , Juan D. Beltran Rodriguez , Tamal K. Dey , Dunbar P. Birnie

Retinal fundus photography enhancement is important for diagnosing and monitoring retinal diseases. However, early approaches to retinal image enhancement, such as those based on Generative Adversarial Networks (GANs), often struggle to…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Xuanzhao Dong , Wenhui Zhu , Xin Li , Guoxin Sun , Yi Su , Oana M. Dumitrascu , Yalin Wang

Geometric data augmentation is widely used in segmentation workflows, but polygon annotations are often assumed to remain valid after transformation. This assumption can fail in structured domains such as architectural floorplan analysis,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Sudip Laudari , Sang Hun Baek