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Colorectal liver metastases (CRLM) are a major cause of cancer-related mortality, and reliable detection on CT remains challenging in multi-centre settings. We developed a foundation model-based AI pipeline for patient-level classification…

Prognostic evaluation in patients with colorectal liver metastases (CRLM) remains challenging due to suboptimal accuracy of conventional clinical models. This study developed and validated a robust machine learning model for predicting…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Qinlong Li , Pu Sun , Guanlin Zhu , Tianjiao Liang , Honggang QI

Colorectal cancer frequently metastasizes to the liver, significantly reducing long-term survival. While surgical resection is the only potentially curative treatment for colorectal liver metastasis (CRLM), patient outcomes vary widely…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Muhammad Alberb , Helen Cheung , Anne Martel

Colorectal cancer liver metastases (CLM) are the most common type of distant metastases originating from the abdomen and are characterized by a high recurrence rate after curative resection. It has been previously reported that CLM…

Quantitative Methods · Quantitative Biology 2023-03-09 Ralph Saber , David Henault , Rolando Rebolledo , Simon Turcotte , Samuel Kadoury

Postoperative prognostic prediction for colorectal cancer liver metastasis (CRLM) remains challenging due to tumor heterogeneity, dynamic evolution of the hepatic microenvironment, and insufficient multimodal data fusion. To address these…

Image and Video Processing · Electrical Eng. & Systems 2025-03-14 Zesheng Li , Wei Yang , Yan Su , Yiran Zhu , Yuhan Tang , Haoran Chen , Chengchang Pan , Honggang Qi

Colorectal cancer liver metastasis (CRLM) exhibits high postoperative recurrence and pronounced prognostic heterogeneity, challenging individualized management. Existing prognostic approaches often rely on static representations from a…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Wei Yang , Yiran Zhu , Yan su , Zesheng Li , Chengchang Pan , Honggang Qi

The liver is the most involved organ by distant metastasis in colon-rectal cancer (CRC) patients and it comes necessary to be aware of the mutational status of the lesions to correctly design the best individual treatment. So far, efforts…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Daniele Perlo , Luca Berton , Alessia Delpiano , Francesca Menchini , Stefano Tibaldi , Marco Grosso , Paolo Fonio

Small liver lesions common to colorectal liver metastases (CRLMs) are challenging for convolutional neural network (CNN) segmentation models, especially when we have a wide range of slice thicknesses in the computed tomography (CT) scans.…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Mohammad Hamghalam , Richard K. G. Do , Amber L. Simpson

While colorectal liver metastasis (CRLM) is potentially curable via hepatectomy, patient outcomes remain highly heterogeneous. Postoperative survival prediction is necessary to avoid non-beneficial surgeries and guide personalized therapy.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Muhammad Alberb , Jianan Chen , Hossam El-rewaidy , Paul Karanicolas , Arun Seth , Yutaka Amemiya , Anne Martel , Helen Cheung

Introduction: Accurate intraoperative delineation of colorectal liver metastases (CRLM) is crucial for achieving negative resection margins but remains challenging using intraoperative ultrasound (iUS) due to low contrast, noise, and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Tiziano Natali , Karin A. Olthof , Niels F. M. Kok , Koert F. D. Kuhlmann , Theo J. M. Ruers , Matteo Fusaglia

Colorectal liver metastasis is one of most aggressive liver malignancies. While the definition of lesion type based on CT images determines the diagnosis and therapeutic strategy, the discrimination between cancerous and non-cancerous…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Francisco Perdigon Romero , Andre Diler , Gabriel Bisson-Gregoire , Simon Turcotte , Real Lapointe , Franck Vandenbroucke-Menu , An Tang , Samuel Kadoury

Automated segmentation tools often encounter accuracy and adaptability issues when applied to images of different pathology. The purpose of this study is to explore the feasibility of building a workflow to efficiently route images to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-06 Peilong Wang , Timothy L. Kline , Andy D. Missert , Cole J. Cook , Matthew R. Callstrom , Alex Chan , Robert P. Hartman , Zachary S. Kelm , Panagiotis Korfiatis

This paper proposes a novel multimodal deep learning framework integrating bidirectional LSTM, multi-head attention mechanism, and variational mode decomposition (BiLSTM-AM-VMD) for early liver cancer diagnosis. Using heterogeneous data…

Machine Learning · Computer Science 2025-09-03 Cheng Cheng , Zeping Chen , Xavier Wang

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related deaths worldwide. Most CRC deaths are the result of progression of metastases. The assessment of metastases is done using the RECIST…

Image and Video Processing · Electrical Eng. & Systems 2019-07-19 Xin J. Hunt , Ralph Abbey , Ricky Tharrington , Joost Huiskens , Nina Wesdorp

Primary tumors have a high likelihood of developing metastases in the liver and early detection of these metastases is crucial for patient outcome. We propose a method based on convolutional neural networks (CNN) to detect liver metastases.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-16 Mariëlle J. A. Jansen , Hugo J. Kuijf , Maarten Niekel , Wouter B. Veldhuis , Frank J. Wessels , Max A. Viergever , Josien P. W. Pluim

The most deadly and life-threatening disease in the world is lung cancer. Though early diagnosis and accurate treatment are necessary for lowering the lung cancer mortality rate. A computerized tomography (CT) scan-based image is one of the…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Muntasir Mamun , Md Ishtyaq Mahmud , Mahabuba Meherin , Ahmed Abdelgawad

Colorectal cancer (CRC) is a leading worldwide cause of cancer-related mortality, and the role of prompt precise detection is of paramount interest in improving patient outcomes. Conventional diagnostic methods such as colonoscopy and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-29 Ovi Sarkar , Md Shafiuzzaman , Md. Faysal Ahamed , Golam Mahmud , Muhammad E. H. Chowdhury

Colorectal cancer (CRC) remains the third most prevalent malignancy globally, with approximately 154,000 new cases and 54,000 projected deaths anticipated for 2025. The recent advancement of foundation models in computational pathology has…

Computer Vision and Pattern Recognition · Computer Science 2025-10-17 Usama Sajjad , Abdul Rehman Akbar , Ziyu Su , Deborah Knight , Wendy L. Frankel , Metin N. Gurcan , Wei Chen , Muhammad Khalid Khan Niazi
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