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Related papers: CellSeg1: Robust Cell Segmentation with One Traini…

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In recent years, several unsupervised cell segmentation methods have been presented, trying to omit the requirement of laborious pixel-level annotations for the training of a cell segmentation model. Most if not all of these methods handle…

Computer Vision and Pattern Recognition · Computer Science 2023-12-04 Mehdi Naouar , Gabriel Kalweit , Anusha Klett , Yannick Vogt , Paula Silvestrini , Diana Laura Infante Ramirez , Roland Mertelsmann , Joschka Boedecker , Maria Kalweit

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyper-parameters in…

Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Anwai Archit , Luca Freckmann , Constantin Pape

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

Cell segmentation for multi-modal microscopy images remains a challenge due to the complex textures, patterns, and cell shapes in these images. To tackle the problem, we first develop an automatic cell classification pipeline to label the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Wei Lou , Xinyi Yu , Chenyu Liu , Xiang Wan , Guanbin Li , Siqi Liu , Haofeng Li

Cell segmentation is a fundamental task in microscopy image analysis. Several foundation models for cell segmentation have been introduced, virtually all of them are extensions of Segment Anything Model (SAM), improving it for microscopy…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Anwai Archit , Constantin Pape

Semantic segmentation of microscopic cell images using deep learning is an important technique, however, it requires a large number of images and ground truth labels for training. To address the above problem, we consider an efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Sota Kato , Kazuhiro Hotta

Cellular image segmentation is essential for quantitative biology yet remains difficult due to heterogeneous modalities, morphological variability, and limited annotations. We present GenCellAgent, a training-free multi-agent framework that…

Quantitative Methods · Quantitative Biology 2026-05-12 Xi Yu , Yang Yang , Qun Liu , Yonghua Du , Sean McSweeney , Yuewei Lin

Semi-supervised learning (SSL) has become a promising solution to alleviate the annotation burden of deep learning-based medical image segmentation models. While recent advances in foundation model-driven SSL have pushed the boundary to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yichi Zhang , Le Xue , Bichun Xu , Judong Luo , Zhigang Wu , Yu Fu , Zixin Hu , Yuan Cheng , Yuan Qi

Computer-assisted quantitative analysis on Giga-pixel pathology images has provided a new avenue in histology examination. The innovations have been largely focused on cancer pathology (i.e., tumor segmentation and characterization). In…

Image and Video Processing · Electrical Eng. & Systems 2022-03-24 Ruining Deng , Quan Liu , Can Cui , Zuhayr Asad , Haichun Yang , Yuankai Huo

Two of the most common tasks in medical imaging are classification and segmentation. Either task requires labeled data annotated by experts, which is scarce and expensive to collect. Annotating data for segmentation is generally considered…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Ozan Ciga , Anne L. Martel

Medical image segmentation is vital for clinical diagnosis and quantitative analysis, yet remains challenging due to the heterogeneity of imaging modalities and the high cost of pixel-level annotations. Although general interactive…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yujie Lu , Jingwen Li , Sibo Ju , Yanzhou Su , he yao , Yisong Liu , Min Zhu , Junlong Cheng

Segment Anything Model (SAM) has emerged as a transformative approach in image segmentation, acclaimed for its robust zero-shot segmentation capabilities and flexible prompting system. Nonetheless, its performance is challenged by images…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Wei-Ting Chen , Yu-Jiet Vong , Sy-Yen Kuo , Sizhuo Ma , Jian Wang

We investigate image segmentation of cells under the lens of scalar fields. Our goal is to learn a continuous scalar field on image domains such that its segmentation produces robust instances for cells present in images. This field is a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Kevin I. Ruiz Vargas , Gabriel G. Galdino , Tsang Ing Ren , Alexandre L. Cunha

We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach

Obtaining large-scale medical data, annotated or unannotated, is challenging due to stringent privacy regulations and data protection policies. In addition, annotating medical images requires that domain experts manually delineate…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Tushar Kataria , Shireen Y. Elhabian

The Segment Anything Model (SAM) is a recently developed large model for general-purpose segmentation for computer vision tasks. SAM was trained using 11 million images with over 1 billion masks and can produce segmentation results for a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Yizhe Zhang , Tao Zhou , Shuo Wang , Peixian Liang , Danny Z. Chen

Increasing data set sizes of 3D microscopy imaging experiments demand for an automation of segmentation processes to be able to extract meaningful biomedical information. Due to the shortage of annotated 3D image data that can be used for…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Dennis Eschweiler , Richard S. Smith , Johannes Stegmaier

Medical image segmentation is a critical component in clinical practice, facilitating accurate diagnosis, treatment planning, and disease monitoring. However, existing methods, often tailored to specific modalities or disease types, lack…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Jun Ma , Yuting He , Feifei Li , Lin Han , Chenyu You , Bo Wang

Comprehensive semantic segmentation on renal pathological images is challenging due to the heterogeneous scales of the objects. For example, on a whole slide image (WSI), the cross-sectional areas of glomeruli can be 64 times larger than…

Image and Video Processing · Electrical Eng. & Systems 2023-01-20 Ruining Deng , Quan Liu , Can Cui , Tianyuan Yao , Jun Long , Zuhayr Asad , R. Michael Womick , Zheyu Zhu , Agnes B. Fogo , Shilin Zhao , Haichun Yang , Yuankai Huo
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