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Cell-level dense prediction is central to computational pathology, but remains challenging due to fine-grained histological structures, strong domain shifts, and costly dense annotations. Existing ViT-based pathology foundation models rely…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Weiming Chen , Xitong Ling , Zhenyang Cai , Xidong Wang , Jiawen Li , Tian Guan , Benyou Wang , Yonghong He

The developed computational approach is capable of initiating and propagating cracks inside materials and along material interfaces of general multi-domain structures under quasi-static conditions. Special attention is paid to particular…

Computational Engineering, Finance, and Science · Computer Science 2023-08-23 Roman Vodička

We study how the loading rate, specimen geometry and microstructural texture select the dynamics of a crack moving through an heterogeneous elastic material in the quasi-static approximation. We find a transition, fully controlled by two…

Statistical Mechanics · Physics 2013-09-23 Jonathan Barés , Luc Barbier , Daniel Bonamy

Tracer diffusion and hydrodynamic dispersion in two-dimensional fractures with self-affine roughness is studied by analytic and numerical methods. Numerical simulations were performed via the lattice-Boltzmann approach, using a new boundary…

Statistical Mechanics · Physics 2016-08-31 German Drazer , Joel Koplik

This paper considers the reconstruction of a defect in a two-dimensional waveguide during non-destructive ultrasonic inspection using a derivative-based optimization approach. The propagation of the mechanical waves is simulated by the…

Numerical Analysis · Mathematics 2022-09-07 Jannis Bulling , Benjamin Jurgelucks , Jens Prager , Andrea Walther

We propose a machine learning approach to address a key challenge in materials science: predicting how fractures propagate in brittle materials under stress, and how these materials ultimately fail. Our methods use deep learning and train…

In this paper we study scattering of two-dimensional massless Dirac fermions by a potential that depends on a single Cartesian variable. Depending on the energy of the incoming particle and its angle of incidence, there are three different…

Mesoscale and Nanoscale Physics · Physics 2013-04-30 K. J. A. Reijnders , T. Tudorovskiy , M. I. Katsnelson

We present a novel constitutive model using the framework of strain-limiting theories of elasticity for an evolution of quasi-static anti-plane fracture. The classical linear elastic fracture mechanics (LEFM), with conventional linear…

Computational Engineering, Finance, and Science · Computer Science 2020-07-22 Hyun C. Yoon , Sanghyun Lee , S. M. Mallikarjunaiah

This paper is concerned with the uniqueness, existence, comparison principle and long-time behavior of solutions to the initial-boundary value problem for a unidirectional diffusion equation. The unidirectional evolution often appears in…

Analysis of PDEs · Mathematics 2015-01-07 Goro Akagi , Masato Kimura

When they are damaged or injured, soft biological tissues are able to self-repair and heal. Mechanics is critical during the healing process, as the damaged extracellular matrix (ECM) tends to be replaced with a new undamaged ECM supporting…

Computational Engineering, Finance, and Science · Computer Science 2021-12-08 Di Zuo , Yiqian He , Stéphane Avril , Haitian Yang , Klaus Hackl

Statistics and thermally activated dynamics of crack nucleation and propagation in a two-dimensional heterogeneous material containing quenched randomly distributed defects are studied theoretically. Using the generalized Griffith criterion…

Disordered Systems and Neural Networks · Physics 2010-10-28 J. Kierfeld , V. M. Vinokur

We study the acoustic emission produced by micro-cracks using a two-dimensional disordered lattice model of dynamic fracture, which allows to relate the acoustic response to the internal damage of the sample. We find that the distributions…

Soft Condensed Matter · Physics 2009-11-07 Manuela Minozzi , Guido Caldarelli , Luciano Pietronero , Stefano Zapperi

Synthesizing fully developed three-dimensional turbulent velocity fields remains a long-standing problem in fluid mechanics and an open challenge for generative modeling. The difficulty arises from the coexistence of extreme dimensionality,…

Fluid Dynamics · Physics 2026-03-16 Tianyi Li , Michele Buzzicotti , Fabio Bonaccorso , Luca Biferale

We introduce the Linearized Diffusion Map (LDM), a novel linear dimensionality reduction method constructed via a linear approximation of the diffusion-map kernel. LDM integrates the geometric intuition of diffusion-based nonlinear methods…

Machine Learning · Computer Science 2025-07-22 Julio Candanedo

The dynamics of a crack propagating in an elastic inhomogeneous material is investigated. The variations of the average crack velocity with the external loading are measured for a brittle rock and are shown to display two distinct regimes:…

Statistical Mechanics · Physics 2008-12-18 Laurent Ponson

The fracture simulation of random particle reinforced composite structures remains a challenge. Current techniques either assumed a homogeneous model, ignoring the microstructure characteristics of composite structures, or considered a…

Numerical Analysis · Mathematics 2022-12-23 Zihao Yang , Shaoqi Zheng , Shangkun Shen , Fei Han

Diffusion models produce impressive results in modalities ranging from images and video to protein design and text. However, generating samples with user-specified properties remains a challenge. Recent research proposes fine-tuning models…

Machine Learning · Computer Science 2025-07-21 Raghav Singhal , Zachary Horvitz , Ryan Teehan , Mengye Ren , Zhou Yu , Kathleen McKeown , Rajesh Ranganath

Cracks, the major vehicle for material failure, tend to accelerate to high velocities in brittle materials. In three-dimensions, cracks generically undergo a micro-branching instability at about 40% of their sonic limiting velocity. Recent…

Soft Condensed Matter · Physics 2017-12-06 Chih-Hung Chen , Eran Bouchbinder , Alain Karma

Highly-deformable materials, from synthetic hydrogels to biological tissues, are becoming increasingly important from both fundamental and practical perspectives. Their mechanical behaviors, in particular the dynamics of crack propagation…

Materials Science · Physics 2015-06-09 Tamar Goldman Boué , Roi Harpaz , Jay Fineberg , Eran Bouchbinder

A comparative study of fracture in Al is carried out by using quantum mechanical and empirical atomistic description of atomic interaction at crack tip. The former is accomplished with the density functional theory (DFT) based…

Mesoscale and Nanoscale Physics · Physics 2011-05-20 Qing Peng , Gang Lu