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The function of the organism hinges on the performance of its information-processing networks, which convey information via molecular recognition. Many paths within these networks utilize molecular codebooks, such as the genetic code, to…

Biomolecules · Quantitative Biology 2010-07-27 Tsvi Tlusty

We investigate the consensus problem in a network where nodes communicate via diffusion-based molecular communication (DbMC). In DbMC, messages are conveyed via the variation in the concentration of molecules in the medium. Every node…

Information Theory · Computer Science 2011-03-03 Arash Einolghozati , Mohsen Sardari , Ahmad Beirami , Faramarz Fekri

We consider anomalous diffusion for molecular communication with a passive receiver. We first consider the probability density function of molecules' location at a given time in a space of arbitrary dimension. The expected number of…

Information Theory · Computer Science 2021-07-09 Dung Phuong Trinh , Youngmin Jeong , Sang-Hyo Kim

Biological cells are often found to sense their chemical environment near the single-molecule detection limit. Surprisingly, this precision is higher than simple estimates of the fundamental physical limit, hinting towards active sensing…

Biological Physics · Physics 2015-11-06 Gerardo Aquino , Luke Tweedy , Doris Heinrich , Robert G. Endres

For nano-scale communications, there must be cooperation and simultaneous communication between nano devices. To this end, in this paper we investigate two-way (a.k.a. bi-directional) molecular communications between nano devices. If…

Emerging Technologies · Computer Science 2020-05-06 Jong Woo Kwak , H. Birkan Yilmaz , Nariman Farsad , Chan-Byoung Chae , Andrea Goldsmith

Radio communication over interstellar distances is studied, accounting for noise, dispersion, scattering and motion. Large transmitted powers suggest maximizing power efficiency (ratio of information rate to average signal power) as opposed…

Instrumentation and Methods for Astrophysics · Physics 2016-03-01 David G. Messerschmitt

Living cells use readout molecules to record the state of receptor proteins, similar to measurements or copies in typical computational devices. But is this analogy rigorous? Can cells be optimally efficient, and if not, why? We show that,…

Molecular Networks · Quantitative Biology 2017-04-12 Thomas E. Ouldridge , Christopher C. Govern , Pieter Rein ten Wolde

Cells control their size to cope with noise during growth and division. Eukaryotic cells exhibiting "sizer" control (targeting a specific size before dividing) may rely on molecular concentration thresholds, but simple implementations of…

Biological Physics · Physics 2026-05-08 Motasem ElGamel , Lucas Ribaudo , Andrew Mugler

Living cells communicate information about physiological conditions by producing signaling molecules in a specific timed manner. Different conditions can result in the same total amount of a signaling molecule, differing only in the pattern…

Molecular Networks · Quantitative Biology 2018-10-09 Jackson O'Brien , Arvind Murugan

This work introduces the particle-intensity channel (PIC) as a model for molecular communication systems and characterizes the properties of the optimal input distribution and the capacity limits for this system. In the PIC, the transmitter…

Information Theory · Computer Science 2017-05-24 Nariman Farsad , Christopher Rose , Muriel Médard , Andrea Goldsmith

Physical thermodynamic and kinetic, chemical and biological reasoning restrict the spatial dimensions of living cells and confine them to between one and one hundred micrometers. Cells should necessarily be macroscopic, dissipative objects,…

Biological Physics · Physics 2017-05-12 Edward Bormashenko , Alexander Voronel

We investigate theoretically the efficiency of deep-space optical communication in the presence of background noise. With decreasing average signal power spectral density, a scaling gap opens up between optimized simple-decoded pulse…

Quantum Physics · Physics 2018-02-20 Marcin Jarzyna , Wojciech Zwoliński , Michał Jachura , Konrad Banaszek

Living cells can enhance their fitness by anticipating environmental change. We study how accurately linear signaling networks in cells can predict future signals. We find that maximal predictive power results from a combination of…

Molecular Networks · Quantitative Biology 2016-01-20 Nils B. Becker , Andrew Mugler , Pieter Rein ten Wolde

In this paper we show how inter-cellular molecular communication may change the overall levels of photosynthesis in plants. Individual plant cells respond to external stimuli, such as illumination levels, to regulate their photosynthetic…

Molecular Networks · Quantitative Biology 2021-03-30 Hamdan Awan , Raviraj S. Adve , Nigel Wallbridge , Carrol Plummer , Andrew W. Eckford

How would a cellular network designed for maximal energy efficiency look like? To answer this fundamental question, tools from stochastic geometry are used in this paper to model future cellular networks and obtain a new lower bound on the…

Information Theory · Computer Science 2016-04-06 Emil Björnson , Luca Sanguinetti , Marios Kountouris

Molecular Communication (MC) is an emerging field of research focused on understanding how cells in the human body communicate and exploring potential medical applications. In theoretical analysis, the goal is to investigate cellular…

Information Theory · Computer Science 2025-12-19 Wafa Labidi , Vida Gholamian , Yaning Zhao , Christian Deppe , Holger Boche

This paper focuses on molecular communication (MC) systems using two types of signaling molecules which may participate in a reversible bimolecular reaction in the channel. The motivation for studying these MC systems is that they can…

Information Theory · Computer Science 2019-07-25 Vahid Jamali , Nariman Farsad , Robert Schober , Andrea Goldsmith

During development, highly ordered structures emerge as cells collectively coordinate with each other. While recent advances have clarified how individual cells process and respond to external signals, understanding collective cellular…

Biological Physics · Physics 2026-02-05 Ashutosh Tripathi , Jörn Dunkel , Dominic J. Skinner

This paper studies optimal communication and coordination strategies in cyber-physical systems for both defender and attacker within a game-theoretic framework. We model the communication network of a cyber-physical system as a sensor…

Computer Science and Game Theory · Computer Science 2017-01-30 Emrah Akyol , Kenneth Rose , Tamer Basar , Cedric Langbort

It has been well-known since the pioneering work of Claude Shannon in the 1940s that a message transmitted with optimal efficiency over a channel of limited bandwidth is indistinguishable from random noise to a receiver who is unfamiliar…

Statistical Mechanics · Physics 2015-06-25 Michael Lachmann , M. E. J. Newman , Cristopher Moore