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To enhance the performance of large language models (LLMs) in biomedical natural language processing (BioNLP) by introducing a domain-specific instruction dataset and examining its impact when combined with multi-task learning principles.…

Pre-trained large language models demonstrate potential in extracting information from DNA sequences, yet adapting to a variety of tasks and data modalities remains a challenge. To address this, we propose DNAGPT, a generalized DNA…

This study aims to innovatively explore adaptive applications of large language models (LLM) in urban renewal. It also aims to improve its performance and text generation quality for knowledge question-answering (QA) tasks. Based on the…

Multilingual transfer ability, which reflects how well models fine-tuned on one source language can be applied to other languages, has been well studied in multilingual pre-trained models. However, the existence of such capability transfer…

While Genetic Improvement (GI) is a useful paradigm to improve functional and nonfunctional aspects of software, existing techniques tended to use the same set of mutation operators for differing objectives, due to the difficulty of writing…

Large Language Models (LLMs), such as ChatGPT, have taken the world by storm and have passed certain forms of the Turing test. However, LLMs are not limited to human language and analyze sequential data, such as DNA, protein, and gene…

AI tasks encompass a wide range of domains and fields. While numerous AI models have been designed for specific tasks and applications, they often require considerable human efforts in finding the right model architecture, optimization…

Large Language Models (LLMs) have revo lutionized natural language processing Natural Language Processing (NLP), with Chat Generative Pre-trained Transformer (ChatGPT) standing out as a notable exampledue to its advanced capabilities and…

Grammatical error correction aims to correct ungrammatical sentences automatically. Recently, some work has demonstrated the excellent capabilities of closed-source Large Language Models (LLMs, e.g., ChatGPT) in grammatical error…

With the productive evolution of large language models (LLMs) in the field of natural language processing (NLP), tons of effort has been made to effectively fine-tune common pre-trained LLMs to fulfill a variety of tasks in one or multiple…

Recently, ChatGPT and GPT-4 have emerged and gained immense global attention due to their unparalleled performance in language processing. Despite demonstrating impressive capability in various open-domain tasks, their adequacy in highly…

Large Language Models (LLMs), such as ChatGPT and GPT-4, have dramatically transformed natural language processing research and shown promising strides towards Artificial General Intelligence (AGI). Nonetheless, the high costs associated…

Objective To solve major clinical natural language processing (NLP) tasks using a unified text-to-text learning architecture based on a generative large language model (LLM) via prompt tuning. Methods We formulated 7 key clinical NLP tasks…

In 2022, with the release of ChatGPT, large-scale language models gained widespread attention. ChatGPT not only surpassed previous models in terms of parameters and the scale of its pretraining corpus but also achieved revolutionary…

Large Language Models (LLMs) such as GPT-4 have demonstrated their ability to understand natural language and generate complex code snippets. This paper introduces a novel Large Language Model Evolutionary Algorithm (LLaMEA) framework,…

Large language models (LLMs) are having transformative impacts across a wide range of scientific fields, particularly in the biomedical sciences. Just as the goal of Natural Language Processing is to understand sequences of words, a major…

Large Language Models (LLMs) have demonstrated excellent performance in general language understanding, generation and other tasks. However, when fine-tuning for specific domain tasks, the general knowledge accumulated in the pre-training…

While Large Language Models (LLMs) have demonstrated exceptional multitasking abilities, fine-tuning these models on downstream, domain-specific datasets is often necessary to yield superior performance on test sets compared to their…

Large language models (LLMs) are widely applied in various natural language processing tasks such as question answering and machine translation. However, due to the lack of labeled data and the difficulty of manual annotation for…

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…