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Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further…

Recently, deep neural networks have demonstrated excellent performances in recognizing the age and gender on human face images. However, these models were applied in a black-box manner with no information provided about which facial…

Machine Learning · Statistics 2017-08-28 Sebastian Lapuschkin , Alexander Binder , Klaus-Robert Müller , Wojciech Samek

Computer Aided Diagnosis has emerged as an indispensible technique for validating the opinion of radiologists in CT interpretation. This paper presents a deep 3D Convolutional Neural Network (CNN) architecture for automated CT scan-based…

Image and Video Processing · Electrical Eng. & Systems 2019-06-05 Sumita Mishra , Naresh Kumar Chaudhary , Pallavi Asthana , Anil Kumar

Objectives: Lung cancer poses a significant global health challenge, necessitating improved prognostic methods for personalized treatment. This study introduces a censor-aware semi-supervised learning (SSL) framework that integrates…

Medical Physics · Physics 2025-06-16 Arman Gorji , Ali Fathi Jouzdani , Nima Sanati , Ren Yuan , Arman Rahmim , Mohammad R. Salmanpour

Our knowledge of the organisation of the human brain at the population-level is yet to translate into power to predict functional differences at the individual-level, limiting clinical applications, and casting doubt on the generalisability…

Neurons and Cognition · Quantitative Biology 2024-04-04 James K Ruffle , Robert J Gray , Samia Mohinta , Guilherme Pombo , Chaitanya Kaul , Harpreet Hyare , Geraint Rees , Parashkev Nachev

Lung cancer is the leading cause of cancer-related mortality in adults worldwide. Screening high-risk individuals with annual low-dose CT (LDCT) can support earlier detection and reduce deaths, but widespread implementation may strain the…

Machine Learning · Computer Science 2025-12-30 Shaurya Gaur , Michel Vitale , Alessa Hering , Johan Kwisthout , Colin Jacobs , Lena Philipp , Fennie van der Graaf

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Deep learning models for pulmonary disease screening from Computed Tomography (CT) scans promise to alleviate the immense workload on radiologists. Still, their high computational cost, stemming from processing entire 3D volumes, remains a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-19 Qian Shao , Bang Du , Yixuan Wu , Zepeng Li , Qiyuan Chen , Qianqian Tang , Jian Wu , Jintai Chen , Hongxia Xu

We investigated the adaptation and performance of Masked Autoencoders (MAEs) with Vision Transformer (ViT) architectures for self-supervised representation learning on one-dimensional (1D) ultrasound signals. Although MAEs have demonstrated…

Machine Learning · Computer Science 2025-08-29 Immanuel Roßteutscher , Klaus S. Drese , Thorsten Uphues

Background: Existing clinical prediction models often represent patient data using features that ignore the semantic relationships between clinical concepts. This study integrates domain-specific semantic information by mapping the SNOMED…

Machine Learning · Computer Science 2025-08-21 Luis H. John , Jan A. Kors , Jenna M. Reps , Peter R. Rijnbeek , Egill A. Fridgeirsson

Abstract Background: Pulmonary function tests (PFTs) and computed tomography (CT) imaging are vital in diagnosing, managing, and monitoring lung diseases. A common issue in practice is the lack of access to recorded pulmonary functions…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Kaiwen Geng , Zhiyi Shi , Xiaoyan Zhao , Alaa Ali , Jing Wang , Joseph Leader , Jiantao Pu

Age estimation has attracted attention for its various medical applications. There are many studies on human age estimation from biomedical images. However, there is no research done on mammograms for age estimation, as far as we know. The…

Computer Vision and Pattern Recognition · Computer Science 2022-07-14 Charitha Dissanayake Lekamlage , Fabia Afzal , Erik Westerberg , Abbas Cheddad

3D structural Magnetic Resonance Imaging (MRI) brain scans are commonly acquired in clinical settings to monitor a wide range of neurological conditions, including neurodegenerative disorders and stroke. While deep learning models have…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Segmentation of lung tissue in computed tomography (CT) images is a precursor to most pulmonary image analysis applications. Semantic segmentation methods using deep learning have exhibited top-tier performance in recent years, however…

Image and Video Processing · Electrical Eng. & Systems 2023-04-27 Niloufar Delfan , Hamid Abrishami Moghaddam , Mohammadreza Modaresi , Kimia Afshari , Kasra Nezamabadi , Neda Pak , Omid Ghaemi , Mohamad Forouzanfar

Dental age is one of the most reliable methods to identify an individual's age. By using dental panoramic radiography (DPR) images, physicians and pathologists in forensic sciences try to establish the chronological age of individuals with…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Isa Atas , Cuneyt Ozdemir , Musa Atas , Yahya Dogan

Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as…

Computer Vision and Pattern Recognition · Computer Science 2018-07-19 Carlo Biffi , Ozan Oktay , Giacomo Tarroni , Wenjia Bai , Antonio De Marvao , Georgia Doumou , Martin Rajchl , Reem Bedair , Sanjay Prasad , Stuart Cook , Declan O'Regan , Daniel Rueckert

Inspired by recent findings that generative diffusion models learn semantically meaningful representations, we use them to discover the intrinsic hierarchical structure in biomedical 3D images using unsupervised segmentation. We show that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Nurislam Tursynbek , Marc Niethammer

Deep learning (DL) based predictive models from electronic health records (EHR) deliver impressive performance in many clinical tasks. Large training cohorts, however, are often required to achieve high accuracy, hindering the adoption of…

Computation and Language · Computer Science 2020-05-27 Laila Rasmy , Yang Xiang , Ziqian Xie , Cui Tao , Degui Zhi

Automated diagnosis from chest CT has improved considerably with deep learning, but models trained on skewed datasets tend to perform unevenly across patient demographics. However, the situation is worse than simple demographic bias. In…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Justin Li , Daniel Ding , Asmita Yuki Pritha , Aryana Hou , Xin Wang , Shu Hu

Deep Learning-based 2D/3D registration enables fast, robust, and accurate X-ray to CT image fusion when large annotated paired datasets are available for training. However, the need for paired CT volume and X-ray images with ground truth…

Image and Video Processing · Electrical Eng. & Systems 2022-10-17 Srikrishna Jaganathan , Maximilian Kukla , Jian Wang , Karthik Shetty , Andreas Maier