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The classical problem of indentation on an elastic substrate has found new applications in the field of the Atomic Force Microscopy. However, linearly elastic indentation models are not sufficiently accurate to predict the…

Soft Condensed Matter · Physics 2022-12-14 Yangkun Du , Peter Stewart , Nicholas A Hill , Huabing Yin , Raimondo Penta , Jakub Kory , Xiaoyu Luo , Raymond Ogden

Biological cells in soft materials can be modeled as anisotropic force contraction dipoles. The corresponding elastic interaction potentials are long-ranged ($\sim 1/r^3$ with distance $r$) and depend sensitively on elastic constants,…

Soft Condensed Matter · Physics 2009-11-07 U. S. Schwarz , S. A. Safran

We propose a one-dimensional, nonconvex elastic constitutive model with higher gradients that can predict spontaneous fracture at a critical load via a bifurcation analysis. It overcomes the problem of discontinuous deformations without…

Analysis of PDEs · Mathematics 2021-03-17 Phoebus Rosakis , Timothy J. Healey , Ugur Alyanak

Evaluating accessible conformational space is computationally expensive and thermal motions are partly neglected in computer models of molecular interactions. This produces error into the estimates of binding strength. We introduce a method…

Quantitative Methods · Quantitative Biology 2016-12-13 Riku Hakulinen , Santeri Puranen

One of the essential questions in the area of granular matter is, how to obtain macroscopic tensorial quantities like stress and strain from ``microscopic'' quantities like the contact forces in a granular assembly. Different averaging…

Statistical Mechanics · Physics 2007-05-23 Marc Lätzel , Stefan Luding , Hans J. Herrmann

The aim of this paper is to present and analyze a new direct method for solving the linear elasticity inverse problem. Given measurements of some displacement fields inside a medium, we show that a stable reconstruction of elastic…

Analysis of PDEs · Mathematics 2018-06-11 Habib Ammari , Elie Bretin , Pierre Millien , Laurent Seppecher

This study investigates the elastic response of a two-dimensional semi-infinite medium subjected to a moving surface load with a prescribed displacement profile. As a fundamental step, we derive analytical Green's functions for the…

Classical Physics · Physics 2026-04-23 Satoshi Takada , Yosuke Mori , Shintaro Hokada

Ultrasound elastography is the method to image the elasticity of compliant tissues due to a mechanical compression applied to it. In elastography, the local strain of explored tissue is estimated by analyzing the echo signals. This is…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Irteza Enan Kabir

Measurements with an atomic force microscope (AFM) offer a direct way to probe elastic properties of lipid bilayer membranes locally: provided the underlying stress-strain relation is known, material parameters such as surface tension or…

Soft Condensed Matter · Physics 2007-05-23 Davood Norouzi , Martin Michael Mueller , Markus Deserno

The constant interplay and information exchange between cells and their micro-environment are essential to their survival and ability to execute biological functions. To date, a few leading technologies such as traction force microscopy,…

Cell Behavior · Quantitative Biology 2023-06-29 Feng Xu , Shuxiang Zhang , Linjie Ma , Yong Hou , Jie Li , Andrej Denisenko , Zifu Li , Joachim Spatz , Jörg Wrachtrup , Qiang Wei , Zhiqin Chu

This work addresses the inverse identification of apparent elastic properties of random heterogeneous materials using machine learning based on artificial neural networks. The proposed neural network-based identification method requires the…

Machine Learning · Computer Science 2021-02-12 Florent Pled , Christophe Desceliers , Tianyu Zhang

The so-called indentation stiffness tomography technique for detecting the interior mechanical properties of an elastic sample with an inhomogeneity is analyzed in the framework of the asymptotic modeling approach under the assumption of…

Analysis of PDEs · Mathematics 2013-11-22 Ivan Argatov

Understanding cellular response to mechanical forces is immensely important for a plethora of biological processes. Focal adhesions are multi-molecular protein assemblies that connect the cell to the extracellular matrix and play a pivotal…

Biological Physics · Physics 2019-10-25 Rumi De

We study interactions between biological cells that apply anisotropic active mechanical forces on an elastic substrate. We model the cells as thin discs that along their perimeters apply radial, but angle-dependent forces on the substrate.…

Soft Condensed Matter · Physics 2019-03-28 Roman Golkov , Yair Shokef

Wrinkling of an inextensible elastic lining of an inner-lined tube under imposed pressure is considered. A simple equation modeling the elastic properties of the lining, the pressure, and the soft-substrate forces is derived. This equation…

Soft Condensed Matter · Physics 2022-01-20 Benjamin Foster , Nicolás Verschueren , Edgar Knobloch , Leonardo Gordillo

A high sensitivity force sensor based on dielectric microspheres in vacuum, optically trapped by a single, upward-propagating laser beam, is described. Off-axis parabolic mirrors are used both to focus the 1064~nm trapping beam and to…

Instrumentation and Detectors · Physics 2020-09-10 Akio Kawasaki , Alexander Fieguth , Nadav Priel , Charles P. Blakemore , Denzal Martin , Giorgio Gratta

To simulate a macroscopic system from a simulation cell, a direct summation of the elastic fields produced by periodic images can be used. If the cell contains a non-zero elastic dipole component, the sum is known to be conditionally…

Computational Physics · Physics 2019-02-18 Thomas Jourdan

The shapes of epithelial tissues result from a complex interplay of contractile forces in the cytoskeleta of the cells in the tissue, and adhesion forces between them. A host of discrete, cell-based models describe these forces by assigning…

Soft Condensed Matter · Physics 2019-02-27 Pierra A. Haas , Raymond E. Goldstein

Two-dimensional (2D) mechanical models of confluent tissues have related the mechanical state of a monolayer of cells to the average perimeter length of the cell cross sections, predicting floppiness or rigidity of the material. For the…

Soft Condensed Matter · Physics 2025-01-30 Jairo M. Rojas , Mayisha Z. Nakib , Vivian W. Tang , William M. Brieher , Sascha Hilgenfeldt

Accurately predicting friction in sliding interfaces that contain third body wear particles is critical for engineering applications such as sliding movement in pistons, bearings, or metal forming. We present a hierarchical multiscale…