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We present Bayesian Diffusion Models (BDM), a prediction algorithm that performs effective Bayesian inference by tightly coupling the top-down (prior) information with the bottom-up (data-driven) procedure via joint diffusion processes. We…

Computer Vision and Pattern Recognition · Computer Science 2024-04-23 Haiyang Xu , Yu Lei , Zeyuan Chen , Xiang Zhang , Yue Zhao , Yilin Wang , Zhuowen Tu

Diffusion models have been increasingly used as strong generative priors for solving inverse problems such as super-resolution in medical imaging. However, these approaches typically utilize a diffusion prior trained at a single scale,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-02 Darshan Thaker , Mahmoud Mostapha , Radu Miron , Shihan Qiu , Mariappan Nadar

Light microscopy is a widespread and inexpensive imaging technique facilitating biomedical discovery and diagnostics. However, light diffraction barrier and imperfections in optics limit the level of detail of the acquired images. The…

Quantitative Methods · Quantitative Biology 2026-03-24 Rui Li , Gabriel della Maggiora , Vardan Andriasyan , Anthony Petkidis , Artsemi Yushkevich , Mikhail Kudryashev , Artur Yakimovich

Diffusion models have recently achieved success in solving Bayesian inverse problems with learned data priors. Current methods build on top of the diffusion sampling process, where each denoising step makes small modifications to samples…

Machine Learning · Computer Science 2025-08-19 Bingliang Zhang , Wenda Chu , Julius Berner , Chenlin Meng , Anima Anandkumar , Yang Song

We provide a framework for solving inverse problems with diffusion models learned from linearly corrupted data. Firstly, we extend the Ambient Diffusion framework to enable training directly from measurements corrupted in the Fourier…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Asad Aali , Giannis Daras , Brett Levac , Sidharth Kumar , Alexandros G. Dimakis , Jonathan I. Tamir

Solving inverse problems with the reverse process of a diffusion model represents an appealing avenue to produce highly realistic, yet diverse solutions from incomplete and possibly noisy measurements, ultimately enabling uncertainty…

Geophysics · Physics 2025-01-10 Matteo Ravasi

Diffusion models have established new state of the art in a multitude of computer vision tasks, including image restoration. Diffusion-based inverse problem solvers generate reconstructions of exceptional visual quality from heavily…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Zalan Fabian , Berk Tinaz , Mahdi Soltanolkotabi

Diffusion models have emerged as a powerful foundation model for visual generations. With an appropriate sampling process, it can effectively serve as a generative prior for solving general inverse problems. Current posterior sampling-based…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Shijie Zhou , Huaisheng Zhu , Rohan Sharma , Jiayi Chen , Ruiyi Zhang , Kaiyi Ji , Changyou Chen

Recovering a signal from its degraded measurements is a long standing challenge in science and engineering. Recently, zero-shot diffusion based methods have been proposed for such inverse problems, offering a posterior sampling based…

Machine Learning · Computer Science 2026-05-19 Roi Benita , Michael Elad , Joseph Keshet

While supervised stereo matching and monocular depth estimation have advanced significantly with learning-based algorithms, self-supervised methods using stereo images as supervision signals have received relatively less focus and require…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Zihua Liu , Yizhou Li , Songyan Zhang , Masatoshi Okutomi

Diffusion models have demonstrated remarkable efficacy in generating high-quality samples. Existing diffusion-based image restoration algorithms exploit pre-trained diffusion models to leverage data priors, yet they still preserve elements…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Hongjie Wu , Linchao He , Mingqin Zhang , Dongdong Chen , Kunming Luo , Mengting Luo , Ji-Zhe Zhou , Hu Chen , Jiancheng Lv

Recent studies demonstrate that diffusion models can serve as a strong prior for solving inverse problems. A prominent example is Diffusion Posterior Sampling (DPS), which approximates the posterior distribution of data given the measure…

Machine Learning · Statistics 2024-09-16 Yaxuan Zhu , Zehao Dou , Haoxin Zheng , Yasi Zhang , Ying Nian Wu , Ruiqi Gao

With the rapid development of diffusion models and flow-based generative models, there has been a surge of interests in solving noisy linear inverse problems, e.g., super-resolution, deblurring, denoising, colorization, etc, with generative…

Machine Learning · Computer Science 2024-10-22 Xiangming Meng , Yoshiyuki Kabashima

We introduce a deep generative framework for high-dimensional Bayesian inference that enables efficient posterior sampling. As telescopes and simulations rapidly expand the volume and resolution of astrophysical data, fast simulation-based…

Instrumentation and Methods for Astrophysics · Physics 2026-03-06 Hadi Sotoudeh , Pablo Lemos , Laurence Perreault-Levasseur

While diffusion priors generate high-quality posterior samples across many inverse problems, they are often trained on limited training sets or purely simulated data, thus inheriting the errors and biases of these underlying sources.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Frederic Wang , Katherine L. Bouman

In diverse microscopy modalities, sensors measure only real-valued intensities. Additionally, the sensor readouts are affected by Poissonian-distributed photon noise. Traditional restoration algorithms typically aim to minimize the mean…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Nadav Torem , Roi Ronen , Yoav Y. Schechner , Michael Elad

We present the first framework to solve linear inverse problems leveraging pre-trained latent diffusion models. Previously proposed algorithms (such as DPS and DDRM) only apply to pixel-space diffusion models. We theoretically analyze our…

Machine Learning · Computer Science 2023-07-04 Litu Rout , Negin Raoof , Giannis Daras , Constantine Caramanis , Alexandros G. Dimakis , Sanjay Shakkottai

We present a new Bayesian methodology to learn the unknown material density of a given sample by inverting its two-dimensional images that are taken with a Scanning Electron Microscope. An image results from a sequence of projections of the…

Applications · Statistics 2014-03-06 Dalia Chakrabarty , Fabio Rigat , Nare Gabrielyan , Richard Beanland , Shashi Paul

Many interesting tasks in image restoration can be cast as linear inverse problems. A recent family of approaches for solving these problems uses stochastic algorithms that sample from the posterior distribution of natural images given the…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Bahjat Kawar , Michael Elad , Stefano Ermon , Jiaming Song

Optical astronomical images are strongly affected by the point spread function (PSF) of the optical system and the atmosphere (seeing) which blurs the observed image. The amount of blurring depends both on the observed band, and on the…

Instrumentation and Methods for Astrophysics · Physics 2023-08-31 Hong Wang , Sreevarsha Sreejith , Yuewei Lin , Nesar Ramachandra , Anže Slosar , Shinjae Yoo