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We study and develop a robust control framework for malware filtering and network security. We investigate the malware filtering problem by capturing the tradeoff between increased security on one hand and continued usability of the network…

Cryptography and Security · Computer Science 2009-11-13 Michael Bloem , Tansu Alpcan , Tamer Basar

We study an optimal control problem for a stochastic model of tumour growth with drug application. This model consists of three stochastic hyperbolic equations describing the evolution of tumour cells. It also includes two stochastic…

Optimization and Control · Mathematics 2024-08-30 Sakine Esmaili , M. R. Eslahchi , Delfim F. M. Torres

In this paper we design a novel class of online distributed optimization algorithms leveraging control theoretical techniques. We start by focusing on quadratic costs, and assuming to know an internal model of their variation. In this…

Optimization and Control · Mathematics 2026-01-21 Wouter J. A. van Weerelt , Nicola Bastianello

Complex social systems are composed of interconnected individuals whose interactions result in group behaviors. Optimal control of a real-world complex system has many applications, including road traffic management, epidemic prevention,…

Systems and Control · Computer Science 2019-05-08 Wen Dong , Bo Liu , Fan Yang

We consider an optimal control problem for a non-autonomous model of ODEs that describes the evolution of the number of customers in some firm. Namely we study the best marketing strategy. Considering a $L^2$ cost functional, we establish…

Optimization and Control · Mathematics 2018-02-16 S. Rosa , P. Rebelo , C. M. Silva , H. Alves , P. G. Carvalho

Mathematical theory of the quantum systems control is based on some ideas of the optimal control theory. These ideas are developed here as applied to these systems. The results obtained meet the deficiencies in the basis and algorithms of…

Quantum Physics · Physics 2008-05-22 V. F. Krotov

We propose a general framework for studying optimal impulse control problem in the presence of uncertainty on the parameters. Given a prior on the distribution of the unknown parameters, we explain how it should evolve according to the…

Probability · Mathematics 2017-12-06 N. Baradel , B. Bouchard , Ngoc Minh Dang

This paper is concerned with a constrained stochastic linear-quadratic optimal control problem, in which the terminal state is fixed and the initial state is constrained to lie in a stochastic linear manifold. The controllability of…

Optimization and Control · Mathematics 2019-06-11 Xiuchun Bi , Jingrui Sun , Jie Xiong

While the use of combination therapy is increasing in prevalence for cancer treatment, it is often difficult to predict the exact interactions between different treatment forms, and their synergistic/antagonistic effects on patient health…

Optimization and Control · Mathematics 2021-01-29 Jayanth Pratap

Modelling epidemics via classical population-based models suffers from shortcomings that so-called individual-based models are able to overcome, as they are able to take heterogeneity features into account, such as super-spreaders, and…

Optimization and Control · Mathematics 2022-05-16 C. Courtès , E. Franck , K. Lutz , L. Navoret , Y. Privat

This paper presents and discusses a mathematical model inspired by control theory to derive optimal public policies for minimizing costs associated with the reduction and control of criminal activity in a population. Specifically, we…

Systems and Control · Electrical Eng. & Systems 2026-05-25 Mariana Álvarez , Alexander Alegría , Andrés Rivera , Sebastián Pedersen

In this paper, we address an optimal distributed control problem for a non-local model of phase-field type, describing the evolution of tumour cells in presence of a nutrient. The model couples a non-local and viscous Cahn-Hilliard equation…

Analysis of PDEs · Mathematics 2023-10-25 Matteo Fornoni

Tuberculosis remains a significant global health challenge, with millions of new cases reported annually. Recent studies suggest that expanding the accessibility of TB intervention programs can lead to a substantial decrease in both TB…

Necessary optimality conditions and numerical methods for solving an optimal control problem for a linear continuous-time dynanical system with controlled coefficients and quadratic goal functional are discussed.

Optimization and Control · Mathematics 2010-04-20 Olga V. Baturina , Alexander V. Bulatov , Vadim F. Krotov

The appearance of a new dangerous and contagious disease requires the development of a drug therapy faster than what is foreseen by usual mechanisms. Many drug therapy developments consist in investigating through different clinical trials…

Quantitative Methods · Quantitative Biology 2020-03-31 Ezequiel Alvarez , Federico Lamagna , Manuel Szewc

Discrete-time robust optimal control problems generally take a min-max structure over continuous variable spaces, which can be difficult to solve in practice. In this paper, we extend the class of such problems that can be solved through a…

Optimization and Control · Mathematics 2024-04-30 Jad Wehbeh , Eric C. Kerrigan

It is recognized that social heterogeneities in terms of the contact distribution have a strong influence on the spread of infectious diseases. Nevertheless, few data are available on the group composition of social contacts, and their…

Optimization and Control · Mathematics 2023-06-09 Jonathan Franceschi , Andrea Medaglia , Mattia Zanella

This paper is devoted to the study of the dynamic optimization of several controlled crowd motion models in the general planar settings, which is an application of a class of optimal control problems involving a general nonconvex sweeping…

Optimization and Control · Mathematics 2025-01-20 Tan H. Cao , Nilson Chapagain , Haejoon Lee , Phung Ngoc Thi , Nguyen Nang Thieu

We apply optimal control theory to a tuberculosis model given by a system of ordinary differential equations. Optimal control strategies are proposed to minimize the cost of interventions. Numerical simulations are given using data from…

Optimization and Control · Mathematics 2012-07-23 Cristiana J. Silva , Delfim F. M. Torres

This paper investigates an optimal control problem associated with a two-dimensional multi-species Cahn-Hilliard-Keller-Segel tumor growth model, which incorporates complex biological processes such as species diffusion, chemotaxis,…

Analysis of PDEs · Mathematics 2024-07-26 Pierluigi Colli , Gianni Gilardi , Andrea Signori , Jürgen Sprekels