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We construct a zig-zag process targeting a posterior distribution defined on a hybrid state space consisting of both discrete and continuous variables. The construction does not require any assumptions on the structure among discrete…

Computation · Statistics 2024-01-30 Jere Koskela

Suffering from the semantic insufficiency and domain-shift problems, most of existing state-of-the-art methods fail to achieve satisfactory results for Zero-Shot Learning (ZSL). In order to alleviate these problems, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-02-24 Hongxin Xiang , Cheng Xie , Ting Zeng , Yun Yang

A new two-parameter discrete distribution, namely the PoiG distribution is derived by the convolution of a Poisson variate and an independently distributed geometric random variable. This distribution generalizes both the Poisson and…

Methodology · Statistics 2024-07-11 Anupama Nandi , Subrata Chakraborty , Aniket Biswas

Model-X knockoffs allows analysts to perform feature selection using almost any machine learning algorithm while still provably controlling the expected proportion of false discoveries. To apply model-X knockoffs, one must construct…

Methodology · Statistics 2021-06-30 Asher Spector , Lucas Janson

This paper develops a method based on model-X knockoffs to find conditional associations that are consistent across diverse environments, controlling the false discovery rate. The motivation for this problem is that large data sets may…

Methodology · Statistics 2021-06-09 Shuangning Li , Matteo Sesia , Yaniv Romano , Emmanuel Candès , Chiara Sabatti

We describe a new algorithm and R package for peak detection in genomic data sets using constrained changepoint algorithms. These detect changes from background to peak regions by imposing the constraint that the mean should alternately…

Computation · Statistics 2018-10-02 Toby Dylan Hocking , Guillem Rigaill , Paul Fearnhead , Guillaume Bourque

Vine copulas are a flexible tool for high-dimensional dependence modeling. In this article, we discuss the generation of approximate model-X knockoffs with vine copulas. It is shown how Gaussian knockoffs can be generalized to Gaussian…

Methodology · Statistics 2022-10-21 Malte S. Kurz

Motivation: Histone modification constitutes a basic mechanism for the genetic regulation of gene expression. In early 2000s, a powerful technique has emerged that couples chromatin immunoprecipitation with high-throughput sequencing…

Quantitative Methods · Quantitative Biology 2020-12-16 Arnaud Liehrmann , Guillem Rigaill , Toby Dylan Hocking

Testing composite null hypotheses arises in various applications, such as mediation and replicability analyses. The problem becomes more challenging in high-throughput experiments where tens of thousands of features are examined…

Methodology · Statistics 2025-04-29 Pengfei Lyu , Xianyang Zhang , Hongyuan Cao

Support points summarize a large dataset through a smaller set of representative points that can be used for data operations, such as Monte Carlo integration, without requiring access to the full dataset. In this sense, support points offer…

Machine Learning · Statistics 2025-09-01 Peiqi Zhao , Carlos E. Rodríguez , Ramsés H. Mena , Stephen G. Walker

We propose a Bayesian procedure for simultaneous variable and covariance selection using continuous spike-and-slab priors in multivariate linear regression models where q possibly correlated responses are regressed onto p predictors. Rather…

Methodology · Statistics 2019-03-29 Sameer K. Deshpande , Veronika Rockova , Edward I. George

Large annotated datasets are crucial for the success of deep neural networks, but labeling data can be prohibitively expensive in domains such as medical imaging. This work tackles the subset selection problem: selecting a small set of the…

Machine Learning · Computer Science 2025-09-29 Noga Bar , Raja Giryes

Single-cell transcriptomic data approximates the abundance of proteins at a high resolution, but its noisiness necessitates transformation by a pipeline of methods before analysis and inference. In the absence of robust validation of these…

Applications · Statistics 2026-04-13 Toby Kettlewell , Yiyi Cheng , Thomas D. Otto , Vincent Macaulay , Mayetri Gupta

Quantum random number generators (QRNGs) harness quantum mechanical unpredictability to produce true randomness, which is crucial for cryptography and secure communications. Among various QRNGs, source-independent QRNGs (SI-QRNGs) relax the…

Quantum Physics · Physics 2024-11-25 Hongyi Zhou

Suppose there is a large collection of items, each with an associated cost and an inherent utility that is revealed only once we commit to selecting it. Given a budget on the cumulative cost of the selected items, how can we pick a subset…

Machine Learning · Computer Science 2015-06-08 Hastagiri P. Vanchinathan , Andreas Marfurt , Charles-Antoine Robelin , Donald Kossmann , Andreas Krause

Text-to-image generation models have made significant progress in producing high-quality images from textual descriptions, yet they continue to struggle with maintaining subject consistency across multiple images, a fundamental requirement…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Mingxiao Li , Mang Ning , Marie-Francine Moens

Combined inference for heterogeneous high-dimensional data is critical in modern biology, where clinical and various kinds of molecular data may be available from a single study. Classical genetic association studies regress a single…

Applications · Statistics 2017-03-22 Hélène Ruffieux , Anthony C. Davison , Jörg Hager , Irina Irincheeva

Gaussian graphical models emerge in a wide range of fields. They model the statistical relationships between variables as a graph, where an edge between two variables indicates conditional dependence. Unfortunately, well-established…

Machine Learning · Statistics 2024-01-19 Taulant Koka , Jasin Machkour , Michael Muma

Genomics biobanks are information treasure troves with thousands of phenotypes (e.g., diseases, traits) and millions of single nucleotide polymorphisms (SNPs). The development of methodologies that provide reproducible discoveries is…

Methodology · Statistics 2024-10-08 Jasin Machkour , Michael Muma , Daniel P. Palomar

Instance-wise feature selection and ranking methods can achieve a good selection of task-friendly features for each sample in the context of neural networks. However, existing approaches that assume feature subsets to be independent are…

Machine Learning · Computer Science 2023-08-02 Hanyu Peng , Guanhua Fang , Ping Li
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