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Large language models (LLMs) can generate or synthesize clinical text for a wide range of applications, from improving clinical documentation to augmenting clinical text analytics. Yet evaluations typically focus on a narrow aspect -- such…

Computation and Language · Computer Science 2026-05-19 Jinghui Liu , Sarvesh Soni , Anthony Nguyen

Large pre-trained language models (LMs) have been widely adopted in biomedical and clinical domains, introducing many powerful LMs such as bio-lm and BioELECTRA. However, the applicability of these methods to real clinical use cases is…

Computation and Language · Computer Science 2022-11-16 Samuel Cahyawijaya , Bryan Wilie , Holy Lovenia , Huan Zhong , MingQian Zhong , Yuk-Yu Nancy Ip , Pascale Fung

This study evaluates the linguistic and clinical suitability of synthetic electronic health records in mental health. First, we describe the rationale and the methodology for creating the synthetic corpus. Second, we examine expressions of…

Computation and Language · Computer Science 2026-02-05 Serge Sharoff , John Baker , David Francis Hunt , Alan Simpson

The increasing volume and complexity of clinical documentation in Electronic Medical Records systems pose significant challenges for clinical coders, who must mentally process and summarise vast amounts of clinical text to extract essential…

Computation and Language · Computer Science 2024-09-25 Bokang Bi , Leibo Liu , Sanja Lujic , Louisa Jorm , Oscar Perez-Concha

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Synthetic Electronic Health Records (EHRs) offer a valuable opportunity to create privacy preserving and harmonized structured data, supporting numerous applications in healthcare. Key benefits of synthetic data include precise control over…

Computation and Language · Computer Science 2025-04-28 Yihan Lin , Zhirong Bella Yu , Simon Lee

Large Language Models (LLMs) have demonstrated remarkable proficiency in automated text annotation within natural language processing. However, their deployment in clinical settings is severely constrained by strict privacy regulations and…

Large language models (LLMs) have performed well across various clinical natural language processing tasks, despite not being directly trained on electronic health record (EHR) data. In this work, we examine how popular open-source LLMs…

Computation and Language · Computer Science 2025-05-26 Furong Jia , David Sontag , Monica Agrawal

Europe's healthcare systems require enhanced interoperability and digitalization, driving a demand for innovative solutions to process legacy clinical data. This paper presents the results of our project, which aims to leverage Large…

Computation and Language · Computer Science 2025-07-09 Aynur Guluzade , Naguib Heiba , Zeyd Boukhers , Florim Hamiti , Jahid Hasan Polash , Yehya Mohamad , Carlos A Velasco

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Large Language Models (LLMs) have shown strong promise for mining Electronic Health Records (EHRs) by reasoning over longitudinal clinical information to capture context-rich patient trajectories. However, leveraging LLMs for structured…

Computation and Language · Computer Science 2026-04-21 Arya Hadizadeh Moghaddam , Drew Ross , Mohsen Nayebi Kerdabadi , Dongjie Wang , Zijun Yao

Recently published work on rephrasing natural text data for pre-training LLMs has shown promising results when combining the original dataset with the synthetically rephrased data. We build upon previous work by replicating existing results…

Although recent advances in scaling large language models (LLMs) have resulted in improvements on many NLP tasks, it remains unclear whether these models trained primarily with general web text are the right tool in highly specialized,…

The advent of large language models (LLMs) has opened new avenues for analyzing complex, unstructured data, particularly within the medical domain. Electronic Health Records (EHRs) contain a wealth of information in various formats,…

Information Retrieval · Computer Science 2025-06-10 Wu Hao Ran , Xi Xi , Furong Li , Jingyi Lu , Jian Jiang , Hui Huang , Yuzhuan Zhang , Shi Li

Despite being a unique source of information on patients' status and disease progression, clinical notes are characterized by high levels of duplication and information redundancy. In general domain text, it has been shown that…

Computation and Language · Computer Science 2023-12-18 Isotta Landi , Eugenia Alleva , Alissa A. Valentine , Lauren A. Lepow , Alexander W. Charney

Electronic Health Records (EHRs) provide crucial information for clinical decision-making. However, their high-dimensionality, heterogeneity, and sparsity make clinical prediction challenging. Large Language Models (LLMs) allowed progress…

Computation and Language · Computer Science 2026-01-28 Jesus Lovon-Melgarejo , Jose G. Moreno , Christine Damase-Michel , Lynda Tamine

Many sensitive domains -- such as the clinical domain -- lack widely available datasets due to privacy risks. The increasing generative capabilities of large language models (LLMs) have made synthetic datasets a viable path forward. In this…

Computation and Language · Computer Science 2025-06-03 Thomas Vakili , Aron Henriksson , Hercules Dalianis

Clinical language models have achieved strong performance on downstream tasks by pretraining on domain specific corpora such as discharge summaries and medical notes. However, most approaches treat the electronic health record as a static…

Computation and Language · Computer Science 2025-04-28 Tatsunori Tanaka , Fi Zheng , Kai Sato , Zhifeng Li , Yuanyun Zhang , Shi Li

Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

Artificial Intelligence · Computer Science 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani
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