English
Related papers

Related papers: Tip-Enhanced Sum Frequency Generation for Molecula…

200 papers

A common starting point for drug design is to find small chemical groups or "fragments" that form interactions with distinct subregions in a protein binding pocket. The subsequent challenge is to assemble these fragments into a molecule…

Quantitative Methods · Quantitative Biology 2025-05-29 Rohan V. Koodli , Alexander S. Powers , Ayush Pandit , Chiho Im , Ron O. Dror

Surface-enhanced Raman spectroscopy is a powerful and versatile sensing method with a detection limit down to the single molecule level. In this article, we demonstrate how topology optimization (TopOpt) can be used for designing surface…

Mesoscale and Nanoscale Physics · Physics 2021-08-25 Ying Pan , Rasmus E. Christiansen , Jerome Michon , Juejun Hu , Steven G. Johnson

Photometric and astrometric monitoring of directly imaged exoplanets will deliver unique insights into their rotational periods, the distribution of cloud structures, weather, and orbital parameters. As the host star is occulted by the…

Instrumentation and Methods for Astrophysics · Physics 2020-07-01 Steven P. Bos

Scattering scanning near-field optical microscopy (s-SNOM) is a powerful technique for mid-infrared spectroscopy at nanometer length scales. By investigating objects in aqueous environments through ultrathin membranes, s-SNOM has recently…

We investigate systematically the bulk and surface electronic structure of the candidate nodal-line semimetal CaAgAs by angle resolved photoemission spectroscopy and density functional calculations. We observed a metallic, linear,…

Sensitivity of gravitational-wave detectors is limited in the high-frequency band by quantum shot noise and eventually limited by the optical loss in signal recycling cavity. This limit is the main obstacle on the way to detect…

General Relativity and Quantum Cosmology · Physics 2022-01-05 Teng Zhang , Denis Martynov , Stefan Danilishin , Haixing Miao

Spotforming is a target-speaker extraction technique that uses multiple microphone arrays. This method applies beamforming (BF) to each microphone array, and the common components among the BF outputs are estimated as the target source.…

Sound · Computer Science 2024-07-15 Shoma Ayano , Li Li , Shogo Seki , Daichi Kitamura

Scattering scanning near-field optical microscopy (s-SNOM) is a promising technique for overcoming Abbe diffraction limit and substantially enhancing the spatial resolution in spectroscopic imaging. The s-SNOM works by exposing an atomic…

Quantum Physics · Physics 2024-03-22 Soheil Khajavi , Zahra Shaterzadeh-Yazdi , Ali Eghrari , Mohammad Neshat

By projecting onto complex optical mode profiles, it is possible to estimate arbitrarily small separations between objects with quantum-limited precision, free of uncertainty arising from overlapping intensity profiles. Here we extend these…

Nonlinear metasurfaces offer new paradigm for boosting optical effect beyond limitations of conventional materials. In this work, we present an alternative way to produce pronounced third-harmonic generation (THG) based on nonlinear field…

Spike camera, a type of neuromorphic sensor with high-temporal resolution, shows great promise for high-speed visual tasks. Unlike traditional cameras, spike camera continuously accumulates photons and fires asynchronous spike streams. Due…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Liwen Hu , Yang Li , Mianzhi Liu , Yijia Guo , Shenghao Xie , Ziluo Ding , Tiejun Huang , Lei Ma

High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use…

Image and Video Processing · Electrical Eng. & Systems 2019-03-28 Li-Hao Yeh , Shwetadwip Chowdhury , Laura Waller

In recent years, computational Time-of-Flight (ToF) imaging has emerged as an exciting and a novel imaging modality that offers new and powerful interpretations of natural scenes, with applications extending to 3D, light-in-flight, and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Ruiming Guo , Ayush Bhandari

The paper reports on experimental observation of sub-terahertz sound wave generation and detection by a long Josephson junction. This effect was discovered at spectral measurements of sub-terahertz electromagnetic emission from a flux-flow…

Superconductivity · Physics 2015-06-18 Valery P. Koshelets

Electron-spin resonance carried out with scanning tunneling microscopes (ESR-STM) is a recently developed experimental technique that is attracting enormous interest on account of its potential to carry out single-spin on-surface resonance…

Mesoscale and Nanoscale Physics · Physics 2023-04-19 Santiago A. Rodríguez , Sergio S. Gómez , Joaquín Fernández-Rossier , Alejandro Ferrón

An apporach for the sensing of small amounts of chemical and biochemical material is presented. A frequency selective surface (FSS) made from asymmetric split ring resonators (aDSR) is excited with free space radiation. Due to interference…

Applied Physics · Physics 2021-04-13 Christian Debus , Peter Haring Bolívar

Tip-enhanced Raman scattering (TERS) has emerged as a powerful tool to obtain subnanometer spatial resolution fingerprints of atomic motion. Theoretical calculations that can simulate the Raman scattering process and provide an unambiguous…

Chemical Physics · Physics 2023-08-10 Y. Litman , F. P. Bonafé , A. Akkoush , H. Appel , M. Rossi

Ultrafast science and technology have brought in burgeoning opportunities to optical metrology, strong-field physics, non-equilibrium physics, etc., through light-matter interaction due to ever-advancing temporal resolution and peak power…

Optics · Physics 2022-11-28 Yi Chan , Fu Deng , Jingdi Zhang

Molecular conformation generation poses a significant challenge in the field of computational chemistry. Recently, Diffusion Probabilistic Models (DPMs) and Score-Based Generative Models (SGMs) are effectively used due to their capacity for…

Machine Learning · Computer Science 2024-09-24 Sijia Wang , Chen Wang , Zhenhao Zhao , Jiqiang Zhang , Weiran Cai