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Precise and efficient automated identification of Gastrointestinal (GI) tract diseases can help doctors treat more patients and improve the rate of disease detection and identification. Currently, automatic analysis of diseases in the GI…

Recent studies have demonstrated the diagnostic and prognostic values of global glomerulosclerosis (GGS) in IgA nephropathy, aging, and end-stage renal disease. However, the fine-grained quantitative analysis of multiple GGS subtypes (e.g.,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Yuzhe Lu , Haichun Yang , Zuhayr Asad , Zheyu Zhu , Tianyuan Yao , Jiachen Xu , Agnes B. Fogo , Yuankai Huo

The Gleason grading system using histological images is the most powerful diagnostic and prognostic predictor of prostate cancer. The current standard inspection is evaluating Gleason H&E-stained histopathology images by pathologists.…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Haotian Xie , Yong Zhang , Jun Wang , Jingjing Zhang , Yifan Ma , Zhaogang Yang

High-throughput image analysis in the biomedical domain has gained significant attention in recent years, driving advancements in drug discovery, disease prediction, and personalized medicine. Organoids, specifically, are an active area of…

In recent years, the use of deep learning (DL) methods, including convolutional neural networks (CNNs) and vision transformers (ViTs), has significantly advanced computational pathology, enhancing both diagnostic accuracy and efficiency.…

Quantum machine learning has emerged as a promising approach for medical image analysis, particularly in settings where compact models and expressive feature representations are desired. This paper presents a hybrid classical--quantum…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Shabnam Sodagari , Tommy Long

In this study, we built an end-to-end tumor-infiltrating lymphocytes (TILs) assessment pipeline within QuPath, demonstrating the potential of easily accessible tools to perform complex tasks in a fully automatic fashion. First, we trained a…

To achieve minimum DNA input and tumor purity requirements for next-generation sequencing (NGS), pathologists visually estimate macrodissection and slide count decisions. Misestimation may cause tissue waste and increased laboratory costs.…

Tuberculosis remains a critical global health issue, particularly in resource-limited and remote areas. Early detection is vital for treatment, yet the lack of skilled radiologists underscores the need for artificial intelligence…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Neel Patel , Alexander Wong , Ashkan Ebadi

The shortage of nephrologists and the growing public health concern over renal failure have spurred the demand for AI systems capable of autonomously detecting kidney abnormalities. Renal failure, marked by a gradual decline in kidney…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Tahmim Hossain , Faisal Sayed , Solehin Islam

In the burgeoning field of AI-driven image generation, the quest for precision and relevance in response to textual prompts remains paramount. This paper introduces GPTDrawer, an innovative pipeline that leverages the generative prowess of…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Kun Li , Xinwei Chen , Tianyou Song , Hansong Zhang , Wenzhe Zhang , Qing Shan

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

The interpretation of histopathology cases underlies many important diagnostic and treatment decisions in medicine. Notably, this process typically requires pathologists to integrate and summarize findings across multiple slides per case.…

Deep learning is a powerful tool for whole slide image (WSI) analysis. Typically, when performing supervised deep learning, a WSI is divided into small patches, trained and the outcomes are aggregated to estimate disease grade. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-05-20 Yi Zheng , Rushin H. Gindra , Emily J. Green , Eric J. Burks , Margrit Betke , Jennifer E. Beane , Vijaya B. Kolachalama

Accurate segmentation of glomerulus instances attains high clinical significance in the automated analysis of renal biopsies to aid in diagnosing and monitoring kidney disease. Analyzing real-world histopathology images often encompasses…

Cancer survival prediction from whole slide images (WSIs) is a challenging task in computational pathology due to the large size, irregular shape, and high granularity of the WSIs. These characteristics make it difficult to capture the full…

Image and Video Processing · Electrical Eng. & Systems 2025-03-05 Rustin Soraki , Huayu Wang , Joann G. Elmore , Linda Shapiro

Normally eosinophils are present in the gastrointestinal (GI) tract of healthy individuals. When the eosinophils increase beyond their usual amount in the GI tract, a patient gets varied symptoms. Clinicians find it difficult to diagnose…

Quantitative Methods · Quantitative Biology 2022-11-30 Harsh Shah , Thomas Jacob , Amruta Parulekar , Anjali Amarapurkar , Amit Sethi

Large-scale image data such as digital whole-slide histology images pose a challenging task at annotation software solutions. Today, a number of good solutions with varying scopes exist. For cell annotation, however, we find that many do…

Computer Vision and Pattern Recognition · Computer Science 2018-10-03 Marc Aubreville , Christof Bertram , Robert Klopfleisch , Andreas Maier

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He
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