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This paper deals with parameter estimation in pair hidden Markov models (pair-HMMs). We first provide a rigorous formalism for these models and discuss possible definitions of likelihoods. The model being biologically motivated, some…

Statistics Theory · Mathematics 2010-12-09 Ana Arribas-Gil , Elisabeth Gassiat , Catherine Matias

Many applications require that we learn the parameters of a model from data. EM is a method used to learn the parameters of probabilistic models for which the data for some of the variables in the models is either missing or hidden. There…

Machine Learning · Computer Science 2013-01-30 Luis E. Ortiz , Leslie Pack Kaelbling

The asymptotic variance of the maximum likelihood estimate is proved to decrease when the maximization is restricted to a subspace that contains the true parameter value. Maximum likelihood estimation allows a systematic fitting of…

Statistics Theory · Mathematics 2018-01-31 Marie Turčičová , Jan Mandel , Kryštof Eben

This paper presents some results on the maximum likelihood (ML) estimation from incomplete data. Finite sample properties of conditional observed information matrices are established. They possess positive definiteness and the same Loewner…

Methodology · Statistics 2022-07-26 Budhi Arta Surya

Item Response Theory (IRT) models have received growing interest in health science for analyzing latent constructs such as depression, anxiety, quality of life, or cognitive functioning from the information provided by each individual's…

Large language models (LLMs) have demonstrated exceptional performance across a wide range of natural language tasks. However, selecting the optimal LLM to respond to a user query often necessitates a delicate balance between performance…

Artificial Intelligence · Computer Science 2025-06-24 Wei Song , Zhenya Huang , Cheng Cheng , Weibo Gao , Bihan Xu , GuanHao Zhao , Fei Wang , Runze Wu

Optimum parameter estimation methods require knowledge of a parametric probability density that statistically describes the available observations. In this work we examine Bayesian and non-Bayesian parameter estimation problems under a…

Applications · Statistics 2022-02-01 George V. Moustakides

This paper considers an empirical likelihood inference for parameters defined by general estimating equations, when data are missing at random. The efficiency of existing estimators depends critically on correctly specifying the conditional…

Methodology · Statistics 2016-12-06 Tianqing Liu , Xiaohui Yuan , Zhaohai Li , Aiyi Liu

We consider fully row/column-correlated linear regression models and study several classical estimators (including minimum norm interpolators (GLS), ordinary least squares (LS), and ridge regressors). We show that \emph{Random Duality…

Machine Learning · Statistics 2024-06-14 Mihailo Stojnic

We present a general problem formulation for optimal parameter estimation based on quantized observations, with application to antenna array communication and processing (channel estimation, time-of-arrival (TOA) and direction-of-arrival…

Information Theory · Computer Science 2010-10-28 Amine Mezghani , Felix Antreich , Josef A. Nossek

We propose and study properties of maximum likelihood estimators in the class of conditional transformation models. Based on a suitable explicit parameterisation of the unconditional or conditional transformation function, we establish a…

Methodology · Statistics 2019-10-22 Torsten Hothorn , Lisa Möst , Peter Bühlmann

Models with multiple change points are used in many fields; however, the theoretical properties of maximum likelihood estimators of such models have received relatively little attention. The goal of this paper is to establish the asymptotic…

Statistics Theory · Mathematics 2011-02-28 Heping He , Thomas A. Severini

In this article, we construct empirical likelihood (EL)-weighted estimators of linear functionals of a probability measure in the presence of side information. Motivated by nuisance parameters in semiparametric models with possibly infinite…

Statistics Theory · Mathematics 2023-01-25 Shan Wang , Hanxiang Peng

This paper addresses the problem of learning the impulse responses characterizing forward models by means of a regularized kernel-based Prediction Error Method (PEM). The common approach to accomplish that is to approximate the system with…

Optimization and Control · Mathematics 2024-09-20 Giulio Fattore , Marco Peruzzo , Giacomo Sartori , Mattia Zorzi

Parameter estimation in ordinary differential equations, although applied and refined in various fields of the quantitative sciences, is still confronted with a variety of difficulties. One major challenge is finding the global optimum of a…

Quantitative Methods · Quantitative Biology 2013-02-11 Daniel Kaschek , Jens Timmer

Modeling item parameters as a function of item characteristics has a long history but has generally focused on models for item location. Explanatory item response models for item discrimination are available but rarely used. In this study,…

Methodology · Statistics 2025-06-24 Joshua B. Gilbert , Lijin Zhang , Esther Ulitzsch , Benjamin W. Domingue

We consider the problem of parameter estimation in a high-dimensional generalized linear model. Spectral methods obtained via the principal eigenvector of a suitable data-dependent matrix provide a simple yet surprisingly effective…

Statistics Theory · Mathematics 2025-07-11 Yihan Zhang , Hong Chang Ji , Ramji Venkataramanan , Marco Mondelli

The EM algorithm is a generic tool that offers maximum likelihood solutions when datasets are incomplete with data values missing at random or completely at random. At least for its simplest form, the algorithm can be rewritten in terms of…

Methodology · Statistics 2025-09-25 Daniel A. Griffith

A novel estimation approach for a general class of semi-parametric multivariate time series models is introduced where the conditional mean is modeled through parametric functions. The focus of the estimation is the conditional mean…

Methodology · Statistics 2025-07-21 Mirko Armillotta

This paper deals with parameter estimation from extreme measurements. While being a special case of parameter estimation from partial data, in scenarios where only one sample from a given set of K measurements can be extracted, choosing…

Signal Processing · Electrical Eng. & Systems 2018-09-25 Jonatan Ostrometzky , Hagit Messer