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Related papers: Linguistic Laws Meet Protein Sequences: A Comparat…

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Tokenization or segmentation is a wide concept that covers simple processes such as separating punctuation from words, or more sophisticated processes such as applying morphological knowledge. Neural Machine Translation (NMT) requires a…

Computation and Language · Computer Science 2019-06-12 Miguel Domingo , Mercedes Garcıa-Martınez , Alexandre Helle , Francisco Casacuberta , Manuel Herranz

Just as physicists strive to develop a TOE (theory of everything), which explains and unifies the physical laws of the universe, the life-scientist wishes to uncover the TOE as it relates to cellular systems. This can only be achieved with…

Quantitative Methods · Quantitative Biology 2009-11-04 Kyung Dae Ko , Yoojin Hong , Gaurav Bhardwaj , Teresa M. Killick , Damian B. van Rossum , Randen L. Patterson

Is there a foreign language describing protein sequences and structures simultaneously? Protein structures, represented by continuous 3D points, have long posed a challenge due to the contrasting modeling paradigms of discrete sequences. We…

Biomolecules · Quantitative Biology 2024-03-20 Zhangyang Gao , Cheng Tan , Jue Wang , Yufei Huang , Lirong Wu , Stan Z. Li

Neural sequence-to-sequence models provide a competitive approach to the task of mapping a question in natural language to an SQL query, also referred to as text-to-SQL generation. The Byte-Pair Encoding algorithm (BPE) has previously been…

Computation and Language · Computer Science 2019-11-19 Samuel Müller , Andreas Vlachos

Variation in language is ubiquitous and often systematically linked to regional, social, and contextual factors. Tokenizers split texts into smaller units and might behave differently for less common linguistic forms. This might affect…

Computation and Language · Computer Science 2025-07-08 Anna Wegmann , Dong Nguyen , David Jurgens

Adapting language models to new data distributions by simple finetuning is challenging. This is due to the rigidity of their subword tokenizers, which typically remain unchanged during adaptation. This inflexibility often leads to…

Computation and Language · Computer Science 2026-05-14 Abraham Toluwase Owodunni , Orevaoghene Ahia , Sachin Kumar

The size of the vocabulary is a central design choice in large pretrained language models, with respect to both performance and memory requirements. Typically, subword tokenization algorithms such as byte pair encoding and WordPiece are…

Computation and Language · Computer Science 2021-09-14 Antonis Maronikolakis , Philipp Dufter , Hinrich Schütze

Scientific Large Language Models (Sci-LLMs) have emerged as a promising frontier for accelerating biological discovery. However, these models face a fundamental challenge when processing raw biomolecular sequences: the tokenization dilemma.…

Most current popular subword tokenizers are trained based on word frequency statistics over a corpus, without considering information about co-occurrence or context. Nevertheless, the resulting vocabularies are used in language models'…

Computation and Language · Computer Science 2023-02-13 Shaked Yehezkel , Yuval Pinter

Discrete audio tokens derived from self-supervised learning models have gained widespread usage in speech generation. However, current practice of directly utilizing audio tokens poses challenges for sequence modeling due to the length of…

Sound · Computer Science 2024-01-17 Feiyu Shen , Yiwei Guo , Chenpeng Du , Xie Chen , Kai Yu

The paradigm of large language models in natural language processing (NLP) has also shown promise in modeling biological languages, including proteins, RNA, and DNA. Both the auto-regressive generation paradigm and evaluation metrics have…

Biomolecules · Quantitative Biology 2025-07-04 Ke Liu , Shuaike Shen , Hao Chen

Accurately annotating and controlling protein function from sequence data remains a major challenge, particularly within homologous families where annotated sequences are scarce and structural variation is minimal. We present a two-stage…

Quantitative Methods · Quantitative Biology 2025-07-22 Lorenzo Rosset , Martin Weigt , Francesco Zamponi

Past vocabulary learning techniques identify relevant vocabulary before training, relying on statistical and entropy-based assumptions that largely neglect the role of model training. Empirically, we observe that trained translation models…

Computation and Language · Computer Science 2025-04-02 Pin-Jie Lin , Ernie Chang , Yangyang Shi , Vikas Chandra

Prior research has demonstrated noticeable performance gains through the use of probabilistic tokenizations, an approach that involves employing multiple tokenizations of the same input string during the training phase of a language model.…

Computation and Language · Computer Science 2024-07-08 Ashutosh Sathe , Divyanshu Aggarwal , Sunayana Sitaram

Unsupervised Machine Learning techniques have been applied to Natural Language Processing tasks and surpasses the benchmarks such as GLUE with great success. Building language models approach achieves good results in one language and it can…

Computation and Language · Computer Science 2022-11-28 Amir Jafari

Tokenization is fundamental to pretrained language models (PLMs). Existing tokenization methods for Chinese PLMs typically treat each character as an indivisible token. However, they ignore the unique feature of the Chinese writing system…

Computation and Language · Computer Science 2023-02-16 Chenglei Si , Zhengyan Zhang , Yingfa Chen , Fanchao Qi , Xiaozhi Wang , Zhiyuan Liu , Yasheng Wang , Qun Liu , Maosong Sun

Learning language of protein sequences, which captures non-local interactions between amino acids close in the spatial structure, is a long-standing bioinformatics challenge, which requires at least context-free grammars. However, complex…

Formal Languages and Automata Theory · Computer Science 2019-03-20 Witold Dyrka , François Coste , Juliette Talibart

Tokenizing raw texts into word units is an essential pre-processing step for critical tasks in the NLP pipeline such as tagging, parsing, named entity recognition, and more. For most languages, this tokenization step straightforward.…

Computation and Language · Computer Science 2022-03-22 Idan Brusilovsky , Reut Tsarfaty

Natural language is composed of words, but modern large language models (LLMs) process sub-words as input. A natural question raised by this discrepancy is whether LLMs encode words internally, and if so how. We present evidence that LLMs…

Computation and Language · Computer Science 2025-03-04 Guy Kaplan , Matanel Oren , Yuval Reif , Roy Schwartz

Finding an optimal word representation algorithm is particularly important in terms of domain specific data, as the same word can have different meanings and hence, different representations depending on the domain and context. While…

Computation and Language · Computer Science 2025-10-09 Nouman Ahmed , Ronin Wu , Victor Botev