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Early detection of Alzheimer's disease (AD) requires models capable of integrating macro-scale neuroanatomical alterations with micro-scale genetic susceptibility, yet existing multimodal approaches struggle to align these heterogeneous…

The automatic early diagnosis of prodromal stages of Alzheimer's disease is of great relevance for patient treatment to improve quality of life. We address this problem as a multi-modal classification task. Multi-modal data provides richer…

We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…

Methodology · Statistics 2020-05-26 Yin Song , Shufei Ge , Jiguo Cao , Liangliang Wang , Farouk S. Nathoo

Synthesizing amyloid PET scans from the more widely available and accessible structural MRI modality offers a promising, cost-effective approach for large-scale Alzheimer's Disease (AD) screening. This is motivated by evidence that, while…

Image and Video Processing · Electrical Eng. & Systems 2025-11-12 Alec Sargood , Lemuel Puglisi , James H. Cole , Neil P. Oxtoby , Daniele Ravì , Daniel C. Alexander

Fast and accurate MRI image reconstruction from undersampled data is crucial in clinical practice. Deep learning based reconstruction methods have shown promising advances in recent years. However, recovering fine details from undersampled…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Eric Z. Chen , Puyang Wang , Xiao Chen , Terrence Chen , Shanhui Sun

We propose to apply a 2D CNN architecture to 3D MRI image Alzheimer's disease classification. Training a 3D convolutional neural network (CNN) is time-consuming and computationally expensive. We make use of approximate rank pooling to…

Computer Vision and Pattern Recognition · Computer Science 2021-01-14 Xin Xing , Gongbo Liang , Hunter Blanton , Muhammad Usman Rafique , Chris Wang , Ai-Ling Lin , Nathan Jacobs

Image generation can provide physicians with an imaging diagnosis basis in the prediction of Alzheimer's Disease (AD). Recent research has shown that long-term AD predictions by image generation often face difficulties maintaining…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Xin Hong , Xinze Sun , Yinhao Li , Yen-Wei Chen

Alzheimer's disease (AD) is an irreversible, progressive neuro degenerative disorder that slowly destroys memory and thinking skills and eventually, the ability to carry out the simplest tasks. In this paper, a deep neural network based…

Image and Video Processing · Electrical Eng. & Systems 2021-05-17 Manu Subramoniam , Aparna T. R. , Anurenjan P. R. , Sreeni K. G

Detection of Alzheimer's Disease (AD) from neuroimaging data such as MRI through machine learning have been a subject of intense research in recent years. Recent success of deep learning in computer vision have progressed such research…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Marcia Hon , Naimul Khan

Alzheimer's Disease (AD) is the most common type of dementia. In all leading countries, it is one of the primary reasons of death in senior citizens. Currently, it is diagnosed by calculating the MSME score and by the manual study of MRI…

Machine Learning · Computer Science 2019-12-11 Rishu Garg , Rekh Ram Janghel , Yogesh Rathore

Predicting conversion from Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) is critical for early intervention. Current deep learning paradigms predominantly rely on cross-sectional structural MRI, neglecting prognostic value in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Alireza Moayedikia , Sara Fin , Alicia Troncoso Lora , Uffe Kock Wiil

Objective: This study aims to support early diagnosis of Alzheimer's disease and detection of amyloid accumulation by leveraging the microstructural information available in multi-shell diffusion MRI (dMRI) data, using a vision…

Computer Vision and Pattern Recognition · Computer Science 2026-01-08 Quentin Dessain , Nicolas Delinte , Bernard Hanseeuw , Laurence Dricot , Benoît Macq

Score-based generative models have demonstrated highly promising results for medical image reconstruction tasks in magnetic resonance imaging or computed tomography. However, their application to Positron Emission Tomography (PET) is still…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Imraj RD Singh , Alexander Denker , Riccardo Barbano , Željko Kereta , Bangti Jin , Kris Thielemans , Peter Maass , Simon Arridge

Alzheimer's disease (AD) is a neurodegenerative disorder that is beginning with amyloidosis, followed by neuronal loss and deterioration in structure, function, and cognition. The accumulation of amyloid-beta in the brain, measured through…

Medical image segmentation can provide detailed information for clinical analysis which can be useful for scenarios where the detailed location of a finding is important. Knowing the location of disease can play a vital role in treatment…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Abhishek Srivastava , Sukalpa Chanda , Debesh Jha , Michael A. Riegler , Pål Halvorsen , Dag Johansen , Umapada Pal

Multimodal medical image fusion is a crucial task that combines complementary information from different imaging modalities into a unified representation, thereby enhancing diagnostic accuracy and treatment planning. While deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Meng Zhou , Yuxuan Zhang , Xiaolan Xu , Jiayi Wang , Farzad Khalvati

With the increasing amounts of high-dimensional heterogeneous data to be processed, multi-modality feature selection has become an important research direction in medical image analysis. Traditional methods usually depict the data structure…

Computer Vision and Pattern Recognition · Computer Science 2022-04-11 Yuang Shi , Chen Zu , Mei Hong , Luping Zhou , Lei Wang , Xi Wu , Jiliu Zhou , Daoqiang Zhang , Yan Wang

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that progressively impairs memory, decision-making, and overall cognitive function. As AD is irreversible, early prediction is critical for timely intervention and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Mahdieh Behjat Khatooni , Mohsen Soryani

Alzheimer's disease (AD) is a neuro-degenerative disease that can cause dementia and result severe reduction in brain function inhibiting simple tasks especially if no preventative care is taken. Over 1 in 9 Americans suffer from AD induced…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Paul K. Mandal , Rakesh Mahto

We propose a model for diagnosing Autism spectrum disorder (ASD) using multimodal magnetic resonance imaging (MRI) data. Our approach integrates brain connectivity data from diffusion tensor imaging (DTI) and functional MRI (fMRI),…

Neurons and Cognition · Quantitative Biology 2024-10-10 Lu Wei , Yi Huang , Guosheng Yin , Fode Zhang , Manxue Zhang , Bin Liu
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