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Synthesized medical images have several important applications, e.g., as an intermedium in cross-modality image registration and as supplementary training samples to boost the generalization capability of a classifier. Especially,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Zizhao Zhang , Lin Yang , Yefeng Zheng

Spatial control methods using additional modules on pretrained diffusion models have gained attention for enabling conditional generation in natural images. These methods guide the generation process with new conditions while leveraging the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Suhyun Ahn , Wonjung Park , Jihoon Cho , Seunghyuck Park , Jinah Park

In this paper, we aim to synthesize cell microscopy images under different molecular interventions, motivated by practical applications to drug development. Building on the recent success of graph neural networks for learning molecular…

Biomolecules · Quantitative Biology 2020-06-16 Karren Yang , Samuel Goldman , Wengong Jin , Alex Lu , Regina Barzilay , Tommi Jaakkola , Caroline Uhler

Computational tomography (CT) provides high-resolution medical imaging, but it can expose patients to high radiation. X-ray scanners have low radiation exposure, but their resolutions are low. This paper proposes a new conditional diffusion…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Yun Su Jeong , Hye Bin Yoo , Il Yong Chun

Recent score-based diffusion models (SBDMs) show promising results in unpaired image-to-image translation (I2I). However, existing methods, either energy-based or statistically-based, provide no explicit form of the interfered intermediate…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Shikun Sun , Longhui Wei , Junliang Xing , Jia Jia , Qi Tian

Advances in deep-learning-based pipelines have led to breakthroughs in a variety of microscopy image diagnostics. However, a sufficiently big training data set is usually difficult to obtain due to high annotation costs. In the case of…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Lukas Uzolas , Javier Rico , Pierrick Coupé , Juan C. SanMiguel , György Cserey

In recent years, computational pathology has seen tremendous progress driven by deep learning methods in segmentation and classification tasks aiding prognostic and diagnostic settings. Nuclei segmentation, for instance, is an important…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Aman Shrivastava , P. Thomas Fletcher

Conditional diffusion models have exhibited superior performance in high-fidelity text-guided visual generation and editing. Nevertheless, prevailing text-guided visual diffusion models primarily focus on incorporating text-visual…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Ling Yang , Zhilong Zhang , Zhaochen Yu , Jingwei Liu , Minkai Xu , Stefano Ermon , Bin Cui

This work addresses the Brain Magnetic Resonance Image Synthesis for Tumor Segmentation (BraSyn) challenge, which was hosted as part of the Brain Tumor Segmentation (BraTS) challenge in 2023. In this challenge, researchers are invited to…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Ivo M. Baltruschat , Parvaneh Janbakhshi , Matthias Lenga

Accurate medical image segmentation commonly requires effective learning of the complementary information from multimodal data. However, in clinical practice, we often encounter the problem of missing imaging modalities. We tackle this…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Cheng Chen , Qi Dou , Yueming Jin , Hao Chen , Jing Qin , Pheng-Ann Heng

Accurate brain tumor segmentation is crucial for neuro-oncology diagnosis and treatment planning. Deep learning methods have made significant progress, but automatic segmentation still faces challenges, including tumor morphological…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Mingda Zhang

Recent advances in generative modeling have positioned diffusion models as state-of-the-art tools for sampling from complex data distributions. While these models have shown remarkable success across single-modality domains such as images…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Nimrod Berman , Omkar Joglekar , Eitan Kosman , Dotan Di Castro , Omri Azencot

Recent medical imaging studies have given rise to distinct but inter-related datasets corresponding to multiple experimental tasks or longitudinal visits. Standard scalar-on-image regression models that fit each dataset separately are not…

Methodology · Statistics 2022-01-21 Xin Ma , Suprateek Kundu

Despite the significant success achieved by deep learning methods in medical image segmentation, researchers still struggle in the computer-aided diagnosis of abdominal lymph nodes due to the complex abdominal environment, small and…

Image and Video Processing · Electrical Eng. & Systems 2026-02-13 Yongrui Yu , Hanyu Chen , Zitian Zhang , Qiong Xiao , Wenhui Lei , Linrui Dai , Yu Fu , Hui Tan , Guan Wang , Peng Gao , Xiaofan Zhang

Image super-resolution is a fundamentally ill-posed problem because multiple valid high-resolution images exist for one low-resolution image. Super-resolution methods based on diffusion probabilistic models can deal with the ill-posed…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Yutao Yuan , Chun Yuan

Image analysis using more than one modality (i.e. multi-modal) has been increasingly applied in the field of biomedical imaging. One of the challenges in performing the multimodal analysis is that there exist multiple schemes for fusing the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-19 Zhe Guo , Xiang Li , Heng Huang , Ning Guo , Quanzheng Li

Objective: While recent advances in text-conditioned generative models have enabled the synthesis of realistic medical images, progress has been largely confined to 2D modalities such as chest X-rays. Extending text-to-image generation to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Daniele Molino , Camillo Maria Caruso , Filippo Ruffini , Paolo Soda , Valerio Guarrasi

Latent Diffusion Models (LDMs) enable high-quality image synthesis while avoiding excessive compute demands by training a diffusion model in a compressed lower-dimensional latent space. Here, we apply the LDM paradigm to high-resolution…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Andreas Blattmann , Robin Rombach , Huan Ling , Tim Dockhorn , Seung Wook Kim , Sanja Fidler , Karsten Kreis

In this paper, we introduce a novel 3D-aware image generation method that leverages 2D diffusion models. We formulate the 3D-aware image generation task as multiview 2D image set generation, and further to a sequential…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Jianfeng Xiang , Jiaolong Yang , Binbin Huang , Xin Tong

Masked Image Modeling (MIM) has garnered significant attention in self-supervised learning, thanks to its impressive capacity to learn scalable visual representations tailored for downstream tasks. However, images inherently contain…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Wenzhao Xiang , Chang Liu , Hongyang Yu , Xilin Chen