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A free boundary value problem related to the genesis of multispecies granular biofilms is presented. The granular biofilm is modelled as a spherical free boundary domain with radial symmetry. The proposed model is conceived in the framework…

Analysis of PDEs · Mathematics 2023-01-31 F. Russo , M. R. Mattei , A. Tenore , B. D'Acunto , V. Luongo , L. Frunzo

This work presents the existence and uniqueness of solution to a free boundary value problem related to biofilm growth. The problem consists of a system of nonlinear hyperbolic partial differential equations governing the microbial species…

Analysis of PDEs · Mathematics 2025-03-26 Dieudonné Zirhumanana Balike , Luigi Frunzo , Maria Rosaria Mattei , Fabiana Russo

The dynamics of biofilm lifecycle are deeply influenced by the surrounding environment and the interactions between sessile and planktonic phenotypes. Bacterial biofilms typically develop in three distinct stages: attachment of cells to a…

Analysis of PDEs · Mathematics 2021-07-07 B. D'Acunto , L. Frunzo , V. Luongo , M. R. Mattei , A. Tenore

In this paper, we consider a model with tumor microenvironment involving nutrient density, extracellular matrix and matrix-degrading enzymes, which satisfy a coupled system of PDEs with a free boundary. For this coupled parabolic-hyperbolic…

Analysis of PDEs · Mathematics 2018-08-24 Rui Li , Bei Hu

In this paper a reduced one-dimensional moving boundary model is studied that describes the evolution of a biofilm driven by the presence of a reaction limiting substrate. Global well-posedness is established for the resulting parabolic…

Analysis of PDEs · Mathematics 2025-05-30 Patrick Guidotti , Christoph Walker

Microfiltration technology is a widely used engineering strategy for fresh water production and water treatment. The major concern in many applications is the formation of a biological fouling layer leading to increased hydraulic resistance…

Biological Physics · Physics 2021-04-12 V. Luongo , M. R. Mattei , L. Frunzo , B. D'Acunto , K. Gupta , S. Chellam , N. G. Cogan

The work presents the analysis of the free boundary value problem related to the invasion model of new species in biofilm reactors. In the framework of continuum approach to mathematical modelling of biofilm growth, the problem consists of…

Biological Physics · Physics 2021-04-09 Berardino D'Acunto , Luigi Frunzo , Vincenzo Luongo , Maria Rosaria Mattei

A mathematical model for emerging contaminants sorption in multispecies biofilms, based on a continuum approach and mass conservation principles is presented. Diffusion of contaminants within the biofilm is described using a…

Cell Behavior · Quantitative Biology 2017-06-15 Luigi Frunzo

We investigate a mathematical model for a bacterial population in a continuously stirred tank reactor with wall attachment. The model couples a free-boundary value problem for substrate diffusion in the one-dimensional biofilm with a system…

Analysis of PDEs · Mathematics 2026-03-12 Katerina Nik , Christoph Walker

The evolution problem for a membrane based model of an electrostatically actuated microelectromechanical system (MEMS) is studied. The model describes the dynamics of the membrane displacement and the electric potential. The latter is a…

Analysis of PDEs · Mathematics 2012-11-27 Joachim Escher , Philippe Laurencot , Christoph Walker

In this volume a theory for models of transport in the presence of a free boundary is developed. Macroscopic laws of transport are described by PDEs. When the system is open, there are several mechanisms to couple the system with the…

Probability · Mathematics 2016-07-28 Gioia Carinci , Anna De Masi , Cristian Giardinà , Errico Presutti

Free boundaries of biofilms advancing on surfaces evolve according to conservation laws coupled with systems of partial differential equations for velocities, pressures and chemicals affecting cell behavior. Thin film approximations lead to…

Analysis of PDEs · Mathematics 2024-03-18 Ana Carpio , Gema Duro

Two phase solid-fluid mixture models are ubiquitous in biological applications. For instance, models for growth of tissues and biofilms combine time dependent and quasi-stationary boundary value problems set in domains whose boundary moves…

Analysis of PDEs · Mathematics 2024-01-17 Ana Carpio , Gema Duro

Well-posedness of a free boundary problem for electrostatic microelectromechanical systems (MEMS) is investigated when nonlinear bending effects are taken into account. The model describes the evolution of the deflection of an electrically…

Analysis of PDEs · Mathematics 2014-09-26 Philippe Laurencot , Christoph Walker

The dynamical and stationary behaviors of a fourth-order evolution equation with clamped boundary conditions and a singular nonlocal reaction term, which is coupled to an elliptic free boundary problem on a non-smooth domain, are…

Analysis of PDEs · Mathematics 2013-08-29 Philippe Laurencot , Christoph Walker

A multiscale mathematical model describing the genesis and ecology of algal-bacterial photogranules and the metals biosorption on their solid matrix within a sequencing batch reactor (SBR) is presented. The granular biofilm is modelled as a…

Cell Behavior · Quantitative Biology 2023-01-31 F. Russo , A. Tenore , M. R. Mattei , L. Frunzo

Consider the thin-film equation $h_t + \left(h h_{yyy}\right)_y = 0$ with a zero contact angle at the free boundary, that is, at the triple junction where liquid, gas, and solid meet. Previous results on stability and well-posedness of this…

Analysis of PDEs · Mathematics 2020-08-25 Manuel V. Gnann , Slim Ibrahim , Nader Masmoudi

A multiscale mathematical model is presented to describe the de novo granulation and the evolution of multispecies granular biofilms within a continuous reactor. The granule is modelled as a spherical free boundary domain with radial…

Populations and Evolution · Quantitative Biology 2022-02-02 A. Tenore , F. Russo , M. R. Mattei , B. D'Acunto , G. Collins , L. Frunzo

In this paper we consider a system of two coupled nonlinear diffusion--reaction partial differential equations (PDEs) which model the growth of biofilm and consumption of the nutrient. At the scale of interest the biofilm density is subject…

Numerical Analysis · Mathematics 2020-01-03 Azhar Alhammali , Malgorzata Peszynska

The dynamics of a free boundary problem for electrostatically actuated microelectromechanical systems (MEMS) is investigated. The model couples the electric potential to the deformation of the membrane, the deflection of the membrane being…

Analysis of PDEs · Mathematics 2013-02-26 Joachim Escher , Philippe Laurencot , Christoph Walker
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