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Continuously measured arterial blood velocity can provide insight into physiological parameters and potential disease states. The efficient and effective description of the temporal profiles of arterial velocity is crucial for both clinical…

Quantitative Methods · Quantitative Biology 2024-02-16 Justen R Geddes , Amanda Randles

In this work, we have performed numerical simulations of the flapping motion of a rectangular wing in a three-dimensional flow field using the discrete vortex method (DVM). The DVM method is computationally more convenient because it does…

Fluid Dynamics · Physics 2023-09-28 Rahul Kumar , Srikant S. Padhee , Devranjan Samanta

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

Statistical properties of circulation encode relevant information about the multi-scale structure of turbulent cascades. Recent massive computational efforts have posed challenging theoretical issues, as the dependence of circulation…

Fluid Dynamics · Physics 2020-11-04 G. B. Apolinário , L. Moriconi , R. M. Pereira , V. J. Valadão

The study of thrombosis is crucial to understand and develop new therapies for diseases like deep vein thrombosis, diabetes related strokes, pulmonary embolism etc. The last two decades have seen an exponential growth in studies related to…

Medical Physics · Physics 2019-11-28 Sumith Yesudasan , Rodney D. Averett

We introduce a multiphysics and geometric multiscale computational model, suitable to describe the hemodynamics of the whole human heart, driven by a four-chamber electromechanical model. We first present a study on the calibration of the…

Numerical Analysis · Mathematics 2024-03-06 Alberto Zingaro , Michele Bucelli , Roberto Piersanti , Francesco Regazzoni , Luca Dede' , Alfio Quarteroni

Segmentation of the left ventricle in cardiac magnetic resonance imaging MRI scans enables cardiologists to calculate the volume of the left ventricle and subsequently its ejection fraction. The ejection fraction is a measurement that…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Garvit Chhabra , J. H. Gagan , J. R. Harish Kumar

Cardiac blood flow patterns contain rich information about disease severity and clinical interventions, yet current imaging and computational methods fail to capture underlying relational structures of coherent flow features. We propose a…

Computational fluid dynamics is intensively used to deepen the understanding of aneurysm growth and rupture in the attempt to support physicians during therapy planning. Numerous studies have assumed fully-rigid vessel walls in their…

Fluid Dynamics · Physics 2023-08-17 Aurèle Goetz , Pablo Jeken Rico , Yves Chau , Jacques Sédat , Aurélien Larcher , Elie Hachem

Mathematical models and numerical simulations offer a non-invasive way to explore cardiovascular phenomena, providing access to quantities that cannot be measured directly. In this study, we start with a one-dimensional multiscale blood…

Machine Learning · Computer Science 2026-04-09 Giulia Bertaglia , Raffaella Fiamma Cabini

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

The multi-cellular hydrodynamic interactions play a critical role in the phenomenology of blood flow in the microcirculation. A fast algorithm has been developed to simulate large numbers of cells modeled as elastic thin membranes. For red…

Fluid Dynamics · Physics 2008-10-14 Amir H. G. Isfahani , Hong Zhao , Jonathan B. Freund

A physics-based data-driven computational framework for the quantitative analysis of vortex kinematics and vortex-induced loads in vortex-dominated problems is presented. Such flows are characterized by the dominant influence of a small…

Fluid Dynamics · Physics 2021-07-28 Karthik Menon , Rajat Mittal

Vortex rings have the ability to transport fluid over long distances. They are usually produced by ejecting a volume of fluid through a circular orifice or nozzle. When the volume and velocity of the ejected fluid are known, the vortex'…

Fluid Dynamics · Physics 2021-07-20 Guillaume de Guyon , Karen Mulleners

Computational hemodynamics models are becoming increasingly useful in the management and prognosis of complex, multiscale pathologies, including those attributed to the development of pulmonary vascular disease. However, diseases like…

Tissues and Organs · Quantitative Biology 2025-06-06 Mitchel J. Colebank , Naomi C. Chesler

The fluid dynamics video presented here outlines recent advances in the simulation of multiphase cellular blood flow through the direct numerical simulations of deformable red blood cells (RBCs) demonstrated through several numerical…

Fluid Dynamics · Physics 2010-10-18 Daniel A. Reasor , Jonathan R. Clausen , Brian M. Yun , Cyrus K. Aidun

Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…

Systematic in vivo validations of computational models of the aortic valve remain scarce, despite successful validation against in vitro data. Utilizing a combination of computed tomography and 4D flow magnetic resonance imaging data, we…

In this paper, we are concerned with the simulation of blood flow in microvascular networks and the surrounding tissue. To reduce the computational complexity of this issue, the network structures are modeled by a one-dimensional graph,…

Numerical Analysis · Mathematics 2023-05-01 Ettore Vidotto , Timo Koch , Tobias Köppl , Rainer Helmig , Barbara Wohlmuth

In this work we propose a mathematical model that describes the orientation of ventricular cardiac fibers. These fibers are commonly computed as the normalized gradient of certain harmonic potentials, so our work consisted in finding the…

Numerical Analysis · Mathematics 2023-05-03 Nicolás A. Barnafi , Axel Osses
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